Renal colic secondary to ureteral metastasis: Rare presenting manifestation of prostate cancer

Objective: Ureteral metastasis of prostate cancer is a very rare pathology, that can be confused with an upper urinary tract urothelial carcinoma, with great implications in the surgical management and therapy of the disease. Case: A 56-years old male patient admitted to the emergency room with 2 weeks history of left flank pain without low urinary tract symptoms or hematuria. PSA level was 43,4 ng/ml. The patient underwent prostate needle biopsy and ureteral biopsy using flexible ureteroscopy, after the Lich-Gregoire ureterovesical reimplantation. In this case, renal colic as the first symptom of a ureteral metastasis secondary to prostate cancer is extremely rare which diagnosed in the patient. Conclusion: Neoureterocystostomy is a safe and effective treatment for ureteral obstruction due to prostate cancer metastasis, with low morbidity and significant benefits in terms of quality of life for patients with life expectancy more than 10 years.

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Prostate cancer metastasis to the testis: an unexpected presentation of a solitary recurrence

BMJ Case Reports ◽

10.1136/bcr-2020-237853 ◽

2021 ◽

Vol 14 (3) ◽

pp. e237853

Author(s):

Conor McCann ◽

Anna Doherty ◽

Ciaran Flynn ◽

Colin Mulholland

Keyword(s):

Prostate Cancer ◽

Cancer Metastasis ◽

External Beam Radiotherapy ◽

New Left ◽

Specific Antigen ◽

Metastatic Spread ◽

Histopathological Analysis ◽

Good Recovery ◽

Prostate Cancer Metastasis ◽

History Of

A 74-year-old man with a history of prostate cancer was referred to the urology team with a new left sided testicular lump. He had a background of prostate cancer 4 years previous which had been treated with external beam radiotherapy and androgen deprivation therapy, both of which had been completed. Concurrently, he also had evidence of biochemical recurrence of prostate cancer with a rising prostate-specific antigen (PSA). He underwent a left radical orchidectomy. Following histopathological analysis, this was found to be metastatic spread from his prostate cancer. Subsequent staging showed no evidence of metastatic spread elsewhere. The patient made a good recovery following surgery and his PSA levels returned to undetectable levels. He received no further treatment for metastatic prostate cancer.

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Pancytopenia as an initial manifestation of prostate cancer: a case report

Journal of Medical Case Reports ◽

10.1186/s13256-021-02843-0 ◽

2021 ◽

Vol 15 (1) ◽

Author(s):

Marcos Antonio Custódio Neto da Silva ◽

Vitor Pimentel Rodrigues Manhães ◽

Luadir Gasparotto Júnior ◽

Daniela Miti Lemos Tsukumo ◽

Cristina Alba Lalli

Keyword(s):

Prostate Cancer ◽

Bone Marrow ◽

Cancer Metastasis ◽

Cancer Type ◽

Initial Manifestation ◽

Additional Information ◽

Cancer Management ◽

Urinary Tract Symptoms ◽

Prostate Cancer Metastasis ◽

Tumor Involvement

Abstract Background Prostate adenocarcinoma is the most frequent cancer type among men, followed by skin cancer. Patients with prostate cancer usually present lower urinary tract symptoms due to tumor involvement. Bone marrow invasion is associated with prostate cancer metastasis and is common if blastic lesions in bones are present but is very rare without a large bone involvement and uncommon as initial presentation. Case presentation We present a case of an 86-year-old Caucasian man with bone marrow invasion of prostate cancer without urological or bone-related symptoms and without prostate nodules. His findings were dyspnea, fatigue, and tachycardia. We detail the complete investigation of the case until we found the accurate diagnosis. The patient started treatment, but he had no response and so the oncology team started palliative care. Conclusion Bone marrow invasion as an initial manifestation of prostate cancer is not common, especially if no prostatic lesions are found. This report is important to provide additional information about prostate cancer management.

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