Tendon Healing in Vivo and in Vitro: Neutralizing Antibody to TGF-β Improves Range of Motion After Flexor Tendon Repair

Author(s):  
Changsuo Xia ◽  
Xuanying Yang ◽  
Ying-Zhen Wang ◽  
Kang Sun ◽  
Lina Ji ◽  
...  
2006 ◽  
Vol 31 (5) ◽  
pp. 524-529 ◽  
Author(s):  
B. W. SU ◽  
F. J. RAIA ◽  
H. M. QUITKIN ◽  
M. PARISIEN ◽  
R. J. STRAUCH ◽  
...  

The purpose of this study was to examine the in vivo characteristics of the stainless-steel Teno Fix™ device used for flexor tendon repair. The common flexor digitorum superficialis tendon was transected in 16 dogs and repaired with the device. The animals were euthanized at 3, 6, or 12 weeks postoperatively. Difficulties with cast immobilization led nine of 16 animals to be full weight bearing too early, leading to rupture of their repairs. The seven tendons with successful primary repairs (gap <2 mm) underwent histological examination. This in vivo study demonstrates that use of the Teno Fix™ in “suture” of dog flexor tendons did not lead to scarring at the tendon surface, does not cause an inflammatory reaction within the tendon and does not interfere with tendon healing.


2000 ◽  
Vol 82 (3) ◽  
pp. 68
Author(s):  
Matthew J. Silva ◽  
Michael D. Brodt ◽  
Martin I. Boyer ◽  
Timothy S. Morris ◽  
Haralambos Dinopoulos ◽  
...  

2000 ◽  
Vol 82 (8) ◽  
pp. 56
Author(s):  
Matthew J. Silva ◽  
Michael D. Brodt ◽  
Martin I. Boyer ◽  
Timothy S. Morris ◽  
Haralambos Dinopoulos ◽  
...  

2000 ◽  
Vol 82 (12) ◽  
pp. 77
Author(s):  
Matthew J. Silva ◽  
Michael D. Brodt ◽  
Martin I. Boyer ◽  
Timothy S. Morris ◽  
Haralambos Dinopoulos ◽  
...  

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Ayman Gamal ◽  
Amr Magdy ◽  
Neven Mahmoud ◽  
Ahmad F El Sherif ◽  
Ahmed M Gad

Abstract Background Flexor tendon injuries are a commonly occurring injury presenting to hand surgeons. Using PRP to augment tendon healing has been advocated only recently. Few studies discussed the effect of injection of PRP in tendon healing after tendon repair in large joints as regard functional outcome and range of motion (e.g. Achilles tendon and rotator cuff) Objective To study the effect of combination of PRP injection with physiotherapy on gliding and range of motion improvement after zone II flexor tendon repair. Patients and Methods prospective interventional controlled clinical study preformed on 40 patients with zone II flexor tendon injury. Patients were divided into two groups, group I (interventional group) PRP was injected around the tendon at the site of repair after one and six weeks of repair and patients received physiotherapy according to our unit protocol. In group II (control group) patients received physiotherapy only. Both groups were evaluated at six and twelve weeks regarding the range of motion according to Buck-Gramko II criteria. Results Based on the Buck-Gramcko II criteria, the overall results ranged between fair and good in both groups after six weeks of repair, the score ranged between 7-16 (mean= 11.5) in group I and 6-14 (mean= 10) in group II, There was no statistical difference between the two groups (P = 0.46).After 12 weeks of repair, the overall results ranged between good and excellent in both groups, the score ranged between 11-17 (mean= 14) in group I and 9-16 (mean=12.5) in group II. There was no statistical difference between the two groups (p = 0.207). Conclusion PRP injection had no statistical significant effect of on the gliding after flexor tendon repair at zone II.


2001 ◽  
Vol 26 (5) ◽  
pp. 833-840 ◽  
Author(s):  
David W. Sanders ◽  
Andrew D. Milne ◽  
James A. Johnson ◽  
Cynthia E. Dunning ◽  
Robert S. Richards ◽  
...  

2019 ◽  
Vol 2 (1) ◽  
pp. 29
Author(s):  
FeifyA B. Mahmoud ◽  
WadidaH Abd El-Kader El-Sayed ◽  
AmirA.E Saidi Ahmed ◽  
AmirN W. Mawad ◽  
OsamaF A. Al Balah ◽  
...  

1998 ◽  
Vol 23 (1) ◽  
pp. 37-40 ◽  
Author(s):  
L. GORDON ◽  
M. TOLAR ◽  
K. T. VENKATESWARA RAO ◽  
R. O. RITCHIE ◽  
S. RABINOWITZ ◽  
...  

We have developed a stainless steel internal tendon anchor that is used to strengthen a tendon repair. This study tested its use in vitro to produce a repair that can withstand the tensile strength demands of early active flexion. Fresh human cadaver flexor digitorum profundus tendons were harvested, divided, and then repaired using four different techniques: Kessler, Becker or Savage stitches, or the internal tendon anchor. The internal splint repairs demonstrated a 99–270% increase in mean maximal linear tensile strength and a 49–240% increase in mean ultimate tensile strength over the other repairs. It is hoped that this newly developed internal anchor will provide a repair that will be strong enough to allow immediate active range of motion.


Author(s):  
David Warwick ◽  
Roderick Dunn ◽  
Erman Melikyan ◽  
Jane Vadher

Anatomy and physiology 392Tendon healing 394Flexor tendon anatomy 396Flexor tendon zones of injury 400Flexor tendon suture techniques 402Flexor tendon repair 404Closed flexor tendon rupture 410Flexor tenolysis 412Flexor tendon reconstruction 414Extensor tendon anatomy 418Extensor tendon repair ...


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