Up-regulation of p53 by antisense expression of HPV18 E6 oncogene does not influence the level of MN/CA IX tumor-associated protein in HeLa cervical carcinoma cells.

1998 ◽  
Author(s):  
J Lieskovská ◽  
M Kaluzova ◽  
R Opavsky ◽  
S Kaluz ◽  
J Pastorek ◽  
...  
Keyword(s):  
Cervical Carcinoma ◽  
Carcinoma Cells ◽  
Antisense Expression ◽  
Ca Ix ◽  
Hpv18 E6

scholarly journals Reduction of syndecan-1 mRNA in cervical-carcinoma cells is involved with the 3? untranslated region

1999 ◽  
Vol 80 (4) ◽  
pp. 527-532 ◽  
Author(s):  
Kazuyoshi Nakanishi ◽  
Naohisa Yoshioka ◽  
Kiyomasa Oka ◽  
Akira Hakura
Keyword(s):  
Cervical Carcinoma ◽  
Untranslated Region ◽  
Carcinoma Cells

Nevirapine induces growth arrest and premature senescence in human cervical carcinoma cells

2008 ◽  
Vol 111 (2) ◽  
pp. 344-349 ◽  
Author(s):  
Konstantinos Stefanidis ◽  
Dimitris Loutradis ◽  
Leandros-Vassilios Vassiliou ◽  
Vasiliki Anastasiadou ◽  
Erasmia Kiapekou ◽  
...  
Keyword(s):  
Cervical Carcinoma ◽  
Growth Arrest ◽  
Carcinoma Cells ◽  
Premature Senescence ◽  
Human Cervical Carcinoma ◽  
Human Cervical Carcinoma Cells

EFFECTS OF PHOTODYNAMIC THERAPY MEDIATED BY EMODIN IN CERVICAL CARCINOMA CELLS

2021 ◽  
pp. 102394
Author(s):  
Ana Emília Brumatti Galiardi-Campoy ◽  
Francielly Cristina Machado ◽  
Tamara Carvalho ◽  
Antonio Claudio Tedesco ◽  
Paula Rahal ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cervical Carcinoma ◽  
Carcinoma Cells

scholarly journals The anti-proliferative effects and mechanisms of low molecular weight scorpion BmK venom peptides on human hepatoma and cervical carcinoma cells in vitro

2014 ◽  
Vol 8 (4) ◽  
pp. 1581-1584 ◽  
Author(s):  
WEILING LI ◽  
YI XIN ◽  
YANG CHEN ◽  
XINLI LI ◽  
CUILI ZHANG ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Cervical Carcinoma ◽  
Carcinoma Cells ◽  
Low Molecular Weight ◽  
Human Hepatoma ◽  
Venom Peptides

scholarly journals The Effects of miR-195-5p/MMP14 on Proliferation and Invasion of Cervical Carcinoma Cells Through TNF Signaling Pathway Based on Bioinformatics Analysis of Microarray Profiling

2018 ◽  
Vol 50 (4) ◽  
pp. 1398-1413 ◽  
Author(s):  
Min Li ◽  
Chun-Xia Ren ◽  
Jian-Mei Zhang ◽  
Xiao-Yan Xin ◽  
Teng Hua ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Signaling Pathway ◽  
Microarray Analysis ◽  
Cervical Carcinoma ◽  
Carcinoma Cells ◽  
Gene Set Enrichment Analysis ◽  
Qrt Pcr ◽  
In Vivo Experiment ◽  
Proliferation And Invasion

Background/Aims: This study is aimed at identification of miR-195-5p/MMP14 expression in cervical cancer (CC) and their roles on cell proliferation and invasion profile of CC cells through TNF signaling pathway in CC. Methods: Microarray analysis, gene set enrichment analysis (GSEA) and DAVID were used to analyze differentially expressed miRNAs, mRNAs and signaling pathways. MiR-195-5p and MMP14 expression levels in CC cell were determined by qRT-PCR. Western blot was employed to measure MMP14 and TNF signaling pathway-relating protein level. Luciferase reporter system was used to confirm the targeting relationship between MMP14 and miR-195-5p. Cell proliferation and invasion was respectively deeded by CCK8, transwell. In vivo experiment was carried out to study the impact of MMP14 and miR-195-5p on CC development in mice. Results: The microarray analysis and the results of qRT-PCR determined that miR-195-5p was under-expressed and MMP14 was over-expressed in CC cells. GSEA and DAVID analysis showed that TNF signaling pathway was regulated by miR-195-5p/MMP14 and activated in cervical carcinoma cells. The miR-195-5p and MMP14 have a negative regulation relation. In vivo experiment found that down-regulated MMP14 and up-regulated miR-195-5p suppressed the tumor development. Conclusion: Our results suggest that MMP14 is a direct target of miR-195-5p, and down-regulated MMP14 and up-regulated miR-195-5p suppressed proliferation and invasion of CC cells by inhibiting TNF signaling pathway.

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