scholarly journals Subcellular Fractionation of Primary Chronic Lymphocytic Leukemia Cells to Monitor Nuclear/Cytoplasmic Protein Trafficking

10.3791/60426 ◽  
2019 ◽  
Author(s):  
Jodie Hay ◽  
Michael W. Moles ◽  
Jennifer Cassels ◽  
Alison M. Michie
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Protein Trafficking ◽  
Subcellular Fractionation ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Cytoplasmic Protein ◽  
Primary Chronic Lymphocytic Leukemia

scholarly journals Interaction with Vascular Endothelium Enhances Survival in Primary Chronic Lymphocytic Leukemia Cells via NF-κB Activation and De novo Gene Transcription

2010 ◽  
Vol 70 (19) ◽  
pp. 7523-7533 ◽  
Author(s):  
Andrea G.S. Buggins ◽  
Chris Pepper ◽  
Piers E.M. Patten ◽  
Saman Hewamana ◽  
Satyen Gohil ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Gene Transcription ◽  
Vascular Endothelium ◽  
De Novo ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
De Novo Gene ◽  
Primary Chronic Lymphocytic Leukemia

scholarly journals Chemoproteomics-based kinome profiling and target deconvolution of clinical multi-kinase inhibitors in primary chronic lymphocytic leukemia cells

Leukemia ◽  
2010 ◽  
Vol 25 (1) ◽  
pp. 89-100 ◽  
Author(s):  
U Kruse ◽  
C P Pallasch ◽  
M Bantscheff ◽  
D Eberhard ◽  
L Frenzel ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Kinase Inhibitors ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Target Deconvolution ◽  
Primary Chronic Lymphocytic Leukemia

scholarly journals Genetic modification of primary chronic lymphocytic leukemia cells with a lentivirus expressing CD38

Haematologica ◽  
2010 ◽  
Vol 95 (3) ◽  
pp. 514-517 ◽  
Author(s):  
L. Pearce ◽  
L. Morgan ◽  
T. T. Lin ◽  
S. Hewamana ◽  
R. J. Matthews ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Genetic Modification ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Primary Chronic Lymphocytic Leukemia

scholarly journals Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells

Blood ◽  
2014 ◽  
Vol 123 (24) ◽  
pp. 3780-3789 ◽  
Author(s):  
Amal A. El-Mabhouh ◽  
Mary L. Ayres ◽  
Elizabeth J. Shpall ◽  
Veerabhadran Baladandayuthapani ◽  
Michael J. Keating ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Dna Synthesis ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Unscheduled Dna Synthesis ◽  
Key Points ◽  
Primary Chronic Lymphocytic Leukemia

Key Points The fludarabine and bendamustine combination is cytotoxic to CLL cells even in the presence of a protective microenvironment. H2AX activation was maximum with the combination, and unscheduled DNA synthesis induced by bendamustine was blocked by fludarabine.

scholarly journals Rapid and efficient nonviral gene delivery of CD154 to primary chronic lymphocytic leukemia cells

2005 ◽  
Vol 13 (2) ◽  
pp. 215-224 ◽  
Author(s):  
L H Li ◽  
E Biagi ◽  
C Allen ◽  
R Shivakumar ◽  
J M Weiss ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Gene Delivery ◽  
Lymphocytic Leukemia ◽  
Nonviral Gene Delivery ◽  
Leukemia Cells ◽  
Primary Chronic Lymphocytic Leukemia

scholarly journals Inflammatory cytokines and signaling pathways are associated with survival of primary chronic lymphocytic leukemia cells in vitro: a dominant role of CCL2

Haematologica ◽  
2010 ◽  
Vol 96 (3) ◽  
pp. 408-416 ◽  
Author(s):  
A. Schulz ◽  
G. Toedt ◽  
T. Zenz ◽  
S. Stilgenbauer ◽  
P. Lichter ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Signaling Pathways ◽  
Inflammatory Cytokines ◽  
Dominant Role ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Primary Chronic Lymphocytic Leukemia

Abstract 3781: The ribonucleoside analog, 8-chloro-adenosine, induces autophagy in primary chronic lymphocytic leukemia cells in vitro and in vivo

2011 ◽  
Author(s):  
Christine M. Stellrecht ◽  
Kumudha Balakrishnan ◽  
Jennifer B. Dennison ◽  
Shujun Shentu ◽  
Mary Ayres ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Primary Chronic Lymphocytic Leukemia

scholarly journals Vinblastine Rapidly Induces NOXA and Acutely Sensitizes Primary Chronic Lymphocytic Leukemia Cells to ABT-737

2013 ◽  
Vol 12 (8) ◽  
pp. 1504-1514 ◽  
Author(s):  
Darcy J.P. Bates ◽  
Alexey V. Danilov ◽  
Christopher H. Lowrey ◽  
Alan Eastman
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Lymphocytic Leukemia ◽  
Leukemia Cells ◽  
Primary Chronic Lymphocytic Leukemia
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