Crevicular Alkaline Phosphatase Activity During Orthodontic Tooth Movement: Canine Retraction Stage

2008 ◽  
Vol 8 (3) ◽  
pp. 228-233 ◽  
Author(s):  
A.A. A. Asma ◽  
M.A. W. Rohaya ◽  
Z.A. Shahrul Hi
2002 ◽  
Vol 122 (5) ◽  
pp. 548-556 ◽  
Author(s):  
Giuseppe Perinetti ◽  
Michele Paolantonio ◽  
Michele D'Attilio ◽  
Domenico D'Archivio ◽  
Domenico Tripodi ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Rohaya Megat Abdul Wahab ◽  
Maryati Md Dasor ◽  
Sahidan Senafi ◽  
Asma Alhusna Abang Abdullah ◽  
Zulham Yamamoto ◽  
...  

Purpose. This study is aimed to compare the effects of two different orthodontic forces on crevicular alkaline phosphatase activity, rate of tooth movement, and root resorption.Materials and Methods. Twelve female subjects of class II division 1 malocclusion participated. Maxillary canines with bonded fixed appliances acted as the tested teeth, while their antagonists with no appliances acted as the controls. Canine retraction was performed using nickel titanium coil spring that delivered forces of 100 gm or 150 gm to either side. Crevicular fluid was analyzed for ALP activity, and study models were casted to measure tooth movements. Root resorption was assessed using periapical radiographs before and after the force application.Results. ALP activity at the mesial sites peaked at week 1 for 150 gm group with significant differences when compared with the 100 gm group. Cumulative canine movements were significantly greater in the 150 gm force (2.10±0.50 mm) than in the 100 gm force (1.57±0.44 mm). No root resorption was in the maxillary canines after retraction.Conclusions. A force of 150 gm produced faster tooth movements and higher ALP activity compared with the 100 gm group and had no detrimental effects such as root resorption.


2017 ◽  
Vol 16 (2) ◽  
Author(s):  
Ainuddin Yushar Yusof ◽  
Rohaya Megat Abdul Wahab ◽  
Shahrul Hisham Zainal Ariffin ◽  
Sahidan Senafi ◽  
Maryati Abdul Rahman

Introduction: Orthodontic tooth movement is a complex process involving tooth and periodontal tissue, which release enzymes and biomarkers. The aim of this study was to investigate enzymes activities of salivary fluid during orthodontic treatment. Materials and Methods: A group of nineteen healthy subject (mean age 21.5 years) with Class II/1 malocclusion who required extraction of maxillary first premolar were recruited. Saliva samples were collected from these 19 patients that underwent canine traction using fixed appliances. Enzymes activities were measured before placement of fixed appliances (basal activity) followed with immediately before and weekly canine retraction for five weeks. The specific Lactate Dehydrogenase (LDH), Aspartate Aminotransferase (AST), Tartrate Resistance Acid Phosphatase (TRAP) and Alkaline Phosphatase (ALP) activities in saliva sample were analyzed using spectrophotometer (405nm). Result: No statistical significant (p> 0.05) difference was noted in LDH activity between basal activity and during canine retraction period. AST showed higher activity compared to basal activity from week 0 to week 1 with statistically significant increased (p<0.05) found in week 1. ALP showed significantly higher enzyme activity compared to basal activity from week 1 to 5, with the peak level at week 5. While TRAP showed significant increase in enzyme activity compared to basal activity only at week 2 after canine retraction. Conclusion(s):  Orthodontic tooth movement can be monitored through the expression of AST, TRAP and ALP activity in saliva. Saliva LDH cannot be used as a biomarker in monitoring tooth movement.


1960 ◽  
Vol XXXV (IV) ◽  
pp. 575-584 ◽  
Author(s):  
C. Borel ◽  
J. Frei ◽  
A. Vannotti

ABSTRACT Enzymatic studies, on leucocytes of pregnant women, show an increase of the alkaline phosphatase activity and a decrease of the glucose consumption and lactate production, as well as of proteolysis. The oxygen consumption, with succinate as substrate, does not vary.


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