Relationship between Angiotensinogen gene T174M Polymorphism and Essential Hypertension in a Sample of Algerian Population: Case Control Study

2014 ◽  
Vol 14 (4) ◽  
pp. 168-173 ◽  
Author(s):  
Asma Amrani ◽  
F. Mesli Tale ◽  
M.B. Baba Hamed
Keyword(s):  
Essential Hypertension ◽  
Case Control Study ◽  
Case Control ◽  
Angiotensinogen Gene ◽  
Algerian Population ◽  
T174m Polymorphism ◽  
Control Study

scholarly journals Risk factors for the development of essential hypertension in a Mongolian population of China: a case-control study

2014 ◽  
Vol 13 (2) ◽  
pp. 3283-3291 ◽  
Author(s):  
N. Dalai ◽  
H. Cui ◽  
M. Yan ◽  
G. Rile ◽  
S. Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Essential Hypertension ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Genetic association study of prolylcarboxypeptidase polymorphisms with susceptibility to essential hypertension in the Yi minority of China: A case–control study based on an isolated population

2020 ◽  
Vol 21 (2) ◽  
pp. 147032032091958 ◽  
Author(s):  
Yanrui Wu ◽  
Hongju Yang ◽  
Chunjie Xiao
Keyword(s):  
Essential Hypertension ◽  
Case Control Study ◽  
Strong Association ◽  
Case Control ◽  
Negative Regulator ◽  
Mountainous Area ◽  
Nucleotide Polymorphisms ◽  
Kinin System ◽  
Kallikrein Kinin System ◽  
Control Study

Objective: Prolylcarboxypeptidase (PRCP) is a negative regulator of the pressor actions of the renin–angiotensin–aldosterone system. It is also involved in the kallikrein–kinin system. This gene has an important role in blood pressure (BP) regulation. Methods: A case–control study was performed for 615 Yi participants (303 cases and 312 controls) from a remote mountainous area in Yunnan Province of China. For the PRCP gene, 11 tag single-nucleotide polymorphisms were genotyped using the polymerase chain reaction-restriction fragment length polymorphism method. Results: The PRCP gene rs12290550 was associated with the occurrence of essential hypertension (EH) and BP traits. Logistic regression analysis indicated that the rs12290550 T allele was significantly linked to the risk of EH (odds ratio (OR) = 1.85, 95% confidence interval (CI) 1.44–2.39, p = 0.2 × 10−5). Under Bonferroni correction, the H7 TAGCACTAACA haplotype containing the risk allele rs12290550 T increased the risk of EH (OR = 4.53, 95% CI 2.29–8.93, p = 0.2×10−5). Conclusions: The findings of this study demonstrate the strong association of the PRCP gene with EH. rs12290550 may be a useful genetic predictor of EH in the Yi minority.

ARG1Gene Polymorphisms and Their Association in Individuals with Essential Hypertension: A Case–Control Study

2018 ◽  
Vol 37 (7) ◽  
pp. 609-616 ◽  
Author(s):  
Syed Fawad Ali Shah ◽  
Tahir Iqbal ◽  
Raheel Qamar ◽  
Muhammad Arshad Rafiq ◽  
Sabir Hussain
Keyword(s):  
Essential Hypertension ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

Common variation in KLKB1 and essential hypertension risk: tagging-SNP haplotype analysis in a case-control study

2007 ◽  
Vol 121 (3-4) ◽  
pp. 327-335 ◽  
Author(s):  
Xiangfeng Lu ◽  
Weiyan Zhao ◽  
Jianfeng Huang ◽  
Hongfan Li ◽  
Wei Yang ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Haplotype Analysis ◽  
Case Control Study ◽  
Case Control ◽  
Tagging Snp ◽  
Common Variation ◽  
Hypertension Risk ◽  
Control Study

scholarly journals Association between Human Urotensin II and Essential Hypertension—A 1:1 Matched Case-Control Study

PLoS ONE ◽  
2013 ◽  
Vol 8 (12) ◽  
pp. e81764 ◽  
Author(s):  
Hao Peng ◽  
Mingzhi Zhang ◽  
Xiaoqin Cai ◽  
Jennifer Olofindayo ◽  
Anna Tan ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Case Control Study ◽  
Case Control ◽  
Urotensin Ii ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study
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