SUCCESFUL TREATMENT OF POSTOPERATİVE ATELECTASİS WİTH DORNASE ALPHA (PULMOZYME®) AFTER CONGENİTAL HEART SURGERY İN A NEWBORN

2021 ◽  
Author(s):  
Ahmet ÖZYAZICI ◽  
Nurdan DİNLEN FETTAH ◽  
Rumeysa ÇİTLİ ◽  
Ahmet ÖKTEM ◽  
Ayşegül ZENCİROĞLU
Keyword(s):  
Congenital Heart ◽  
Heart Surgery ◽  
Congenital Heart Surgery ◽  
Dornase Alpha ◽  
Postoperative Atelectasis

scholarly journals SUCCESFUL TREATMENT OF POSTOPERATİVE ATELECTASİS WİTH DORNASE ALPHA (PULMOZYME) AFTER CONGENİTAL HEART SURGERY İN A NEWBORN

CHEST Journal ◽  
2020 ◽  
Vol 157 (6) ◽  
pp. A37 ◽  
Author(s):  
N. Dinlen Fettah ◽  
A. Özyazici ◽  
R. Çitli ◽  
A. Zenciroğlu
Keyword(s):  
Congenital Heart ◽  
Heart Surgery ◽  
Congenital Heart Surgery ◽  
Dornase Alpha ◽  
Postoperative Atelectasis

scholarly journals Treatment Of Postoperative Atelectasis With Dornase Alpha (Pulmozyme®) After Congenital Heart Surgery

2015 ◽  
Vol 2 (4) ◽  
Author(s):  
Mustafa Hakan Zor ◽  
Abdullah Ozer ◽  
Huseyin Demirtas ◽  
Yigit Kilic ◽  
Baris Mardin
Keyword(s):  
Congenital Heart ◽  
Heart Surgery ◽  
Congenital Heart Surgery ◽  
Dornase Alpha ◽  
Postoperative Atelectasis

The use of dornase alpha for post-operative pulmonary atelectasis after congenital heart surgery

2013 ◽  
Vol 24 (5) ◽  
pp. 807-812 ◽  
Author(s):  
Erkut Ozturk ◽  
Ibrahim C. Tanidir ◽  
Sertac Haydin ◽  
Ismihan S. Onan ◽  
Ender Odemis ◽  
...  
Keyword(s):  
Congenital Heart ◽  
Heart Surgery ◽  
Congenital Heart Surgery ◽  
Chest Physiotherapy ◽  
Control Group ◽  
Study Group ◽  
Care Hospital ◽  
Pulmonary Atelectasis ◽  
Median Period ◽  
Dornase Alpha

AbstractObjective: To investigate the efficacy of dornase alpha, a mucolytic agent, in children who developed pulmonary atelectasis after congenital heart surgery. Design: Retrospective case–control study. Setting: Paediatric cardiac intensive care unit at a tertiary care hospital. Patients: Between July, 2011 and July, 2012, 41 patients who underwent congenital cardiac operations and developed post-operative pulmonary atelectasis that was resistant to conventional treatment and chest physiotherapy. Interventions: In all, 26 patients received dornase alpha treatment. As a control group, 15 patients were treated with conventional medications and chest physiotherapy. Main results: The median age of patients was 25.5 (3–480) days in the study group and 50.0 (3–480) days in the control group. A total of 15 (57.6%) patients in the study group and 8 (53.3%) patients in the control group were male. The median weight was 4.2 (2.9–14.2) kg and 4.0 (3.5–13.6) kg in the study and control group, respectively. In the study group, pulmonary atelectasis was diagnosed at a median period of 5 (2–18) days after operations, whereas in the control group atelectasis was diagnosed at a median period of post-operative 6 (3–19) days. In the study group, the median atelectasis score decreased from 3.4 (1–6) to 0.8 (0–3) (p = 0.001). The median pO2 level increased from 69 (17–142) mmHg to 89 (30–168) mmHg (p = 0.04). In addition, heart rate and respiratory rate per minute were significantly decreased (p < 0.05). There were no significant changes in these parameters in the control group. Conclusions: The use of dornase alpha can be effective for the management of pulmonary atelectasis that develops following congenital heart surgery.

Care Models and Associated Outcomes in Congenital Heart Surgery

PEDIATRICS ◽  
2011 ◽  
Vol 127 (6) ◽  
pp. peds.2010-2796d-peds.2010-2796d
Keyword(s):  
Congenital Heart ◽  
Heart Surgery ◽  
Congenital Heart Surgery ◽  
Care Models

scholarly journals LONG-TERM TRANSPLANT-FREE SURVIVAL AFTER CONGENITAL HEART SURGERY

2021 ◽  
Vol 77 (18) ◽  
pp. 481
Author(s):  
Lazaros Kochilas ◽  
Amanda Thomas ◽  
Chao Zhang ◽  
J’Neka Claxton ◽  
Courtney McCracken ◽  
...  
Keyword(s):  
Congenital Heart ◽  
Heart Surgery ◽  
Congenital Heart Surgery ◽  
Free Survival

Early Extubation in a Pediatric Cardiac Surgery Program Located at High Altitude

2021 ◽  
Vol 12 (4) ◽  
pp. 473-479
Author(s):  
Orlando José Tamariz-Cruz ◽  
Luis Antonio García-Benítez ◽  
Hector Díliz-Nava ◽  
Felipa Acosta-Garduño ◽  
Marcela Barrera-Fuentes ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Operating Room ◽  
Sea Level ◽  
Congenital Heart ◽  
Heart Surgery ◽  
Anesthetic Management ◽  
Fontan Procedure ◽  
Congenital Heart Surgery ◽  
Serum Lactate ◽  
Early Extubation

Background: Early extubation is performed either in the operating room or in the cardiovascular intensive care unit during the first 24 postoperative hours; however, altitude might possibly affect the process. The aim of this study is the evaluation of early extubation feasibility of patients undergoing congenital heart surgery in a center located at 2,691 m (8,828 ft.) above sea level. Material and Methods: Patients undergoing congenital heart surgery, from August 2012 through December 2018, were considered for early extubation. The following variables were recorded: weight, serum lactate, presence or not of Down syndrome, optimal oxygenation and acid–base status according to individual physiological condition (biventricular or univentricular), age, bypass time, and ventricular function. Standardized anesthetic management with dexmedetomidine–fentanyl–rocuronium and sevoflurane was used. If extubation in the operating room was considered, 0.08 mL/kg of 0.5% ropivacaine was injected into the parasternal intercostal spaces bilaterally before closing the sternum. Results: Four hundred seventy-eight patients were operated and 81% were early extubated. Mean pre- and postoperative SaO2 was 92% and 98%; postoperative SaO2 for Glenn and Fontan procedures patients was 82% and 91%, respectively. Seventy-three percent of patients who underwent Glenn procedure, 89% of those who underwent Fontan procedure (all nonfenestrated), and 85% with Down syndrome were extubated in the operating room. Reintubation rate in early extubated patients was 3.6%. Conclusion: Early extubation is feasible, with low reintubation rates, at 2,691 m (8,828 ft.) above sea level, even in patients with single ventricle physiology.

Variables Prevalent Among Early Unplanned Readmissions in Infants Following Congenital Heart Surgery

2021 ◽  
Author(s):  
Anna E. Berry ◽  
Nancy S. Ghanayem ◽  
Danielle Guffey ◽  
Meghan Anderson ◽  
Jeffrey S. Heinle ◽  
...  
Keyword(s):  
Congenital Heart ◽  
Heart Surgery ◽  
Congenital Heart Surgery
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