scholarly journals Relationship of Glucose Variability and Daily Lifestyle by Continuous Glucose Monitoring (CGM)

2020 ◽  
Vol 3 (3) ◽  
pp. 206-212
Author(s):  
Yamashita H ◽  
Kato Y ◽  
Bando H ◽  
Kanazawa S ◽  
Tanaka M ◽  
...  
Keyword(s):  
Continuous Glucose Monitoring ◽  
Glucose Monitoring ◽  
Glucose Variability ◽  
Future Research ◽  
Low Carbohydrate Diet ◽  
Freestyle Libre ◽  
Low Carbohydrate ◽  
Working Day ◽  
Multiple Daily Insulin Injections ◽  
Relationship Of

Authors and collaborators have continued diabetic practice and research on low carbohydrate diet (LCD), continuous glucose monitoring (CGM), and so on. The case is a 64-year-old male with type 2 diabetes mellitus (T2DM) treated with multiple daily insulin injections (MDI). When his HbA1c was 8.2% before, he changed to take tofu instead of rice and bread. HbA1c decreased to 7.1% and 4kg of weight reduction in 2 months. Tofu is a traditional Japanese food made from soybeans, which is a suitable LCD with Protein:Fat:Carbohydrate (PFC) ratio=40:45:15 in this case. His HbA1c is recently unstable, then glucose variability was investigated by CGM using FreeStyle Libre. The glucose pattern was different due to his lifestyle, including working day, off day, playing golf, respectively. The average glucose was 143-167 mg/dL and the estimated HbA1c was 7.1%, whereas HbA1c in outclinic was 8.1%, respectively. This report will hopefully become reference data for future research.

scholarly journals Normalized glucose variability by Low Carbohydrate Diet (LCD) in CGM study

2019 ◽  
Vol 2 (S1) ◽  
pp. 22-27
Author(s):  
Muneta T ◽  
Kawaguchi E ◽  
Hayashi M ◽  
Bando H ◽  
Ebe K
Keyword(s):  
Ketone Bodies ◽  
Glucose Monitoring ◽  
Glucose Variability ◽  
Carbohydrate Diet ◽  
Glucose Lowering ◽  
Low Carbohydrate Diet ◽  
Freestyle Libre ◽  
Low Carbohydrate ◽  
Glucose Lowering Effect

In diabetic practice, continuous glucose monitoring (CGM) has been more used for glucose variability. Authors have reported and developed the clinical study of Low Carbohydrate Diet (LCD) and Calorie Restriction (CR) through Japan LCD Promotion Association (JLCDPA). A diabetic case is presented with normalizing glucose variability by LCD meal checked by CGM. Case is 51 years female with type 2 diabetes mellitus (T2DM). At first visit, HbA1c was 10.0%, glucose was 288mg/dL, BMI 39.1, GOT 16IU/mL, HDL-C 33mg/dL, Triglyceride 152mg/dL. CR meal was provided on day-1 to day-5 and LCD meal with 12% carbohydrate on day-6 to day-13. Average glucose value from CGM was 292mg/dL, 235mg/dL, 160mg/dL, 140mg/dL, 124mg/dL in day 3,5,7,9,11 respectively. On day-13, total Ketone bodies (T-KB) 540μmol/L (-131), Acetoacetic acid (AcAc) 86μmol/L (-55) and 3-hydroxybutyric acid (3-OHBA) 454μmol/L (-85). Weight reduction was 5kg on day-14 and 11.2kg on day-70 with BMI 34.6. Thus, LCD showed a remarkable glucose-lowering effect in short term. FreeStyle Libre (Abbott, USA) seems to be a useful apparatus for monitoring the detailed fluctuation of blood glucose. These results would become fundamental and reference data and contribute to the LCD research development in the future.

Continuous Glucose Monitoring After Gastric Bypass to Evaluate the Glucose Variability After a Low-Carbohydrate Diet and to Determine Hypoglycemia

2016 ◽  
Vol 26 (9) ◽  
pp. 2111-2118 ◽  
Author(s):  
Joan Bach Nielsen ◽  
Caroline Bruun Abild ◽  
Ane Mathilde Pedersen ◽  
Steen Bønløkke Pedersen ◽  
Bjørn Richelsen
Keyword(s):  
Gastric Bypass ◽  
Continuous Glucose Monitoring ◽  
Glucose Monitoring ◽  
Glucose Variability ◽  
Carbohydrate Diet ◽  
Low Carbohydrate Diet ◽  
Low Carbohydrate

Daily improvement of blood glucose profile by continuous glucose monitoring (CGM)

2019 ◽  
Vol 6 (2) ◽  
pp. 24-26 ◽  
Author(s):  
Hiroshi Bando ◽  
Yoshikane Kato ◽  
Setsuko Kanazawa ◽  
Mayumi Tanaka ◽  
Etsuko Sueki ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Continuous Glucose Monitoring ◽  
Glucose Monitoring ◽  
Insulin Injection ◽  
Glucose Variability ◽  
Diabetic Control ◽  
Future Research ◽  
Glucose Profile ◽  
Insulin Glargin ◽  
Blood Glucose Profile

Background: The problem of glucose variability has been in focus for type 1 diabetes mellitus (T1DM) on insulin treatment. Daily profile of blood glucose was studied on Continuous Glucose Monitoring (CGM) using Free Style Libre. Case presentation and results: Patient is 54 year-old T1DM female, with HbA1c 7.8%. The blood glucose variability was measured by Free Style Libre. Insulin therapy included multiple daily insulin injection (MDI) of Insulin Glargin and Aspart. The result revealed unstable blood glucose profile in day 1 and 2. After that, the level and fluctuation of blood glucose gradually decreased from day 3 to 14. Average blood glucose in a day was 174mg/dL, 159mg/dL, 138mg/dL, 125mg/dL and 110mg/dL, in day 2, 4, 7, 9, 11, respectively. There was a discrepancy of HbA1c between 7.8% by laboratory measurement and 6.3% presumed value by Free Style Libre. Discussion and Conclusion: Free Style Libre showed satisfactory results as CGM. There was lower HbA1c value by presumed calculation, which would be possibly due to every 15minutes measurement and difficulty in checking abrupt glucose surges. CGM application would probably bring diabetic subjects behavioral change of life style, leading to better diabetic control. These results would become reference data in CGM study for future research.

scholarly journals Useful Measurement of Glucose Variability by Flash Glucose Monitoring (FGM) with the Efficacy of Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitor

2020 ◽  
Vol 2 (S1) ◽  
pp. 1-8 ◽  
Author(s):  
Ebe K ◽  
Bando H ◽  
Muneta T ◽  
Bando M ◽  
Yonei Y
Keyword(s):  
Blood Glucose ◽  
Sglt2 Inhibitor ◽  
Glucose Monitoring ◽  
Glucose Variability ◽  
Postprandial Blood Glucose ◽  
Diabetic Patients ◽  
Flash Glucose Monitoring ◽  
Low Carbohydrate Diet ◽  
Sodium Glucose Cotransporter ◽  
Freestyle Libre

Diabetes has been a crucial medical and social problem worldwide. For adequate nutritional therapy, there have been discussions concerning Calorie Restriction (CR) and Low Carbohydrate Diet (LCD). We have investigated glucose variability of diabetic patients applying CR, LCD, continuous glucose monitoring (CGM) and applied FreeStyle Libre which is flash glucose monitoring (FGM). The patient is a 40-year-old female with type 2 diabetes mellitus (T2DM), who showed BMI 20.7, postprandial blood glucose 257 mg/dL. HbA1c 12.1%, Glycoalbumin 31.6% (11.6-16.4), serum C-peptide 2.0 ng/ml and unremarkable data of liver function, renal, lipids. She was provided the intervention of three stages, which are i) CR with 60% carbohydrate in Day 1-2, ii) LCD meal with 12% carbohydrate in Day 3-5; iii) LCD + Sodium-glucose cotransporter 2 (SGLT2) inhibitor (Ipragliflozin L-Proline 50mg) in Day 6-12. The glucose profile was measured by FreeStyle Libre Pro (Abbott) for 14 days. The daily profile of blood glucose was abruptly decreased on Day 6. Time percentage of satisfactory blood glucose 70-180 mg/dL (/24h) was 0%, 0%, 2%, 14%, 0%, 54%, 100% in Day 1-7, respectively. These results suppose the acute clinical efficacy of SGLT2 inhibitor, and this report would become a reference for future diabetic practice and research.

Daily improvement of glucose variability by Continuous Glucose Monitoring (CGM)

2020 ◽  
Vol 2 (1) ◽  
pp. 18-22
Author(s):  
Hiroshi Bando ◽  
Yoshikane Kato ◽  
Setsuko Kanazawa ◽  
Mayumi Tanaka ◽  
Etsuko Sueki ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Continuous Glucose Monitoring ◽  
Glucose Monitoring ◽  
Insulin Injection ◽  
Glucose Variability ◽  
Diabetic Control ◽  
Freestyle Libre ◽  
Daily Insulin Injection ◽  
Average Glucose

Continuous Glucose Monitoring (CGM) has been recently applied in the clinical diabetic practice. Authors have continued research of glucose variability. In this study, 51 year-old female patient with Type 1 diabetes mellitus (T1DM) was investigated. She has given multiple daily insulin injection (MDI) for long and her recent daily glucose profile was unstable. After applied with FreeStyle Libre, her blood variability was improved with the average glucose from 222 mg/dL to 135 mg/dL, which was partly from her motivation for better diabetic control. Thus, CGM may become a trigger to give beneficial influence for regular lifestyle of the patients.

Effect of Continuous Glucose Monitoring on Glycemic Control in Adults Using Multiple Daily Insulin Injections

2017 ◽  
Vol 41 (5) ◽  
pp. S55-S56
Author(s):  
David Price ◽  
Tonya Riddlesworth ◽  
Roy W. Beck ◽  
Harold A. Wolpert ◽  
Richard M. Bergenstal ◽  
...  
Keyword(s):  
Glycemic Control ◽  
Continuous Glucose Monitoring ◽  
Glucose Monitoring ◽  
Daily Insulin ◽  
Multiple Daily Insulin Injections
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