scholarly journals PROFIL PENDERITA TUMOR KELENJAR LIUR DI RSUP PROF. DR. R.D. KANDOU MANADO PERIODE JULI 2012-JUNI 2015

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Wirawan Iman ◽  
Marselus Merung ◽  
Ainun Aschorijanto

Abstract: Salivary glands tumours are relatively rare to find. There is still no adequate data about the incidence of salivary gland tumours in Indonesia. The main objective of this research was to cognise the profile of salivary glands tumours patients in Prof. Dr. R.D. Kandou Central General Hospital Manado from July 2012 to June 2015. Methods used is descriptive retrospective. The results showed there are 37 patients with salivary gland(s) tumour(s). Male was 59,5% and female was 40,5%. By age groups found that <19 years for 2.7%, 19-30 years for 8,2%, 31-45 years for 21.6%, 46-60 years for 37,8%, >60 years for 29,7%. Based on the histopathological classification, pleomorphic adenoma for 56.8%, Whartin's tumor for 8.1%, myoepithelioma for 2,7%, basal cell adenoma for 2.7%, oncocytoma for 2.7%, cystadenoma for 5.4%, canalicular adenoma for 2.7%, mucoepidermoid carcinoma for 10.8%, adenocarcinoma for 5.4%, and acinic cell carcinoma for 2.7%. Based on the location of the tumours’ appearance, parotid gland for 83.8%, submandibular gland for 13.5%, minor salivary glands for 2.7%. Based by the incidences annually, first year for 21.6%, second year for 32.3%, and the third year for 46.1%.Conclusion: Males are more than females, most commonly found in the age group of 51-60 years, the most commonly benign tumour found is the pleomorphic adenoma, the most commonly found malign tumour is mucoepidermoid carcinoma, the most commonly location of the tumours’ appearance is the parotid gland. The salivary glands tumours continued to increase during the last three years.Suggestion: Still necessary to do further research about salivary glands tumours.Keywords: salivary glands tumours, age, gender, histopathology, location, profileAbstrak : Tumor kelenjar liur adalah tumor yang relatif sedikit dijumpai ditemukan. Belum ditemukan data yang lengkap tentang kejadian tumor kelenjar liur di Indonesia. Tujuan utama dari penelitian ini adalah untuk mengetahui profil penderita tumor kelenjar liur di RSUP Prof. Dr. R.D. Kandou Manado periode Juli 2012-Juni 2015. Metode penelitian yang digunakan adalah deskriptif retrospektif. Hasil penelitian memperlihatkan terdapat 37 penderita tumor kelenjar liur. Laki-laki sebanyak 59,5% dan perempuan 40,5%. Kelompok usia <16 tahun sebanyak 2,7%, 16-30 tahun sebanyak 8,1%, 31-45 tahun sebanyak 21,6%, 46-60 tahun sebanyak 37,8%, >60 tahun sebanyak 29,7%. Berdasarkan klasifikasi histopatologi jenis pleomorphic adenoma sebanyak 56,8%, Whartin’s tumor sebanyak 8,2%, myoepithelioma sebanyak 2,7%, basal cell adenoma sebanyak 2,7%, oncocytoma sebanyak 2,7%, cystadenoma sebanyak 5,4%, canalicular adenoma sebanyak 2,7%, mucoepidermoid carcinoma sebanyak 10,8%, adenocarcinoma sebanyak 5,4%, acinic cell carcinoma sebanyak 2,7%. Berdasarkan lokasi munculnya tumor, kelenjar parotis sebanyak 83,8%, kelenjar submandibula sebanyak 13,5%, kelenjar liur minor sebanyak 2,7%. Berdasarkan jumlah pertahunnya, tahun pertama sebanyak 21,6%, tahun kedua sebanyak 32,3%, dan tahun ketiga sebanyak 46,1%.Kesimpulan : Penderita laki-laki lebih banyak daripada perempuan, paling banyak ditemukan pada kelompok usia 46-60 tahun, tumor jinak yang paling banyak ditemukan adalah pleomorphic adenoma, tumor ganas yang paling banyak ditemukan adalah mucoepidermoid carcinoma, lokasi tersering munculnya tumor adalah kelenjar parotis. Penderita tumor kelenjar liur terus meningkat selama tiga tahun terakhir.Saran : Perlu dilakukan penelitian lebih lanjut tentang tumor kelenjar liurKata Kunci : tumor kelenjar liur, usia, jenis kelamin, histopatologi, lokasi, profil

Author(s):  
Pritosh Sharma ◽  
Abhijit Vasantkumar Makwana ◽  
Rini Bishnoi ◽  
Shifa Vyas ◽  
Vinod Prakash Goyal

<p class="abstract"><strong>Background:</strong> The objective of this study is to evaluate the diagnostic accuracy of FNAC in parotid gland lesions and it’s correlation with HPE, for better management of patient.</p><p class="abstract"><strong>Methods:</strong> A total of 46 FNAC were done of parotid gland lesion in Pathology department of GMCH from 2016 to 2018. Out of 46 patients of parotid gland lesions 44 were surgically resected by ENT Dept GMCH and formalin fixed specimen were sent to Pathology department and slides were prepared. The cytology and HPE stained slides were studied and correlated clinically.  </p><p class="abstract"><strong>Results:</strong> The cytology features of 44 cases are correlated with HPE. In cytology study: pleomorphic adenoma in 31, benign cystic lesion in 07, basal cell adenoma in 01, mucoepidermoid carcinoma in 04 and adenocystic carcinoma in 01. In HPE study: pleomorphic adenoma in 28, benign cystic lesion in 04, basal cell adenoma in 02 and warthin’s tumor in 02, adenocystic carcinoma in 02, mucoepidermoid carcinoma in 03, acinic cell carcinoma in 01, carcinoma of EX pleomorphic adenoma in 01 and cystadeno carcinoma in 02. The sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy are respectively 55.55%, 100%, 100%, 89.74% and 90.90%.</p><p class="abstract"><strong>Conclusions:</strong> FNAC of the parotid gland is safe and reliable technique in the primary diagnosis of salivary gland lesion. Although, sensitivity of this test has some limitation and to differentiate specific malignant lesion. This study has shown that FNAC has low sensitivity, high specificity, diagnostic accuracy, simple and cost effective for the patients of parotid gland lesion.</p>


2015 ◽  
Vol 5 (3) ◽  
pp. 184-187
Author(s):  
Pratik Dipak Shah ◽  
Srijon Mukherji

ABSTRACT Basal cell adenoma (BCA) is a significantly rare benign salivary gland neoplasm that includes isomorphic basaloid cells. Presence of myoepithelial cell is a characteristic of this tumor. Basal cell adenoma accounts for only 1 to 2% of all salivary gland epithelial tumors. The goal of the paper is to report a rare case of tubular type of BCA arising from parotid gland and discuss its management. How to cite this article Shah PD, Mukherji S. Tubular Type of Basal Cell Adenoma of Parotid Gland: A Rare Entity. J Contemp Dent 2015;5(3):184-187.


e-CliniC ◽  
2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Marcella P. J. Merung

Abstract: Salivary glands tumor is relatively rare. In Indonesia, there’s still no complete data about the estimated incidence of salivary glands tumor. Objective:To determine the histopathology of the salivary gland tumor in Manado from July 2010 to July 2013. Methode: This was a descriptive retrospective study. Result: There were 70 patients had salivary gland tumorswith52.9% femaleand47.1% male). By age groups found that ≤16 age group for 1,4%, 17 - 30 for 28.6%, 31 – 40 for18.%), 41 – 50 for21.4%, 51 – 60 for14.3%, 61 – 70 for8.6%, ≥71 for 7.1%. By classification histopathology, Pleiomorphic adenoma for 57.2%, Whartin’s tumor for 11.4%, Oncocytoma, Mucoepidermoid carcinoma, and Adenocarcinoma each for 5.7%, Adenoid cystic carcinoma for4.3%,Cystadenoma for 3.0%, Myoepithelioma, Basal cell adenoma, Canalicular adenoma, Cystadenocarcinoma,and Large cell lymphoma malignant each for 1.4%. By the location, parotis gland for 47.1%, submandibula gland for 27.1%, minor salivary gland for 12.9% and the other location for 12.9%. Conclusion: Female is more than male, the highest incidence is in the group 17-30 years old, the most common benign tumors is pleomorphic adenoma while the most common type of malignant tumors is mucoepidermoid carcinoma and adenocarcinoma. The most frequent tumor’s location is parotid gland. Keywords: Salivary glands tumor, histopathology.   Abstrak: Tumor kelenjar liur merupakan tumor yang jarang ditemukan. Indonesia masih belum ada data lengkap mengenai insiden tumor kelenjar liur.Tujuan: Untuk mengetahui gambaran histopatologi tumor kelenjar liur di Manado periode Juli 2010 – Juli 2013. Metode:Penelitian ini bersifat deskriptif retrospektif. Hasil: Dari 70 penderita tumor kelenjar liurditemukan perempuan 52,9% dan laki-laki 47,1%. Kelompok usia ≤16 tahun sebanyak 1,4%, 17 - 30 tahun sebanyak 28,6%,31 – 40 tahun sebanyak 18,6%, 41 – 50 tahun sebanyak 21,4%, 51 – 60 tahun sebanyak 14,3%, 61 – 70 tahun sebanyak 8,6%, ≥71 tahun sebanyak 7,1%. Berdasarkan klasifikasi histopatologi jenis Pleimorphic adenoma sebanyak 57,2%, Whartin’s tumor sebanyak 11,4%, Oncocytoma,Mucoepidermoid carcinoma, dan Adenocarcinoma masing-masing sebanyak 5,7%,Adenoid cystic carcinoma sebanyak 4,3%, Cystadenoma sebanyak 3,0%, Myoepithelioma,Basal cell adenoma,Canalicular adenoma, Cystadenocarcinoma,dan Large cell lymphoma malignant masing-masing sebanyak 1,4%. Berdasarkan lokasi tumor, kelenjar parotis sebanyak 47,1%, kelenjar submandibula sebanyak 27,1%, kelenjar liur minor sebanyak 12,9% dan lokasi yang tidak jelas sebanyak 12,9%. Kesimpulan:Penderita perempuan lebih banyak dari laki-laki, insiden tertinggi pada kelompok usia17 – 30 tahun, tumor jinak paling banyak ditemukan adalah pleomorphic adenoma sedangkan tipe ganas adalah mucoepidermoid carcinoma dan adenocarcinoma. Lokasi tumor tersering adalah kelenjar parotis. Kata Kunci: Tumor kelenjar liur, histopatologi.


2019 ◽  
Vol 2019 (10) ◽  
Author(s):  
Hideki Shima ◽  
Takayuki Yoshida ◽  
Kunio Hamada ◽  
Akihide Ito ◽  
Toshiki Ito

Abstract The seromucinous glands of the bronchi can give rise to tumors resembling those of the salivary glands. Basal cell adenoma (BCA) has not been reported in salivary gland-type tumors of the lung. Here, we report a case of an 86-year-old Asian man who suffered from pneumonia in the left upper lung field that may be associated with an endobronchial tumor occluding B1 + 2a + b. The bronchoscopic biopsy of the tumor revealed that the basaloid cells, which constituted a major component of the tumor and were positive for p40/p63 immunohistochemistry, exhibited a cord-like structure. The Ki-67 (MKI67) staining was less than 1% positive. These findings suggest that the endobronchial tumor was BCA of the lung, which caused obstructive pneumonia in the patient.


2017 ◽  
Vol 23 (4) ◽  
pp. 184-188
Author(s):  
Ananya Madiyal ◽  
Babu G. Subhas ◽  
Vidya Ajila ◽  
Shruthi Hegde

Abstract Basal cell adenocarcinoma is an unusual basaloid tumour that usually affects the parotid and very rarely involves the submandibular or minor salivary glands. It constitutes 1.6% of all salivary gland tumours and occurs as an asymptomatic freely mobile mass with occasional lymph node metastasis. Differentiation from benign salivary gland tumours like basal cell adenoma is accomplished by determining the depth of tumour invasion and patterns of growth or infiltration. Although it is categorised as a low-grade malignancy, it has a high propensity for recurrence. Surgical excision with a wide margin is the preferred course of treatment with radiotherapy being reserved only for tumours of the minor salivary glands with a diffuse pattern of infiltration. We present here a case of basal cell adenocarcinoma with a rare presentation in the minor salivary glands of the tongue which arose from a previously treated basal cell adenoma in the same site.


2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Yan Zhou ◽  
Ernesto Martinez Duarte ◽  
David J. Eleff ◽  
Laura J. Tafe ◽  
Jason M. Leibowitz ◽  
...  

Background. The presence of two or more tumor entities growing in adjacent locations within the salivary gland is very rare, and pathologic studies on such lesions are limited, particularly those with molecular information. Since the clinical history and imaging studies are usually nonspecific, accurate diagnosis and clinical management largely depend on a thorough histological examination. Methods and Results. We describe a 71-year-old man with an unusual case of hybrid salivary gland tumor composed of mucoepidermoid carcinoma and basal cell adenoma. Molecular analysis revealed differing driver genetic alterations in each component. Conclusions. Hybrid salivary gland tumors are rare, and their pathogenesis is controversial. The combination of mucoepidermoid carcinoma and basal cell adenoma has not been previously described. While malignant transformation of adenoma to carcinoma seems plausible, gene sequencing was more suggestive of their independent derivation. Key to appropriate surgical management is identifying the more aggressive component, ideally at the time of intraoperative consultation.


1996 ◽  
Vol 115 (1) ◽  
pp. 150-151 ◽  
Author(s):  
Ashutosh Kacker ◽  
Volkan Adsay ◽  
Arnold Komisar

The term basal cell adenoma was used by Kleinsasser and Klien 1 in 1967 to describe benign salivary gland tumors comprised of a single type of epithelium. Basal cell adenocarcinoma is a relatively new entity, and there are only a few cases reported in the literature. It has a morphology like that of a basal cell adenoma but has growth characteristics of a malignant neoplasm.


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