Novel epi-virotherapeutic treatment of pancreatic cancer combining the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus

International Journal of Oncology ◽

10.3892/ijo.2016.3675 ◽

2016 ◽

Vol 49 (5) ◽

pp. 1931-1944 ◽

Author(s):

Tim Patrick Ellerhoff ◽

Susanne Berchtold ◽

Sascha Venturelli ◽

Markus Burkard ◽

Irina Smirnow ◽

...

Keyword(s):

Pancreatic Cancer ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Vaccine Virus ◽

Measles Vaccine ◽

Deacetylase Inhibitor

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Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma

Molecular Therapy — Oncolytics ◽

10.1038/mto.2015.19 ◽

2015 ◽

Vol 2 ◽

pp. 15019 ◽

Author(s):

Benjamin Ruf ◽

Susanne Berchtold ◽

Sascha Venturelli ◽

Markus Burkard ◽

Irina Smirnow ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Vaccine Virus ◽

Measles Vaccine ◽

Deacetylase Inhibitor

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Combination of the oral histone deacetylase inhibitor resminostat with oncolytic measles vaccine virus as a new option for epi-virotherapeutic treatment of hepatocellular carcinoma (HCC)

Zeitschrift für Gastroenterologie ◽

10.1055/s-0035-1559268 ◽

2015 ◽

Vol 53 (08) ◽

Author(s):

B Ruf ◽

S Berchtold ◽

S Venturelli ◽

I Smirnow ◽

T Prenzel ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Vaccine Virus ◽

Measles Vaccine ◽

Deacetylase Inhibitor

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Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells

International Journal of Cancer ◽

10.1002/ijc.22558 ◽

2007 ◽

Vol 121 (3) ◽

pp. 656-665 ◽

Author(s):

Takashi Kumagai ◽

Naoki Wakimoto ◽

Dong Yin ◽

Sigal Gery ◽

Norihiko Kawamata ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Hydroxamic Acid ◽

Human Pancreatic Cancer ◽

Suberoylanilide Hydroxamic Acid ◽

Pancreatic Cancer Cells ◽

Deacetylase Inhibitor

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Abstract 203: The histone deacetylase inhibitor LBH589 sensitizes pancreatic cancer cells to TRAIL-induced apoptosis through induction of c-FLIP degradation

10.1158/1538-7445.am10-203 ◽

2010 ◽

Author(s):

John Kauh ◽

Songqing Fan ◽

Lily Yang ◽

Fadlo R. Khuri ◽

Shi-Yong Sun

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Pancreatic Cancer Cells ◽

Deacetylase Inhibitor ◽

Induced Apoptosis

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FR901228, a novel histone deacetylase inhibitor, induces cell cycle arrest and subsequent apoptosis in refractory human pancreatic cancer cells

International Journal of Oncology ◽

10.3892/ijo.24.3.679 ◽

2004 ◽

Author(s):

Nariatsu Sato ◽

Tetsuo Ohta ◽

Hirohisa Kitagawa ◽

Masato Kayahara ◽

Itasu Ninomiya ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cell Cycle Arrest ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Human Pancreatic Cancer ◽

Cycle Arrest ◽

Pancreatic Cancer Cells ◽

Deacetylase Inhibitor

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Growth inhibition of pancreatic cancer cells by histone deacetylase inhibitor belinostat through suppression of multiple pathways including HIF, NFkB, and mTOR signaling in vitro and in vivo

Molecular Carcinogenesis ◽

10.1002/mc.22024 ◽

2013 ◽

Vol 53 (9) ◽

pp. 722-735 ◽

Author(s):

Wenwen Chien ◽

Dhong Hyun Lee ◽

Yun Zheng ◽

Peer Wuensche ◽

Rosie Alvarez ◽

...

Keyword(s):

Pancreatic Cancer ◽

Growth Inhibition ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Mtor Signaling ◽

Pancreatic Cancer Cells ◽

Deacetylase Inhibitor

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Effects of a histone deacetylase inhibitor, sodium butyrate, on 53-kDa protein expression and sensitivity to anticancer drugs of pancreatic cancer cells

Current Therapeutic Research ◽

10.1016/j.curtheres.2010.06.002 ◽

2010 ◽

Vol 71 (3) ◽

pp. 162-172 ◽

Author(s):

Masaki Kitazono ◽

Hiroyuki Shinchi ◽

Sumiya Ishigami ◽

Shinichi Ueno ◽

Shoji Natsugoe

Keyword(s):

Pancreatic Cancer ◽

Protein Expression ◽

Cancer Cells ◽

Histone Deacetylase ◽

Anticancer Drugs ◽

Sodium Butyrate ◽

Histone Deacetylase Inhibitor ◽

Pancreatic Cancer Cells ◽

Deacetylase Inhibitor

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Suppression of Tumor Growth and Muscle Wasting in a Transgenic Mouse Model of Pancreatic Cancer by the Novel Histone Deacetylase Inhibitor AR-42

Neoplasia ◽

10.1016/j.neo.2016.10.003 ◽

2016 ◽

Vol 18 (12) ◽

pp. 765-774 ◽

Author(s):

Sally E. Henderson ◽

Li-Yun Ding ◽

Xiaokui Mo ◽

Tanios Bekaii-Saab ◽

Samuel K. Kulp ◽

...

Keyword(s):

Pancreatic Cancer ◽

Mouse Model ◽

Tumor Growth ◽

Transgenic Mouse ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Muscle Wasting ◽

Transgenic Mouse Model ◽

The Novel ◽

Deacetylase Inhibitor

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Histone deacetylase inhibitor augments anti-tumor effect of gemcitabine and pegylated interferon-α on pancreatic cancer cells

International Journal of Clinical Oncology ◽

10.1007/s10147-011-0246-y ◽

2011 ◽

Vol 16 (6) ◽

pp. 671-678 ◽

Author(s):

Shuichi Iwahashi ◽

Mitsuo Shimada ◽

Tohru Utsunomiya ◽

Yuji Morine ◽

Satoru Imura ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Pegylated Interferon ◽

Interferon Α ◽

Pancreatic Cancer Cells ◽

Deacetylase Inhibitor

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Abstract 5065: Harnessing epigenetic reprogramming by histone deacetylase inhibitor MS275 for pancreatic cancer therapy

10.1158/1538-7445.am2017-5065 ◽

2017 ◽

Author(s):

Gaoyang Liang ◽

Ruth Yu ◽

Christopher Liddle ◽

Morgan Truitt ◽

Corina Antal ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Therapy ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitor ◽

Epigenetic Reprogramming ◽

Deacetylase Inhibitor ◽

Pancreatic Cancer Therapy

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