A CASE OF MEMBRANOUS NEPHROPATHY IN WHICH GASTRECTOMY FOR A GASTRIC CANCER LED TO A REMISSION OF NEPHROTIC SYNDROME

1997 ◽  
Vol 58 (8) ◽  
pp. 1864-1868 ◽  
Author(s):  
Kentaro EMOTO ◽  
Tadateru TAKAHASHI ◽  
Yoshitaka KATO ◽  
Takayuki NOMIMURA ◽  
Ichiro OMORI ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Nephrotic Syndrome ◽  
Membranous Nephropathy

Nephrotic syndrome secondary to alpha-1 antitrypsin deficiency

2021 ◽  
Vol 14 (3) ◽  
pp. e240288
Author(s):  
Gabriela F Santos ◽  
Paul Ellis ◽  
Daniela Farrugia ◽  
Alice M Turner
Keyword(s):  
Nephrotic Syndrome ◽  
Membranous Nephropathy ◽  
Clinical Investigation ◽  
Genetic Disorder ◽  
Clinical Manifestations ◽  
Protective Role ◽  
Caucasian Woman ◽  
Antitrypsin Deficiency ◽  
Alpha 1 Antitrypsin Deficiency ◽  
Alpha 1 Antitrypsin

We report a 64-year-old caucasian woman diagnosed with membranous nephropathy secondary to alpha-1 antitrypsin deficiency (AATD). AATD is a rare autosomal codominant genetic disorder. Its clinical manifestations are mostly observed in the lungs, with early-onset emphysema. Nephropathy due to AATD is still very rare and only a few cohort studies have been reported. It has been recognised that alpha-1 antitrypsin has a protective role in the kidneys which enhances the possibility of development of kidney failure, such as nephrotic syndrome, in cases of AATD. Further clinical investigation is needed to understand the relationship between the development of nephropathy, namely membranous nephropathy, and AATD.

scholarly journals The Gastrectomy for a Gastric Cancer Led to a Remission of Nephrotic Syndrome: A Case Report

2004 ◽  
Vol 37 (11) ◽  
pp. 1727-1731 ◽  
Author(s):  
Tadafumi Asaoka ◽  
Shigeo Matsui ◽  
Takashi Iwazawa ◽  
Yutaka Kimura ◽  
Toshiyuki Kano ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Nephrotic Syndrome ◽  
Case Report

Effect of Prolonged Tacrolimus Treatment in Idiopathic Membranous Nephropathy with Nephrotic Syndrome

Pharmacology ◽  
2013 ◽  
Vol 91 (5-6) ◽  
pp. 259-266 ◽  
Author(s):  
Hang Yuan ◽  
Nian Liu ◽  
Guang-Dong Sun ◽  
Ye Jia ◽  
Ping Luo ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Membranous Nephropathy ◽  
Idiopathic Membranous Nephropathy

Membranous nephropathy

2010 ◽  
pp. 3985-3988
Author(s):  
Dwomoa Adu
Keyword(s):  
Prostate Cancer ◽  
Systemic Lupus Erythematosus ◽  
Nephrotic Syndrome ◽  
Basement Membrane ◽  
Autoimmune Diseases ◽  
Outer Surface ◽  
Glomerular Basement Membrane ◽  
Lupus Erythematosus ◽  
Membranous Nephropathy ◽  
Systemic Lupus

Membranous nephropathy, which accounts for 20 to 30% of cases of the nephrotic syndrome in adults, is defined histologically by the presence of subepithelial immune deposits on the outer surface of the glomerular basement membrane. The immune mechanisms that lead to this are uncertain, and most cases are of unknown cause (idiopathic), but the condition can be associated with autoimmune diseases (systemic lupus erythematosus), malignancy (in 10% of cases, most commonly lung and prostate cancer), drugs, and infections....

Dysbiosis of gut microbiota in adult idiopathic membranous nephropathy with nephrotic syndrome

2020 ◽  
Vol 147 ◽  
pp. 104359 ◽  
Author(s):  
Jun Zhang ◽  
Dan Luo ◽  
Zhiming Lin ◽  
Wenying Zhou ◽  
Jialing Rao ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Gut Microbiota ◽  
Membranous Nephropathy ◽  
Idiopathic Membranous Nephropathy

scholarly journals Acquired von Willebrand Syndrome Complicating Nephrotic Syndrome: A Case of a Patient With Membranous Nephropathy

2018 ◽  
Vol 11 ◽  
pp. 117954761876337
Author(s):  
Taro Sugase ◽  
Tetsu Akimoto ◽  
Takaaki Kimura ◽  
Takashi Yagisawa ◽  
Eiji Kusano ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Membranous Nephropathy ◽  
Major Trauma ◽  
Invasive Procedure ◽  
Bleeding Risk ◽  
Current Case ◽  
Acquired Von Willebrand Syndrome ◽  
Active Partial Thromboplastin Time ◽  
Von Willebrand ◽  
Prompt Diagnosis

Acquired von Willebrand syndrome (AVWS) is a rare clinical entity presenting with heterogeneous hemorrhagic manifestations, although some subsets of patients with AVWS may be asymptomatic until they are exposed to major trauma, an invasive procedure, or surgery. We herein report one such case in a 73-year-old male patient with nephrotic syndrome with a prolonged active partial thromboplastin time. We initially did not deal with this distinct abnormal clotting profile seriously, but persistent bleeding after a retroperitoneoscopic-assisted renal biopsy that allowed us to ascribe his nephrotic syndrome to membranous nephropathy fortuitously led to the discovery of concurrent AVWS. We feel that an accurate and prompt diagnosis as well as awareness of the disease remain a challenge for physicians and therefore strongly recommend the further accumulation of experiences similar to our own in a prospective manner. This report underscores the pitfalls associated with determining the bleeding risk, including an insufficient assessment and improper weighting of an abnormal clotting profile prior to the invasive procedure. Several management concerns that emerged in the current case are also discussed.

scholarly journals The Unpredictability of Idiopathic Membranous Nephropathy: An Illustrative Case Report

2018 ◽  
Vol 8 (2) ◽  
pp. 103-106
Author(s):  
Murray L. Levin ◽  
Shubhada Ahya
Keyword(s):  
Nephrotic Syndrome ◽  
Case Report ◽  
Complete Remission ◽  
Female Patient ◽  
Membranous Nephropathy ◽  
Low Dose ◽  
Conservative Therapy ◽  
Current Knowledge ◽  
Illustrative Case ◽  
Cytomegalovirus Colitis

The case of a female patient with primary membranous nephropathy is presented. She was treated with corticosteroids and chlorambucil after conservative therapy had failed and went into remission for 5 years. Her nephrotic syndrome recurred but did not respond to the same regimen. She had another complete remission after treatment with corticosteroids and cyclosporine, but the nephrosis recurred after 7 years. Again, she failed to respond with retreatment of steroids plus cyclosporine. She was treated with alternate-day steroid plus mycophenolate and, once again, had a complete remission. She was maintained on low-dose mycophenolate for 7 more years. The mycophenolate had to be discontinued because of cytomegalovirus colitis. Treatment with ganciclovir abolished the colitis. She is still in remission 10 years later. The case is discussed with regard to current knowledge of the immune pathogenesis of membranous nephropathy as well as the unknowns of the immunogenesis of the disease.

Sign in / Sign up

Export Citation Format

Share Document