scholarly journals STUDY OF VAGINAL INFECTIONS AND ITS RELATION TO PRETERM LABOUR, PPROM, PROM AND ITS OUTCOME AT DMCH, LAHERIASARAI, BIHAR

2020 ◽  
pp. 29-31
Author(s):  
Supriya Kumari ◽  
Surya Narayan ◽  
Kumudini Jha

Background: Prematurity is the cause of 85% of neonatal morbidity and mortality. Recently, vaginal infection has been associated with increased risks for prematurity and premature rupture of membranes (PROM). Since preventive measures can prevent preterm labour and neonatal morbidity and mortality taking these facts into consideration the present study was undertaken to study the role of vaginal infection in preterm labour, PPROM, PROM. Methods: A prospective observational study was done in Obstetrics and Gynaecologty Department of DMCH, Laheriasarai, Bihar. The aim was to study the role of vaginal infections in preterm labour, preterm premature rupture of membranes (PPROM) and premature rupture of membranes (PROM). Objectives of the study were to diagnose vaginal infection by taking high vaginal swab, to study the relation of vaginal infection and preterm labour, PPROM, PROM, to evaluate maternal morbidity, mortality and neonatal outcome. The another objective was to select an appropriate antibiotic therapy. The study was done on 80 patients of preterm labour, PPROM and PROM. Vaginal infection was confirmed by high vaginal swab and neonatal outcome was noted. Results: Out of 80, high vaginal swab had growth in 40 patients and 40 were sterile. CONS were the commonest isolated organism grown followed by candida. RDS was the commonest neonatal complication seen in mothers with vaginal infection who delivered prematurely, thus vaginal infection being a common cause of preterm labour, PPROM and PROM, timely detection and treatment is important to avoid prematurity, associated neonatal morbidity and mortality. Conclusions: study provides important data about microbiological correlate of threatened preterm, preterm labour, PROM, PPROM in our pregnant women and most of pathological isolates were sensitive to ampicillin, taxim and gentamicin.

Author(s):  
Srilakshmi Yarlagadda ◽  
Sajana G. ◽  
Prasuna J. L. Narra

Background: Preterm labour is defined as onset of regular uterine contractions associated with cervical changes between 28-37 completed weeks of gestation. Prematurity is the cause of 85% neonatal morbidity and mortality. Preterm labour has multiple etiologies. Vaginal infections have been associated with increased risk for preterm labour. Screening for genitourinary infections antenatally, especially in high risk cases, prompt recognition and treatment decrease the incidence of preterm labour.Methods: Ours was a prospective and retrospective observational study done at Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation from April 2016 to February 2018 in the Department of Obstetrics and Gynaecology. The aim is to study the association of vaginal infections in preterm labour. A total of 116 women in preterm labor were studied. After clinical examination, CBP, CUE, Ultrasound, urine culture and sensitivity were done. Vaginal swab was taken from posterior fornix and sent for culture and sensitivity and gram staining .Culture and sensitivity were done in the Department of Microbiology at our Institute.Results: Out of 116 women in preterm labour, urinary tract infection was seen in 27.58% women. E. Coli was the commonest microorganism isolated in urine (15.51%). Vaginal infections were seen in 33.62% women. Candida was the commonest microorganism isolated in HVS cultures.Conclusions: Screening for genitourinary infections in pregnancy is necessary, especially in high risk cases. Early detection and prompt treatment of genitourinary infections decrease the incidence of preterm labor, thereby decreasing the neonatal morbidity and mortality associated with prematurity.


2020 ◽  
Vol 11 (4) ◽  
pp. 6136-6143
Author(s):  
Amruta Choudhary ◽  
Sudha Rani ◽  
Gunchoo Kundi ◽  
Arpita Jaiswal

Premature rupture of membranes (PROM) affects approximately 10% of pregnant women. PROM, when unattended or mismanaged may lead to severe maternal and neonatal complications. The present study aims to study the subsequent course of pregnancy and evaluate the maternal, and neonatal morbidity and mortality in PROM patients admitted in our hospital. To study the outcome of PROM and assess the maternal and perinatal morbidity and mortality. It was a prospective observational study. All the patients of PROM admitted in hospital and considered based on inclusion and exclusion criteria were included in the study. They were induced with either oxytocin or misoprostol depending on their Bishops score. In the group of patients, where PROM delivery interval >18 hours were found to have more maternal complications like puerperal sepsis, chorioamnionitis, wound gape, paralytic ileus, and more neonatal complications like jaundice, sepsis. In our study, maternal morbidity was directly related to the PROM delivery interval. Thus, women diagnosed with PROM should be hospitalised early or referred early to tertiary hospital and actively managed and followed up till delivery. Timely referral and timely intervention can further improve perinatal outcome.


Author(s):  
Sailaja Surayapalem ◽  
Vijayalakshmi Cooly ◽  
Bhuvaneswari Salicheemala

Background: Premature rupture of membranes is defined as rupture of foetal membranes before the onset of labour. Management of cases of PROM still remains as one of the most difficult and controversial problems in obstetrics. PROM can cause maternal complications like chorioamnionitis, increased operative procedures, puerperal sepsis and neonatal morbidity and mortality. The present study is undertaken to study the labour outcome, maternal morbidity and perinatal morbidity and mortality in term PROM.Methods: 200 Cases of spontaneous rupture of membranes with gestational age >37 weeks with confirmed PROM by a speculum examination were selected. A detailed history was taken, and gestational age confirmed, general, systemic and obstetric examinations were done. Parameters of maternal and foetal well being were recorded. All study groups received prophylactic antibiotics. Single pelvic examination done, and maternal vitals recorded fourth hourly. All the data was analyzed and statistical significance was calculated using Chi-square test.Results: PROM was common in age group of 20-24 years (35%) with mean age of 22.6 years and SD of 2.8 years, and common in primigravida. Majority of women were admitted within six hours of PROM (41.5%) and Mean duration of induction to delivery interval was 12.9 hours. The mean duration between PROM to delivery was 20.2 hours which was statistically significant. Cesarean sections were more among primigravidas. Failure to progress was the common indication. Maternal morbidity was significant (17.5%). No maternal mortality in the study. Perinatal mortality was 1.5%. Birth asphyxia was the commonest cause. Perinatal morbidity was seen in 26%. Escherichia coli was common organism found in cervical swab culture.Conclusions: In present study, majority was primigravidas and the most common age group was 20-24 years belonging to low socioeconomic status. Maternal morbidity and neonatal morbidity was associated with increased duration of PROM to delivery and infection of the female genital tract with pathogens. Hence an appropriate and accurate diagnosis of PROM is essential for favorable outcome in pregnancy.


2004 ◽  
Vol 24 (3) ◽  
pp. 284-284
Author(s):  
S. Hernández Aguado ◽  
T. Cobo ◽  
M. Palacio ◽  
F. Figueras ◽  
M. Sánchez ◽  
...  

Author(s):  
John Mary Betty Agnes ◽  
Sowmyanarayanan Lavanya

Background: Premature rupture of membranes (PROM) has an incidence of about 10% of all pregnancies and is a significant event as it can cause maternal complications, neonatal morbidity and mortality. Some believe that the expectant management of PROM at term does not increase the perinatal and maternal morbidity, and immediate induction of labour leads to an increased caesarean section rate. There are some authors who report a significant increase in the rates of neonatal, maternal infection and foetal distress if delivery occurs over 24 hours after PROM. Thus, a data is required to manage the cases of PROM to effect safe delivery for both mother and baby. The objective of the study was to compare the neonatal and maternal outcomes between immediate and delayed induction with PG E2 gel in term PROM.Methods: A hospital based study in women admitted to Obstetrics and Gynaecology Department at R.S.R.M Hospital with a sample of 400 patients in age group between 19- 35 years with gestational age between 37 and 41 weeks were selected for the study. All the 400 cases who presented with term PROM were admitted in labour room and history was elicited regarding age, menstrual and obstetric history with enquiry regarding the time of rupture of membranes, duration and amount of leaking with general, systemic and detailed obstetric examination.Results: The number of PG E2 gel needed for induction varied between the two groups. Around 45 patients in group 2 needed second dose of gel whereas only 32 patients required the second dose in the late induction group and 72 cases got into active labour. There was no difference in maternal and neonatal infectious morbidity between the two groups. This may be due to the use of prophylactic antibiotics. Neonatal outcome was equally good in both the groups.Conclusions: Delayed induction of labour in PROM after a waiting period of 12 hours stands as a reasonable option as it reduces the number of operative deliveries without compromising the maternal and neonatal outcome.


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