Fine-scale mapping in Neurospora crassa by using genome-wide knockout strains

Mycologia ◽  
2012 ◽  
Vol 104 (1) ◽  
pp. 321-323 ◽  
Author(s):  
Thomas M. Hammond ◽  
David G. Rehard ◽  
Bryant C. Harris ◽  
Patrick K.T. Shiu
Keyword(s):  
Neurospora Crassa ◽  
Fine Scale ◽  
Genome Wide ◽  
Fine Scale Mapping

scholarly journals Fine-scale mapping of meiotic recombination in Asians

BMC Genetics ◽  
2013 ◽  
Vol 14 (1) ◽  
pp. 19 ◽  
Author(s):  
Thomas Bleazard ◽  
Young Seok Ju ◽  
Joohon Sung ◽  
Jeong-Sun Seo
Keyword(s):  
Meiotic Recombination ◽  
Fine Scale ◽  
Fine Scale Mapping

Fine‐scale mapping of deep‐sea habitat‐forming species densities reveals taxonomic specific environmental drivers

2021 ◽  
Author(s):  
Jennifer A. Dijkstra ◽  
Kristen Mello ◽  
Derek Sowers ◽  
Mashkoor Malik ◽  
Les Watling ◽  
...  
Keyword(s):  
Deep Sea ◽  
Environmental Drivers ◽  
Fine Scale ◽  
Fine Scale Mapping

scholarly journals Fine-Scale Mapping of the 4q24 Locus Identifies Two Independent Loci Associated with Breast Cancer Risk

2015 ◽  
Vol 24 (11) ◽  
pp. 1680-1691 ◽  
Author(s):  
Xingyi Guo ◽  
Jirong Long ◽  
Chenjie Zeng ◽  
Kyriaki Michailidou ◽  
Maya Ghoussaini ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Fine Scale ◽  
Fine Scale Mapping

The details are in the genome-wide SNPs: fine scale evolution of the Malaysian weedy rice

Plant Science ◽  
2021 ◽  
pp. 110985
Author(s):  
Maggie Pui San Sudo ◽  
Rupini Yesudasan ◽  
Ting Xiang Neik ◽  
Dilipkumar Masilamany ◽  
Jayasyaliny Jayaraj ◽  
...  
Keyword(s):  
Weedy Rice ◽  
Fine Scale ◽  
Genome Wide ◽  
Scale Evolution

scholarly journals Fine-scale mapping in case-control samples using locus scoring and haplotype-sharing methods

BMC Genetics ◽  
2005 ◽  
Vol 6 (Suppl 1) ◽  
pp. S74 ◽  
Author(s):  
Keith Humphreys ◽  
Mark M Iles
Keyword(s):  
Case Control ◽  
Fine Scale ◽  
Haplotype Sharing ◽  
Fine Scale Mapping ◽  
Control Samples

scholarly journals A Light-Inducible Strain for Genome-Wide Histone Turnover Profiling in Neurospora crassa

Genetics ◽  
2020 ◽  
Vol 215 (3) ◽  
pp. 569-578
Author(s):  
William K. Storck ◽  
Sabrina Z. Abdulla ◽  
Michael R. Rountree ◽  
Vincent T. Bicocca ◽  
Eric U. Selker
Keyword(s):  
Neurospora Crassa ◽  
Histone H3 ◽  
Chromatin Accessibility ◽  
Histone Octamer ◽  
Genome Wide ◽  
Incubation Periods ◽  
Mutant Strains ◽  
Functional Consequences ◽  
Dynamic Structures ◽  
Histone Exchange

In chromatin, nucleosomes are composed of ∼146 bp of DNA wrapped around a histone octamer, and are highly dynamic structures subject to remodeling and exchange. Histone turnover has previously been implicated in various processes including the regulation of chromatin accessibility, segregation of chromatin domains, and dilution of histone marks. Histones in different chromatin environments may turnover at different rates, possibly with functional consequences. Neurospora crassa sports a chromatin environment that is more similar to that of higher eukaryotes than yeasts, which have been utilized in the past to explore histone exchange. We constructed a simple light-inducible system to profile histone exchange in N. crassa on a 3xFLAG-tagged histone H3 under the control of the rapidly inducible vvd promoter. After induction with blue light, incorporation of tagged H3 into chromatin occurred within 20 min. Previous studies of histone turnover involved considerably longer incubation periods and relied on a potentially disruptive change of medium for induction. We used this reporter to explore replication-independent histone turnover at genes and examine changes in histone turnover at heterochromatin domains in different heterochromatin mutant strains. In euchromatin, H3-3xFLAG patterns were almost indistinguishable from that observed in wild-type in all mutant backgrounds tested, suggesting that loss of heterochromatin machinery has little effect on histone turnover in euchromatin. However, turnover at heterochromatin domains increased with loss of trimethylation of lysine 9 of histone H3 or HP1, but did not depend on DNA methylation. Our reporter strain provides a simple yet powerful tool to assess histone exchange across multiple chromatin contexts.

Genome-wide SNPs reveal complex fine scale population structure in the California market squid fishery (Doryteuthis opalescens)

2020 ◽  
Author(s):  
Samantha H. Cheng ◽  
Mark Gold ◽  
Nichole Rodriguez ◽  
Paul H. Barber
Keyword(s):  
Population Structure ◽  
Fine Scale ◽  
Genome Wide ◽  
Doryteuthis Opalescens ◽  
Scale Population
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