CONGENITAL MALFORMATION OF THE CENTRAL NERVOUS SYSTEM : INCIDENCE, MANAGEMENT AND OUTCOME

2021 ◽  
pp. 65-71
Author(s):  
Rakesh Saxena ◽  
Rachana Bhatnagar ◽  
Renu Kushwaha ◽  
Mukul Singh ◽  
Satyavir Sharma S ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Congenital Malformation ◽  
Congenital Malformations ◽  
Medical College ◽  
The Central Nervous System

INTRODUCTION MATERIAL AND METHODS This study has been conducted on the patients suffering from the congenital malformations of the central nervous system attending/admitted in the department of Surgery/ Pediatrics /Neurosurgery, Nehru hospital, B.R.D. Medical College, Gorakhpur for a period of 12 months. CONCLUSION

scholarly journals Embryology of Spinal Dysraphism and its Relationship to Surgical Treatment

2020 ◽  
Vol 47 (6) ◽  
pp. 736-746
Author(s):  
Matthew E. Eagles ◽  
Nalin Gupta
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Surgical Treatment ◽  
Gestational Age ◽  
Congenital Malformations ◽  
Spinal Dysraphism ◽  
Embryological Development ◽  
Correct Treatment ◽  
Pathological Correlation ◽  
The Central Nervous System

ABSTRACT:Spinal dysraphism is an umbrella term that encompasses a number of congenital malformations that affect the central nervous system. The etiology of these conditions can be traced back to a specific defect in embryological development, with the more disabling malformations occurring at an earlier gestational age. A thorough understanding of the relevant neuroembryology is imperative for clinicians to select the correct treatment and prevent complications associated with spinal dysraphism. This paper will review the neuroembryology associated with the various forms of spinal dysraphism and provide a clinical-pathological correlation for these congenital malformations.

Glioblastoma Multiforme with Hypodipsic Hypernatremia in a Seven-Month-Old Golden Retriever

2016 ◽  
Vol 52 (5) ◽  
pp. 319-324 ◽  
Author(s):  
Stephanie Engel ◽  
Karen Marie Hilling ◽  
Travis Kuder Meuten ◽  
Chad Brendan Frank ◽  
Angela J. Marolf
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Glioblastoma Multiforme ◽  
Glial Cell ◽  
Congenital Malformations ◽  
Cell Tumor ◽  
Golden Retriever ◽  
Neoplastic Process ◽  
Underlying Causes ◽  
The Central Nervous System

ABSTRACT Primary hypodipsic hypernatremia is a rarely reported disease in dogs. Reported underlying causes associated with this disease in dogs include congenital malformations, encephalitis, intracranial neoplasia, and pressure atrophy of the hypothalamus secondary to hydrocephalus. The dog in this report had an infiltrative neoplastic disorder, likely causing damage to the hypothalamic osmoreceptors responsible for the thirst generation. The neoplastic process was identified histopathologically as glioblastoma multiforme, an unusual tumor to occur in a dog this young. A tumor of the central nervous system causing physical destruction of the osmoreceptors has rarely been reported in dogs and none of the previously reported cases involved a glial cell tumor.

scholarly journals Serum metallome in pregnant women and the relationship with congenital malformations of the central nervous system: a case-control study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Jacopo Troisi ◽  
Luigi Giugliano ◽  
Laura Sarno ◽  
Annamaria Landolfi ◽  
Sean Richards ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Inductively Coupled Plasma ◽  
Congenital Malformations ◽  
Limit Of Detection ◽  
Maternal Serum ◽  
Congenital Defects ◽  
Inductively Coupled ◽  
Wide Range ◽  
The Central Nervous System

Abstract Background Congenital malformations of the central nervous system (CNS) consist of a wide range of birth defects of multifactorial origin. Methods Concentrations of 44 metals were determined by Inductively Coupled Plasma Mass Spectrometry in serum of 111 mothers in the second trimester of pregnancy who carried a malformed fetus and compared them with serum concentrations of the same metals in 90 mothers with a normally developed fetus at the same week of pregnancy. Data are reported as means ± standard deviations. Results We found a direct relationship between congenital defects of the CNS and maternal serum concentration of aluminum: it was statistically higher in women carrying a fetus with this class of malformation, compared both to mothers carrying a fetus with another class of malformation (6.45 ± 15.15 μg/L Vs 1.44 ± 4.21 μg/L, p < 0.0006) and to Controls (i.e. mothers carrying a normally-developed fetus) (6.45 ± 15.15 μg/L Vs 0.11 ± 0.51 μg/L, p < 0.0006). Moreover, Aluminum abundances were below the limit of detection in the majority of control samples. Conclusion CAluminum may play a role in the onset of central nervous system malformations, although the exact Aluminum species and related specific type of malformation needs further elucidation.

Teratology of the Central Nervous System, by Harold Kalter. Chicago: The University of Chicago Press, 1968, 483 pp., $17.50

PEDIATRICS ◽  
1969 ◽  
Vol 44 (4) ◽  
pp. 626-627
Author(s):  
Floyd H. Gilles
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Congenital Malformations ◽  
University Of Chicago ◽  
Valuable Source ◽  
The Central Nervous System ◽  
Animal Part ◽  
The University ◽  
University Of Chicago Press

Kalter monograph is a compendium of congenital malformations of the central nervous system organized by agent or method (Part 1) or by animal (Part 2). As such, it is a valuable source of teratological information up to the year 1967. While largely a résumé of literature, it includes a reserved presentation of the author contribution to teratology.

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