Efficacy and safety of acupuncture for vascular cognitive impairment no dementia: A protocol for systematic review and meta-analysis

ABSTRACT. Background. Subcortical Vascular Cognitive Impairment (SVCI) is a clinical continuum of vascular-related cognitive impairment, including Vascular Mild Cognitive Impairment (VaMCI) and Vascular Dementia. Deficits in Executive Function (EF) are hallmarks of the disorder, but the best methods to assess this function have yet to be determined. The insidious and almost predictable course of SVCI and the multidimensional concept of EF suggest that a temporal dissociation of impairments in EF domains exists early in the disorder. Objective: This study aims to review and analyze data from the literature about performance of VaMCI patients on the most used EF tests through a meta-analytic approach. Methods: Medline, Web of Knowledge and PsycINFO were searched, using the terms: “vascular mild cognitive impairment” OR “vascular cognitive impairment no dementia” OR “vascular mild neurocognitive disorder” AND “dysexecutive” OR “executive function”. Meta-analyses were conducted for each of the selected tests, using random-effect models. Results: Systematic review showed major discrepancies among the results of the studies included. Meta-analyses evidenced poorer performance on the Trail-Making Test part B and the Stroop color test by VaMCI patients compared to controls. Conclusion: A continuum of EF impairments has been proposed in SVCI. Early deficits appear to occur in cognitive flexibility and inhibitory control.

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Chinese herbal medicine for patients with vascular cognitive impairment no dementia: protocol for a systematic review

BMJ Open ◽

10.1136/bmjopen-2015-010295 ◽

2016 ◽

Vol 6 (3) ◽

pp. e010295 ◽

Cited By ~ 5

Author(s):

Mei Feng ◽

Jingmin Lu ◽

Brian H May ◽

Shaonan Liu ◽

Xinfeng Guo ◽

...

Keyword(s):

Systematic Review ◽

Cognitive Impairment ◽

Herbal Medicine ◽

Chinese Herbal Medicine ◽

Vascular Cognitive Impairment ◽

Chinese Herbal ◽

Cognitive Impairment No Dementia

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A Systematic Review of the Definitions of Vascular Cognitive Impairment, No Dementia in Cohort Studies

Dementia and Geriatric Cognitive Disorders ◽

10.1159/000448213 ◽

2016 ◽

Vol 42 (1-2) ◽

pp. 69-79 ◽

Cited By ~ 12

Author(s):

Stephanie L. Harrison ◽

Eugene Y.H. Tang ◽

Hannah A.D. Keage ◽

John-Paul Taylor ◽

Louise Allan ◽

...

Keyword(s):

Systematic Review ◽

Cognitive Impairment ◽

Cohort Studies ◽

Daily Living ◽

Vascular Cognitive Impairment ◽

Cognitive Domain ◽

Vascular Involvement ◽

Operational Criteria ◽

Single Set ◽

Cognitive Impairment No Dementia

Background/Aims: No set operational criteria for vascular cognitive impairment, no dementia (VCI-ND) have yet been established. The aim of this study is to undertake a systematic review to compare definitions of VCI-ND that have been used in cohort studies. Methods: Medline, PsycINFO and Embase were searched from inception to October 13, 2015. Initially, 3,142 records were screened, and 30 were included in this review. Results: No single set of criteria for defining VCI-ND was identified. VCI-ND was broadly defined as an absence of dementia, cognitive impairment in at least one cognitive domain with signs of vascular involvement, and intact activities of daily living. Conclusion: Defining criteria will enable individuals with VCI-ND to be efficiently compared across cohort studies to more accurately determine the prevalence and risk of dementia.

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