Comparison of Serum Lipid Profiles of Women with or Without Hormonal Contraceptives Users at a Tertiary Care Hospital in Dhaka City

Background: Both oral and injectable hormonal contraceptives are the most popular type of birth control measures used in Bangladesh. Objective: The purpose for the present study was to see the effects of hormonal contraceptives on serum lipid profiles. Methodology: This was case-control study which was carried out in the Department of Obstetrics & Gynaecology at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from July 2004 to December 2005 for eighteen (18) months. Women of reproductive age group who had given the history of taking low-dose OCP containing 30 meg EE plus 150 meg LNG were included as case group and women who were presented without the history of hormonal contraceptives use were included as control group. Blood was collected from each woman in fasting state and serum was sent for estimation of serum lipids profiles like serum triglycerides, total cholesterol, LDL and HDL. Result: The study included 40 women (control) who were not using OCP and 40 women (case) who were using OCP for more than one year. Comparison of age between control (31.75±4.85 years) and case (30.43±5.44 years) groups showed no significant difference (p>0.05). No significant difference with raised cholesterol levels (207.50±3.54 and 254.71± 45.54 mg/dl) was reported. Comparison of normal (136.16±39.46 and 154.05±35.33 mg/dl) and raised (229.00±24.52 and 246.32±35.98 mg/dl) triglyceride levels between control and case groups did not statistically significant. Comparison of normal and raised HDL levels did not show statistically any significant difference in control (32.07±3.02 mg/dL) and case (32.48±1.76 mg/dL) groups. Mean (±SD) of normal and raised levels of LDL was significantly high in case group. Normal LDL level was 82.71±26.82 and 111.05±15.40 mg/dl and raised LDL level was 138.55±3.03 and 188.82±40.37 mg/dL. Conclusion: In conclusion use of low-dose OCP containing 30 meg EE plus 150 meg LNG significantly increases serum cholesterol, serum triglyceride and LDL-cholesterol levels but not HDL-cholesterol. Journal of Science Foundation, January 2020;18(1):19-24

Aneurysmal Bone Cyst (ABC) Involving Petrous Apex Treated by Microsurgical Removal: A Case Report

Aneurysmal bone cyst (ABC) is a benign progressive expansile bone lesion that usually involves often located in vertebrae, long tubular bones and flat bones. A small percentage of aneurysmal bone cysts arise from the skull base. Skull base involvement is very rare. Here, we describe a 22-year young man presented with diplopia, right sided facial paresis and right sided sensori-neural hearing loss. CT scan and MRI showed a right petrous apex skull base mass that was confirmed as ABC in histopathology after surgical removal. Journal of Science Foundation, January 2020;18(1):25-28

Anatomical Variation of Recurrent Laryngeal Nerve with Inferior Thyroid Artery: A Cross Sectional Study in Bangladeshi People

Background: Recurrent laryngeal nerve is varied anatomically with inferior thyroid artery. Objective: The purpose of the present study was to observe the anatomical variation of recurrent laryngeal nerve with inferior thyroid artery among Bangladeshi people. Methodology: This comparative cross-sectional study was conducted in the Department of Otolaryngology and Head-Neck surgery at Sylhet MAG Osmani Medical College Hospital, Sylhet, Bangladesh from January 2004 to December 2004 for a period of one (01) year. Patients whose recurrent laryngeal nerve was identified during thyroidectomy due to various pathological conditions of thyroid gland were selected as group I. Again, the dead body which were undergone dissection were designated as group II. All the patients whose recurrent laryngeal nerve and inferior thyroid artery were identified during total, near total, sub-total, hemithyroidectomised or lobectomised were included in this study. Result: A total number of 32 patients were recruited for this study. On the left side nerve was found anteriorly in 2(10.53%), in between in 4(21.05%) and posteriorly in 13(68.42%). On the right side-nerve was found anteriorly in 7(30.43%), in between in 6(26.09%) and posteriorly in 10(43.48%). In this series nerve was seen posterior relation more than other two relations and anterior relation more on right side whereas posterior relation on left side, anterior relation more than in between relation on right side but reverse on left side. In group II On the left side nerve was found anteriorly in 2(6.25%), in between in 6(18.75%) and posteriorly in 24(75%). On the right side-nerve was found anteriorly in 8(25%), in between in 9(28.12%), and posteriorly in 10(46.88%). Conclusion: In conclusion each recurrent laryngeal nerve lies posterior to the inferior thyroid artery in the majority of the occasions whereas the nerve lies anterior to the branches of the inferior thyroid artery less commonly except right side of both study group. Journal of Science Foundation, January 2020;18(1):7-12

Impact of Climate Change in Rural Health: Bangladesh Perspective

Not Available Journal of Science Foundation, January 2020;18(1):1-2

Triterpenoids Isolated from Stem Bark of Glochidion lanceolarium (Roxb.), Voigt

This paper presents the chemical investigation of the stem barks of Glochidion lanceolarium (Roxb.) Voigt, Euphorbiaceae. Classic phytochemical investigation of organic extracts of the aerial parts of Glochidion lanceolarium together with spectroscopic methods led to the isolation and characterization of three triterpenes, namely Epilupeol (1) Glochidonol (2), Glochidone (3). Journal of Science Foundation, January 2020;18(1):13-18

Autonomic and Motor Involvement among the Patients Presented with Prolapse Lumbar Intervertebral Disc

Background: Involvement of autonomic and motor nervous system are very crucial for the patients suffering from prolapse lumbar intervertebral disc. Objective: The purpose of the present study was to see the involvement of autonomic and motor nervous system of the patients suffering from prolapse lumbar intervertebral disc. Methodology: This cross-sectional study was carried out in the department of Neurosurgery at Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from March 2006 to October 2007 for a period of one and half year. Prolapse lumbar intervertebral disc (PLID) patients who were admitted in the Department Neurosurgery at BSMMU, Dhaka, Bangladesh after clinical and radiological evaluation were selected as study population. The involvement of autonomic and motor nervous system were examined among the patients suffering from prolapse lumbar intervertebral disc. Result: A total of 59 hospital-admitted cases of PLID were included in the study. The mean age of the patients was 40.8±11.9 years and the lowest and highest ages were 21 and 65 years respectively. Majority of the patients had intact bladder function which was 57(94.9%) cases and the remaining 2(3.4%) cases had incontinence of urine. More than half (54.2%) of the subjects exhibited weak extensor hallucis longus test, while 30.5% had weak flexor digitalis longus test. Conclusion: In conclusion motor dysfunction is very high, but low rate of autonomic abnormalities are found among the patients suffering from prolapse lumbar intervertebral disc. Journal of Science Foundation, January 2020;18(1):3-6

Schwanomma of the Left Iliohypogastric Nerve: A Case Report and Technical Consideration

Schwannomas are encapsulated tumors arising from Schwann cells of the nerve sheath, and are usually solitary sporadic lesions. The schwannoma of the ilio-hypogastric nerve especially in the retro-petoneal space is very rare. We are reporting a case of the schwannoma of the left ilio-hypagastric nerve over the psoas muscle. The diagnosis was done by ultarsonogrsphy and MRI. The histopathological study confirmed the diagnosis. The tumour was excised through retro-peritoneal approach. By this approach total excision of the tumour with preservation of ilio-hypogastric nerve is possible. Journal of Science Foundation 2019;17(2):71-74

Study of Fish Diversity and Livelihood Status of Fishermen in Karatoya River, Panchagarh Region

Background: Objective: The study was conducted to investigate the fish diversity and socio-economic profiles of the fishermen of Karatoya River in Panchagarh district in the Northern part of Bangladesh. Methodology: Pertinent information was collected from forty randomly selected fishermen from the study area who were directly involved in fishing in the rivers during the period of twelve months from July 2017 to June 2018. The data interpretations showed that 50 fish species under 8 orders and 17 families were recorded from the Karatoya River during the study period. Cypriniformes was found as the most dominant order constituting 48% of the total fish populationfollowed by Channiformes (6%), Sliuriformes(18%), Clupiformes (6%), Mastacembeliformes (6%), Perciformes (12%), Beloniformes (2%), Tenaodontifomres (2%). Fishes in this river are seriously affected by the various kinds of natural and manmade causes. Under this circumstance, a better understanding of the diversity and distribution of fishes in the Karatoya River is urgently needed. Result: In the study area the fishermen age range from 16 to 65 years. It was found that most of the fishermen (35%) illiterate though a small proportion completed primary level of education. 75% percent of the fishermen used their own tube-well, while 20% and 5% used government and neighbors’ tube-well, respectively. In the study area, 55% of the fishermen were far from power plants and the rest of them had (45%) access to electricity. Majority (45%) of the fishermen was 1-10 decimal land, while 17.5% had 11-20 decimal lands and 15% had above 40 decimal lands and significant proportion of fishermen depend upon village doctors (62.5%) for their health facilities. Forty five percent of fishermen were engaged in fishing as their main occupation, 40% in agriculture and 15% in daily labor. Conclusion: Fishermen of Karatoya River were mostly illiterate, poor income, lack of training exposure and lack of awareness about their health facilities and sanitation. Journal of Science Foundation 2019;17(2):54-57

Age, Gender and Common Site of Haematoma Formation among Acute Subdural Hematoma Patients: Experience of 48 Cases in Bangladesh

Background: Acute subdural hematoma can occurs in different age group of patients in both male and female. Objective: The purpose of the present study was to observe the age and gender distribution among acute subdural hematoma patients. Methodology: This cross-sectional study was carried out in the Neurosurgery Department of Dhaka Medical College Hospital, Dhaka, Bangladesh from January 2011 to August 2012 for a period of one year and eight months. Patients with acute subdural hematoma who fulfil the inclusion criteria for surgery and got admitted were selected as study population. Acute Subdural hematoma patient of any age, both sex with GCS 5 to 13, thickness of hematoma more than l0 mm, midline shift more than 5 mm, pupil reacting to light and patient presented within 72 hours of injury were included for this study. At admission, a detailed history of the illness was taken from the patient or attendant, thorough general and neurological examinations were carried out and were recorded. Result: A total number of 48 patients were recruited for this current study. The mean age of the patients was 32.39±11.63 years and their age ranged from 10 to 56 years. The male and female ratio was 5:1. Out of 48 patients 17(31.25%) cases were fronto-temporal. Temporo-parietal were 16(33.3%) patients. Fronto-temporo-parietal were 7(14.5%) cases. Parietal were 5(10.41%) cases. Frontal were 3 (6.25%) case. Conclusion: In conclusion majority of the patients are male young adults presented with fronto-temporal and temporo-parietal region of shull. Journal of Science Foundation 2019;17(2):54-57

Antimicrobial Sensitivity Pattern of the isolated Uropathogens at a Teaching Hospital

Background: Urinary tract infection is the most common infection occurs in both male and female. Objective: This study was aimed to identify the uropathogens and their antimicrobial sensitivity pattern. Methodology: This study was carried out in the Department of Microbiology at Dhaka National Medical College & Hospital, Dhaka from January 2018 to December 2018. Result: A total of 1686 samples of urine were collected from suspected cases of urinary tract infections from Dhaka National Medical College & Hospital. Among them, 292 (17.32%) specimens showed significant bacterial growth. The most common uropathogens isolated were Escherichia coli. Conclusion: In conclusion Gram negative bacteria is the commonest uropathogens isolated. Journal of Science Foundation July 2019;17(2):42-45