scholarly journals Management of Priapism with Chronic Myeloid Lukaemia- A Rare Presentation and Our Experiences

2020 ◽  
Vol 3 (02) ◽  
pp. 39-41
Author(s):  
Zulfia Zinat Chowdhury ◽  
Hafiz Al-Asad ◽  
Mohammad Habibur Rahman ◽  
Tamanna Bahar ◽  
Salina Haque ◽  
...  
Keyword(s):  
Chronic Myeloid Leukaemia ◽  
Emergency Management ◽  
Myeloid Leukaemia ◽  
Invasive Procedure ◽  
Minimal Invasive ◽  
Medical Emergency ◽  
Newly Diagnosed ◽  
Rare Presentation ◽  
History Of ◽  
Urological Intervention

Background: Ischaemic priapism is one of rare presentation of Chronic myeloid leukaemia due hyper viscosity and it needs urgent urological intervention. Objective: To evaluate the need of urological intervention in Priapism with Chronic Myeloid Leukaemia (CML). Methodology: This is a retrospective study from January 2014 to July 2019 in the department of Urology, DMCH. Among 126 patients 6 were diagnosed as Priapism with CML. Records of these patients were evaluated and analyzed. Results: Among 126 patients 6 patients were diagnosed as priapism with CML Mean age of the patient was 46.7 years, 2 of them were farmer and 2 had history of taking herbal drugs immediate before sexual intercourse and developed Priapism. Five patients were newly diagnosed as CML after admission in Urology ward. Of these six cases five were managed with minimal invasive procedure such as intermittent pseudo-ephedrine injection and wide bore needle corporal aspiration with pseudo-ephedrine irrigation as emergency management, only one needed surgery that was proximal shunt. After emergency management all patients were sent to hematologist for definite management of CML. Conclusion: Priapism with CML is a medical emergency which need immediate minimal intervention with concomitant haematological management.

scholarly journals Rupture Spleen as Initial Presentation in A Patient of Chronic Myeloid Leukaemia: A Case Report

2016 ◽  
Vol 13 (2) ◽  
pp. 52-54
Author(s):  
Mohammad Ibrahim Khalil ◽  
Md. Nazmul Islam ◽  
Mafruha Akter ◽  
AZM Mostaque Hossain ◽  
Md. Amir Hossain
Keyword(s):  
Chronic Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Female Student ◽  
Care Center ◽  
Chronic Phase ◽  
Abdominal Distension ◽  
Emergency Laparotomy ◽  
Rare Presentation ◽  
Health Care Center ◽  
Common Presentation

A 22 years female student presented with sudden severe abdominal pain in left upper quadrant followed by abdominal distension. She attended in surgery unit of a tertiary health care center. On examination she was in shock and the abdomen was distended, tender. She was evaluated as  surgical acute abdomen and emergency laparotomy revealed rupture of spleen and splenectomy was done. Her CBC showed gross leucocytosis with predominance of neutrophils and significant number of myelocytes and the PBF showed the features of chronic phase of chronic myeloid leukaemia. BCR-ABL was positive from bone marrow that confirms the diagnosis. Splenomegaly is a common presentation of CML. However spontaneous rupture of spleen is a very rare presentation of CML. Journal of Science Foundation, 2015;13(2):52-54DOI: http://dx.doi.org/10.3329/jsf.v13i2.27935

scholarly journals The UK SPIRIT 1 trial in newly diagnosed chronic myeloid leukaemia

2022 ◽  
Author(s):  
Paolo Gallipoli ◽  
Richard E. Clark ◽  
Jenny Byrne ◽  
Jane F. Apperley ◽  
Dragana Milojkovic ◽  
...  
Keyword(s):  
Chronic Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Newly Diagnosed ◽  
The Uk

scholarly journals Chronic myeloid leukaemia manifesting as a gynecological emergency in a young woman

2017 ◽  
Vol 6 (8) ◽  
pp. 3655
Author(s):  
Vishnupriya Padmanabhan ◽  
Mohamed M. Shahin ◽  
Karim Abdallah
Keyword(s):  
Bone Marrow ◽  
Chronic Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Young Woman ◽  
Rare Presentation ◽  
Abdominal Bleeding ◽  
Life Threatening ◽  
Laboratory Investigations ◽  
The Uk ◽  
Obvious Source

Chronic Myeloid Leukaemia (CML) is a form of blood cancer that is characterized by unregulated growth of Myeloid cells within the bone marrow. Idiopathic Spontaneous Intraperitoneal Haemorrhage (ISIH) is a rare life-threatening presentation. Case report of a young woman who presented to the emergency department with evidence of intra-abdominal bleeding. thought to be of gynaecological origin. No obvious source for the bleeding could be identified intra-operatively. Laboratory investigations showed evidence of Leukaemia which was confirmed on bone marrow biopsy. CML represents 8% of leukaemia in the UK. Despite being a rare presentation, ISIH should be considered as a possible differential diagnosis for those patients when presenting with evidence of acute abdomen.

scholarly journals Long‐term data from a phase 3 study of radotinib versus imatinib in patients with newly diagnosed, chronic myeloid leukaemia in the chronic phase (RERISE)

2020 ◽  
Vol 189 (2) ◽  
pp. 303-312 ◽  
Author(s):  
Young Rok Do ◽  
Jae‐Yong Kwak ◽  
Jeong A. Kim ◽  
Hyeoung Joon Kim ◽  
Joo Seop Chung ◽  
...  
Keyword(s):  
Chronic Myeloid Leukaemia ◽  
Myeloid Leukaemia ◽  
Chronic Phase ◽  
Newly Diagnosed ◽  
Phase 3 ◽  
Term Data
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