scholarly journals Brain volumetric MRI study in healthy adolescent and young person’s using automated method

2021 ◽  
Vol 8 (9) ◽  
pp. 531-537
Author(s):  
Seda Avnioğlu ◽  
Özkan Özen
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
Morphological Changes ◽  
Young Subject ◽  
Resonance Imaging ◽  
Brain Volumes ◽  
Healthy Adolescent ◽  
Automated Method ◽  
Age Related

Objective: Adolescence is a critical period for the maturation of neurobiological processes that underlie higher cognitive functions and social and emotional behaviour. However, there are limited studies that investigated brain volumes in healthy adolescents and young persons.  The aim of this study was to compare the Grey Matter (GM), White Matter (WM) and some specific brain subcortical volumes such as hippocampus and amygdala between healthy adolescents and young groups by using VolBrain. Material and Methods: Magnetic resonance imaging brain scans were retrospectively obtained from 20 healthy adolescent and young subjects.  The mean ages of the adolescent and young persons were 13±1 and 24±2, respectively. Brain parenchyma (BP), GM, WM and asymmetry features were calculated using VolBrain, and the GM and WM volumes of each subjects were compared with those of the both groups. The current study to examine whether regional gray matter (GM), white matter (WM), cerebrospinal fluid (CSF), some brain subcortical structures volumes differed between healthy adolescent and young groups. Also, of the whole brain, hemispheres, and hippocampus, amigdala of adolescent and young subject volumes were measured with an automated method. Results: We have observed that the young group was found to have a 4 % less in volume of GM, when compared with adolescent groups. Conclusion: Our data indicate that quantitative structural Magnetic Resonance Imaging (MRI) data of the adolescent brain is important in understanding the age-related human morphological changes.

scholarly journals Visual Rating of Age-Related White Matter Changes on Magnetic Resonance Imaging

Stroke ◽  
2003 ◽  
Vol 34 (2) ◽  
pp. 441-445 ◽  
Author(s):  
P. Kapeller ◽  
R. Barber ◽  
R.J. Vermeulen ◽  
H. Adèr ◽  
P. Scheltens ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
Resonance Imaging ◽  
White Matter Changes ◽  
Visual Rating ◽  
Age Related

scholarly journals Long-Term Morphological Changes of Symptomatic Lacunar Infarcts and Surrounding White Matter on Structural Magnetic Resonance Imaging

Stroke ◽  
2018 ◽  
Vol 49 (5) ◽  
pp. 1183-1188 ◽  
Author(s):  
Caroline M.J. Loos ◽  
Stephen D.J. Makin ◽  
Julie Staals ◽  
Martin S. Dennis ◽  
Robert J. van Oostenbrugge ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
Morphological Changes ◽  
Resonance Imaging ◽  
Structural Magnetic Resonance Imaging ◽  
Lacunar Infarcts

scholarly journals Magnetic resonance imaging findings in children with Parry-Romberg syndrome and en coup de sabre

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Harry Knights ◽  
Elizabeth Minas ◽  
Faraan Khan ◽  
Lindsay Shaw ◽  
Muthana Al Obaidi ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
Brain Imaging ◽  
Case Series ◽  
Dystrophic Calcification ◽  
Resonance Imaging ◽  
Cutaneous Manifestations ◽  
Street Hospital ◽  
Parry Romberg Syndrome

Abstract Background The aim of this study was to: (i) describe the abnormalities seen on brain imaging in a group of children with en coup de sabre (EDCS) with/without Parry-Romberg syndrome (PRS); and (ii) identify clinical predictors of brain imaging abnormalities. Methods This was a single centre (Great Ormond Street Hospital, London) retrospective case series of patients with ECDS/PRS seen from 2000 to 2018. We identified patients with cutaneous manifestations consistent with the clinical descriptions of ECDS/PRS. Presenting clinical, laboratory, and radiological brain findings are described. Results are expressed as medians and ranges or frequencies and percentages. Fisher’s exact test was used to identify clinical associations with magnetic resonance imaging (MRI) abnormalities. Results Fourteen patients were studied: 6 males and 8 females; median age 14 years (range 3–20). We observed neuroimaging abnormalities in 2/6 ECDS and 5/8 ECDS/PRS patients. White matter signal abnormality, dystrophic calcification, leptomeningeal enhancement, and sulcal crowding were the typical findings on brain imaging. A total of 50% of patients had no MRI abnormality despite some of these patients having neurological symptoms. The presence of seizures was significantly associated with ipsilateral enhanced white matter signalling on MRI (p < 0.05). Conclusions In summary, we observed several distinct radiographic patterns associated with ECDS/PRS. Seizure disorder was strongly associated with the presence of ipsilateral enhanced white matter signalling. Improved neuroimaging techniques that combine morphological with functional imaging may improve the detection rate of brain involvement in children with ECDS/PRS in the future.

scholarly journals ASPREE-NEURO study protocol: A randomized controlled trial to determine the effect of low-dose aspirin on cerebral microbleeds, white matter hyperintensities, cognition, and stroke in the healthy elderly

2016 ◽  
Vol 12 (1) ◽  
pp. 108-113 ◽  
Author(s):  
Stephanie A Ward ◽  
Parnesh Raniga ◽  
Nicholas J Ferris ◽  
Robyn L Woods ◽  
Elsdon Storey ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Primary Prevention ◽  
Magnetic Resonance ◽  
Controlled Trial ◽  
Brain Magnetic Resonance Imaging ◽  
Cerebral Microbleeds ◽  
Resonance Imaging ◽  
Healthy Elderly ◽  
Cerebral Microbleed

Rationale Cerebral microbleeds seen on brain magnetic resonance imaging are markers of small vessel disease, linked to cognitive dysfunction and increased ischemic and hemorrhagic stroke risk. Observational studies suggest that aspirin use may induce cerebral microbleeds, and associated overt intracranial hemorrhage, but this has not been definitively resolved. Aims ASPREE-NEURO will determine the effect of aspirin on cerebral microbleed development over three years in healthy adults aged 70 years and over, participating in the larger ‘ASPirin in Reducing Events in the Elderly (ASPREE)’ primary prevention study of aspirin. Sample size Five hundred and fifty-nine participants provide 75% power (two-sided p value of 0.05) to determine an average difference of 0.5 cerebral microbleed per person after three years. Methods and design A multi-center, randomized placebo-controlled trial of 100 mg daily aspirin in participants who have brain magnetic resonance imaging at study entry, one and three years after randomization and who undergo cognitive testing at the same time points. Study outcomes The primary outcome is the number of new cerebral microbleeds on magnetic resonance imaging after three years. Secondary outcomes are the number of new cerebral microbleeds after one year, change in volume of white matter hyperintensity, cognitive function, and stroke. Discussion ASPREE-NEURO will resolve whether aspirin affects the presence and number of cerebral microbleeds, their relationship with cognitive performance, and indicate whether consideration of cerebral microbleeds alters the risk-benefit profile of aspirin in primary prevention for older people. Trial registration Australian New Zealand Clinical Trials Registry ACTRN12613001313729.

Magnetic resonance imaging cinecisternography in patients with white matter lesions

1992 ◽  
Vol 2 (4) ◽  
pp. 213-215
Author(s):  
Yasuo Fukuuchi ◽  
Takahiro Amano ◽  
Hayao Shiga ◽  
Makoto Ichijo ◽  
Yoshiaki Itoh ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
White Matter Lesions ◽  
Resonance Imaging
Sign in / Sign up

Export Citation Format

Share Document