Corneal Ulcer in a Child Caused by Nocardia asteroides Following Corneal Perforation

1995 ◽  
Vol 32 (1) ◽  
pp. 55-56
Author(s):  
Ranit Filling ◽  
Pablo Yagupsky ◽  
Irit Rosenblatt ◽  
Natan Keller ◽  
Tevika Tessler ◽  
...  
2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Naya K ◽  
◽  
Lidya I ◽  
Hasnaoui I ◽  
Tazi H ◽  
...  

Corneal perforation is a potentially devastating complication that can result from numerous conditions that precipitate corneal melting. We report a clinical of a 65 years old woman who has presented in the emergency room with a non traumatic corneal perforation, with expulsion of the lens. Complicated by the presence of a chronic antecedent of corneal ulcer (Figure 1).


1982 ◽  
Vol 94 (1) ◽  
pp. 123-124 ◽  
Author(s):  
Lawrence W. Hirst ◽  
William G. Merz ◽  
W. Richard Green

1999 ◽  
Vol 37 (7) ◽  
pp. 2392-2392
Author(s):  
Uma M. Tendolkar ◽  
Ami Varaiya ◽  
A. S. Ahuja ◽  
S. A. Motwane ◽  
A. S. Gogate

2020 ◽  
Author(s):  
Miki Hata Mizuno ◽  
Yuichi Uchino ◽  
Shigeto Shimmura ◽  
Kazuo Tsubota

Abstract Background To evaluate the long-term results of therapeutic keratoplasty for a consecutive case series of corneal perforation.Methods The cases comprised 41 eyes (41 patients) that underwent therapeutic keratoplasty using cryopreserved donor grafts at the Keio University Hospital between January 2012 and December 2016. The eyes were evaluated regarding the cause of corneal perforation, surgical procedure, size of the perforation, presence of anterior chamber collapse, visual prognosis, and complications.Results The major causative diseases included herpetic keratitis (n = 11), bacterial and fungal corneal ulcer (n = 4), Mooren’s ulcer (n = 5), severe dry eye (n = 4), and neuroparalytic keratitis (n = 4). Penetrating keratoplasty was performed in 28 eyes (68.2%), lamellar keratoplasty in 8 eyes (19.5%), and keratoepithelioplasty in 5 eyes (12.2%).


2021 ◽  
Vol 1 (1) ◽  
pp. 22
Author(s):  
Nabilah Afifah ◽  
Herwindo Dicky Putranto ◽  
Lely Retno Wulandari

Introduction: Pseudomonas aeruginosa (P. aeruginosa) is the leading cause of corneal ulcers in children 0 to 3 years of age compared to children in general. Case presentation: A two-months-old infant presented with whitish patches on the right eye two days before admission. A central corneal ulcer with a size of 7-mm x 7-mm accompanied by corneal thinning and melting was shown on the right cornea. It is was surrounded by greyish white creamy infiltrates. Corneal scraping showed Pseudomonas aeruginosa specimens. The cornea became perforate and crystalline lens extrusion was found at the day after intravenous ceftriaxone, levofloxacin eye drop, and cefazoline fortified eye drop administering. It might be caused by bacterial elastase and toxin which contributed to corneal damage. The patient was underwent a multilayer Amniotic Membrane Transplantation (AMT) combined with a pericardial patch graft due to corneal perforation. Two months post-AMT and pericardial patch graft the corneal perforation became entirely heal due to multilayer AMT, despite lysis of the pericardial patch graft. Corneal scar formation and reduction of vitreous opacity in ultrasound examination were shown. The patient was planned to undergo keratoplasty. Conclusions: Corneal ulcers due to Pseudomonas aeruginosa are highly destructive. The levels of infection, diagnostic, and therapeutic are still problems in pediatric patients. Lens extrusion and lysis of the pericardial patch graft are examples in this case. Keratoplasty is the definitive treatment for corneal ulcers with perforation; however, multilayer AMT combined with pericardial patch graft can be used as an alternative therapy to accelerate wound healing, reduce inflammation, and maintain the integrity of the eyeball.


1987 ◽  
Vol 105 (4) ◽  
pp. 464-464 ◽  
Author(s):  
M. Srinivasan ◽  
S. Sharma

2020 ◽  
Vol 36 (4) ◽  
Author(s):  
Sidrah Riaz ◽  
Muhammad Tariq Khan ◽  
Khalid Mehmood ◽  
Mahfooz Hussain ◽  
Sara Riaz

Purpose:  To study the effect of intrastromal Voriconazole for treatment of resistant fungal keratitis in a tertiary care eye hospital in Lahore, Pakistan. Study Design:  Experimental interventional study. Place and Duration of Study:  Avicenna Medical College Hospital, Lahore, from July 2017 to July 2019. Methods:  Sixty four patients were selected. All patients with fugal keratitis were included. The patients with previous corneal scar, mature cataract, endophthalmitis, Panophthalmitis, scleral involvement, impending or frank corneal perforation and uncontrolled diabetic patientswere excluded.Corneal scrapings of all patients were sent for 10% KOH staining. All patients were given intrastromal Voriconazole at 3 to 4 sites in divided doses in one ml syringe with 27-guage needle. Injection was repeated on 4th and 8th day. It was combined by topical antifungal and antibiotic eye drops six hourly. Patients were followed at day two, five, nine, three weeks and at 3 months. Results:  There were 55 males and 9 females. Average size of ulcer was 6.4mm ranging from 5.5mm ± 1.8mm. Fifty six (88%) patient showed improvement while eight (12%) patients ended up in melting of cornea which was managed with tectonic corneal graft. In three (5%) patients penetrating Keratoplasty was done. Conjunctival congestion and ocular pain improved significantly one week after third dose but final visual acuity was not significantly improved due to scarring. Conclusion:  The intrastromal corneal voriconazole is an effective treatment for fungal keratitis in term of healing corneal ulcer, control of infection and saving of eye from corneal perforation and permanent blindness. Key Words:  Voriconazole, Fungal keratitis, Penetrating Keratoplasty.


2020 ◽  
Vol 61 (12) ◽  
pp. 1527-1531
Author(s):  
Sung Joon Kim ◽  
Sang Cheol Yang ◽  
Yeon Ji Jo ◽  
Jong Soo Lee

1998 ◽  
Vol 36 (4) ◽  
pp. 1154-1156 ◽  
Author(s):  
Uma M. Tendolkar ◽  
Ami Varaiya ◽  
A. S. Ahuja ◽  
S. A. Motwane ◽  
A. S. Gogate

Nocardia asteroides is a rare cause of keratitis usually associated with trauma. We report a case of corneal ulceration caused by N. asteroides in a patient with leprosy. This is the first case report of nocardial keratitis from Southeast Asia. The diminished corneal sensation in a patient with leprosy could be a predisposing factor for development or exacerbation of corneal ulceration.


2020 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
Athi Purnasari ◽  
Ratna Doemilah ◽  
Ismi Zuhria

Corneal perforation may be associated with prolapse of ocular tissue. We present a rare case reportan11 months-old female presented prolapsed of right eye. She was earlier diagnosedwithright corneal ulcer anddescemetocele. Physicalexamination revealed perforatedcornea.On ultrasound examination showedvitreous hazzinessand membranous opacity assumed due to inflammation. Based on examinationswe suspectedmalignancy process and performed enucleation withautogenous Dermis Fat Graft (DFG) which harvested onthigh region.Histopathology examination revealed chronic inflammation process.Hence, determining the causative factors of the prolapsed eye is the key for better management and prognosis.


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