A COMPARATIVE STUDY OF LIPID PROFILE AND LEPTIN RESISTANCE IN CHILDREN WITH METABOLIC SYNDROME DEPENDING ON HYPERTENSION IN KYIV

2021 ◽  
Vol 74 (10) ◽  
pp. 2630-2633
Author(s):  
Maiia H. Aliusef ◽  
Alina V. Churylina ◽  
Ganna V. Gnyloskurenko ◽  
Inga O. Mitiuriaeva ◽  
Vitaliy G. Maidannyk
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
High Density Lipoprotein ◽  
Lipid Profile ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Leptin Resistance ◽  
Normal Blood Pressure

The aim: To compare lipid metabolism and leptin levels among the children with and without hypertension to identify associated risk factors for the course of metabolic syndrome in children. Materials and methods: This observational, cross-sectional study recruited children from the Rheumocardiology Department of Children’s Clinical Hospital No 6 in Kyiv, with metabolic syndrome, identification of waist-to-height ratio, leptin level, homeostasis model assessment of insulin resistance and lipid profile. The main group included 41 children with metabolic syndrome and hypertension and the control group included 40 children with metabolic syndrome without hypertension. Statistical data analysis was performed using the MedStat 2.6.2. package. Results: A total of 81 children aged 10 to 17 with metabolic syndrome were examined. The group of children with hypertension had significantly lower high-density lipoprotein cholesterol (0.85±0.04) than children without hypertension (0.94±0.03), with p < 0.05. Leptin resistance was detected in 65.2% of children with hypertension and 35.3% of children with normal blood pressure (p < 0.01). Conclusions: Children with metabolic syndrome and hypertension had a significantly higher body mass index and waist circumference as opposed to children with normal blood pressure. In the lipid profile high-density lipoprotein cholesterol was significantly lower in hypertensive children. There was no reliable difference in other lipid profile indicators between the two groups, but there was an upward trend of them in group with hypertension. Leptin resistance is also significantly higher in hypertensive children.

The association between plant-based diet indices and metabolic syndrome in Iranian older adults

2021 ◽  
pp. 026010602199267
Author(s):  
Mohammad Reza Amini* ◽  
Hossein Shahinfar ◽  
Farhang Djafari ◽  
Fatemeh Sheikhhossein ◽  
Sina Naghshi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Older Adults ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
High Density Lipoprotein ◽  
Diastolic Blood Pressure ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol

Background: We investigated the association between plant-based diets indices – an overall plant-based diet index; a healthful plant-based diet index; and an unhealthful plant-based diet index – and metabolic syndrome among Iranian older adults. Aim: We aimed to examine the relationship between plant-based diet indices and metabolic syndrome. Methods: This cross-sectional study included 178 older adults (51 men and 127 women), with a mean age of 67.04 (60–83) who were referred to health centers in Tehran, Iran. Blood and urine samples were collected to measure serum total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and triglycerides. We created an overall plant-based diet index, healthful plant-based diet index, and unhealthful plant-based diet index from semi-quantitative food-frequency questionnaire data. Anthropometric measures were done. Results: Our crude model results showed that triglycerides, systolic and diastolic blood pressure, fasting blood sugar, high-density lipoprotein cholesterol, and waist circumference did not significantly differ between tertiles of plant-based diet index and healthful plant-based diet index; also triglycerides, systolic and diastolic blood pressure, fasting blood sugar, and waist circumference did not significantly differ between tertiles of unhealthful plant-based diet index, but high-density lipoprotein cholesterol significantly differed between tertiles of unhealthful plant-based diet index. After adjusting for confounders the results remained non-significant for plant-based diet index but high-density lipoprotein cholesterol was significant for healthful and unhealthful plant-based diet indices. There was also no significant association between plant-based diet index (OR: 1.11; 95% CI: 0.53–2.33), healthful plant-based diet index (OR: 0.81; 95% CI: 0.39–1.68), and unhealthful plant-based diet index (OR: 0.81; 95% CI: 0.38–1.72) with metabolic syndrome, even after adjustment for confounders. Conclusions: Our findings showed that plant-based diets are not significantly associated with risk of metabolic syndrome in older adults. To confirm the veracity of these findings, more studies should be conducted.

scholarly journals High-density lipoprotein-cholesterol functionality and metabolic syndrome

Medicine ◽  
2018 ◽  
Vol 97 (24) ◽  
pp. e11094
Author(s):  
Leonardo Roever ◽  
Elmiro Santos Resende ◽  
Angélica Lemos Debs Diniz ◽  
Nilson Penha-Silva ◽  
João Lucas O’Connell ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol

Association of Physical Activity and Cardiometabolic Risk in Children 3–12 Years

2020 ◽  
Vol 17 (8) ◽  
pp. 800-806
Author(s):  
Leigh M. Vanderloo ◽  
Jonathan L. Maguire ◽  
David W. H. Dai ◽  
Patricia C. Parkin ◽  
Cornelia M. Borkhoff ◽  
...  
Keyword(s):  
Physical Activity ◽  
Blood Pressure ◽  
High Density Lipoprotein ◽  
Systolic Blood Pressure ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Height Ratio ◽  
Waist To Height Ratio

Background: This study aimed to examine the association between physical activity (PA) and a total cardio metabolic risk (CMR) score in children aged 3–12 years. Secondary objectives were to examine the association between PA and individual CMR factors. Methods: A longitudinal study with repeated measures was conducted with participants from a large primary care practice-based research network in Toronto, Canada. Mixed effects models were used to examine the relationship between parent-reported physical activity and outcome variables (total CMR score, triglycerides, glucose, high-density lipoprotein cholesterol, systolic blood pressure, waist circumference, weight-to-height ratio, and non-high-density lipoprotein cholesterol). Results: Data from 1885 children (6.06 y, 54.4% male) with multiple visits (n = 2670) were included in the analyses. For every unit increase of 60 minutes of PA, there was no evidence of an association with total CMR score (adjusted: −0.02 [−0.014 to 0.004], P = .11]. For the individual CMR components, there was evidence of a weak association between PA and systolic blood pressure (−0.01 [−0.03 to −0.01], P < .001) and waist-to-height ratio (−0.81 [−1.62 to −0.003], P < .001). Conclusion: Parent-reported PA among children aged 3–12 years was not statistically associated with total CMR, but was weakly associated with systolic blood pressure and waist-to-height ratio.

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