Non-Traumatic Corneal Perforation

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Naya K ◽  
◽  
Lidya I ◽  
Hasnaoui I ◽  
Tazi H ◽  
...  
Keyword(s):  
Emergency Room ◽  
Corneal Ulcer ◽  
Corneal Perforation ◽  
Corneal Melting

Corneal perforation is a potentially devastating complication that can result from numerous conditions that precipitate corneal melting. We report a clinical of a 65 years old woman who has presented in the emergency room with a non traumatic corneal perforation, with expulsion of the lens. Complicated by the presence of a chronic antecedent of corneal ulcer (Figure 1).

scholarly journals UVA/Riboflavin Cross-Linking as an Alternative Treatment for Therapeutic Keratoplasty in Corneal Melting

2012 ◽  
Vol 1 (1) ◽  
pp. 61-65 ◽  
Author(s):  
MJ Tassignon ◽  
C Koppen ◽  
N Al-Sabai
Keyword(s):  
Medical Treatment ◽  
Alternative Treatment ◽  
Case Series ◽  
The Other ◽  
Cross Linking ◽  
Corneal Perforation ◽  
Rapid Improvement ◽  
Corneal Ulcers ◽  
Ulcerative Keratitis ◽  
Corneal Melting

ABSTRACT Purpose To demonstrate the effectiveness of UVA/riboflavin cross-linking (CXL) in the treatment of therapy resistant corneal melting of different etiology. Methods This paper describes a series of four cases presenting severe ulcerative keratitis with infectious and noninfectious causes. In spite of intensive medical treatment, corneal melting did develop in all four eyes. CXL was performed to avoid imminent corneal perforation. Results After CXL, there was a rapid improvement in two eyes which healed completely within a month. In the other two eyes, an emergency keratoplasty had to be performed. Conclusion This case series highlights the effectiveness of CXL in the treatment of corneal melting as an addition to our current therapeutic armamentarium. Improvement can be expected in a few days after treatment. CXL can be considered as an adjunct therapy as soon as melting appears in severe corneal ulcers not responding to conventional, intensive treatment. How to cite this article Al-Sabai N, Koppen C, Tassignon MJ. UVA/Riboflavin Cross-Linking as an Alternative Treatment for Therapeutic Keratoplasty in Corneal Melting. Int J Keratoco Ectatic Corneal Dis 2012;1(1):61-65.

The Failure Risk of Surgical Therapy for Corneal Perforations Using Cryopreserved Donor Corneas

2020 ◽  
Author(s):  
Miki Hata Mizuno ◽  
Yuichi Uchino ◽  
Shigeto Shimmura ◽  
Kazuo Tsubota
Keyword(s):  
Penetrating Keratoplasty ◽  
Corneal Ulcer ◽  
Case Series ◽  
University Hospital ◽  
Long Term Results ◽  
Lamellar Keratoplasty ◽  
Corneal Perforation ◽  
Consecutive Case ◽  
Donor Corneas

Abstract Background To evaluate the long-term results of therapeutic keratoplasty for a consecutive case series of corneal perforation.Methods The cases comprised 41 eyes (41 patients) that underwent therapeutic keratoplasty using cryopreserved donor grafts at the Keio University Hospital between January 2012 and December 2016. The eyes were evaluated regarding the cause of corneal perforation, surgical procedure, size of the perforation, presence of anterior chamber collapse, visual prognosis, and complications.Results The major causative diseases included herpetic keratitis (n = 11), bacterial and fungal corneal ulcer (n = 4), Mooren’s ulcer (n = 5), severe dry eye (n = 4), and neuroparalytic keratitis (n = 4). Penetrating keratoplasty was performed in 28 eyes (68.2%), lamellar keratoplasty in 8 eyes (19.5%), and keratoepithelioplasty in 5 eyes (12.2%).

scholarly journals Bilateral corneal perforation following the use of traditional herbal medicine treated with conjunctival flap

2014 ◽  
Vol 6 (2) ◽  
pp. 237-239
Author(s):  
Varanisese Naviri ◽  
Roger Dethlefs
Keyword(s):  
Herbal Medicine ◽  
Harmful Effect ◽  
Corneal Perforation ◽  
Full Thickness ◽  
Light Perception ◽  
Traditional Herbal Medicine ◽  
Conjunctival Flap ◽  
The Right ◽  
Corneal Melting ◽  
Iris Prolapse

Introduction: The harmful effect of the herbal medicine to the eye has not been well reported in the literature.Objective: To report a case of bilateral corneal perforation following the use of traditional herbal medicine treated with conjunctival flap.Case: A 46-year-old Fijian man initially presented with bilateral conjunctivitis, which was thought to be an allergic response to the use of herbal medicine. Vision at initial presentation was normal and he was treated conservatively. Upon review a week later, his vision had decreased to light perception in both eyes. The examination revealed bilateral corneal perforation with iris prolapse, which was then treated with a full thickness conjunctival flap in both eyes in the same sitting. Upon review at 3 weeks of intervention, his vision had improved to hand motions in the right eye and 6/60 in the left. The anterior chamber was formed on both sides.  Conclusion: This case illustrates that the use of herbal medicine can cause corneal melting and subsequently perforations and this can be treated with a conjunctival flap.DOI: http://dx.doi.org/10.3126/nepjoph.v6i2.11716Nepal J Ophthalmol 2014; 6(12): 237-239 

scholarly journals A Challenging Management of Pseudomonas Perforated Corneal Ulcer with Multilayer Amniotic Membrane Transplantation and Pericardial Patch Graft in Pediatric Patient

2021 ◽  
Vol 1 (1) ◽  
pp. 22
Author(s):  
Nabilah Afifah ◽  
Herwindo Dicky Putranto ◽  
Lely Retno Wulandari
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Amniotic Membrane ◽  
Corneal Ulcer ◽  
Definitive Treatment ◽  
Amniotic Membrane Transplantation ◽  
Pericardial Patch ◽  
Corneal Perforation ◽  
Corneal Ulcers ◽  
Patch Graft ◽  
The Right

Introduction: Pseudomonas aeruginosa (P. aeruginosa) is the leading cause of corneal ulcers in children 0 to 3 years of age compared to children in general. Case presentation: A two-months-old infant presented with whitish patches on the right eye two days before admission. A central corneal ulcer with a size of 7-mm x 7-mm accompanied by corneal thinning and melting was shown on the right cornea. It is was surrounded by greyish white creamy infiltrates. Corneal scraping showed Pseudomonas aeruginosa specimens. The cornea became perforate and crystalline lens extrusion was found at the day after intravenous ceftriaxone, levofloxacin eye drop, and cefazoline fortified eye drop administering. It might be caused by bacterial elastase and toxin which contributed to corneal damage. The patient was underwent a multilayer Amniotic Membrane Transplantation (AMT) combined with a pericardial patch graft due to corneal perforation. Two months post-AMT and pericardial patch graft the corneal perforation became entirely heal due to multilayer AMT, despite lysis of the pericardial patch graft. Corneal scar formation and reduction of vitreous opacity in ultrasound examination were shown. The patient was planned to undergo keratoplasty. Conclusions: Corneal ulcers due to Pseudomonas aeruginosa are highly destructive. The levels of infection, diagnostic, and therapeutic are still problems in pediatric patients. Lens extrusion and lysis of the pericardial patch graft are examples in this case. Keratoplasty is the definitive treatment for corneal ulcers with perforation; however, multilayer AMT combined with pericardial patch graft can be used as an alternative therapy to accelerate wound healing, reduce inflammation, and maintain the integrity of the eyeball.

scholarly journals Corneal Perforation Self-Healing with an Iris Plug in the Cornea

2020 ◽  
Vol 11 (2) ◽  
pp. 330-335
Author(s):  
Liene Muceniece ◽  
Inesa Markevica ◽  
Guna Laganovska
Keyword(s):  
Anterior Part ◽  
Visual Outcome ◽  
Self Healing ◽  
Corneal Perforation ◽  
Fungal Treatment ◽  
Good Visual Outcome ◽  
Corneal Scar ◽  
Positive Effect ◽  
Corneal Melting

Keratitis treatment outcome is usually dependent on the targeted treatment of the cause. We want to present a small corneal ulcer of unidentified origin that progressed into corneal melting and resulted in corneal perforation. The patient had a widespread antibacterial and fungal treatment and an ophthalmological follow-up with slit-lamp examination and AS-OCT. The spontaneous iris plug in the cornea helped to solve the anterior chamber collapse and made permanent anatomical changes in the anterior part. A 45-week follow-up found a hyperdense stromal corneal scar with 556-µm-wide stable iris-cornea contact and BCVA of 0.8. As a result, an iris plug in the cornea after corneal perforation can have a positive effect on healing and lead to good visual outcome.

scholarly journals Voriconazole in Treatment of Resistant Fungal Keratitis

2020 ◽  
Vol 36 (4) ◽  
Author(s):  
Sidrah Riaz ◽  
Muhammad Tariq Khan ◽  
Khalid Mehmood ◽  
Mahfooz Hussain ◽  
Sara Riaz
Keyword(s):  
Penetrating Keratoplasty ◽  
Corneal Ulcer ◽  
Tertiary Care ◽  
Fungal Keratitis ◽  
Eye Drops ◽  
Corneal Perforation ◽  
College Hospital ◽  
Medical College ◽  
Corneal Scar ◽  
Average Size

Purpose:  To study the effect of intrastromal Voriconazole for treatment of resistant fungal keratitis in a tertiary care eye hospital in Lahore, Pakistan. Study Design:  Experimental interventional study. Place and Duration of Study:  Avicenna Medical College Hospital, Lahore, from July 2017 to July 2019. Methods:  Sixty four patients were selected. All patients with fugal keratitis were included. The patients with previous corneal scar, mature cataract, endophthalmitis, Panophthalmitis, scleral involvement, impending or frank corneal perforation and uncontrolled diabetic patientswere excluded.Corneal scrapings of all patients were sent for 10% KOH staining. All patients were given intrastromal Voriconazole at 3 to 4 sites in divided doses in one ml syringe with 27-guage needle. Injection was repeated on 4th and 8th day. It was combined by topical antifungal and antibiotic eye drops six hourly. Patients were followed at day two, five, nine, three weeks and at 3 months. Results:  There were 55 males and 9 females. Average size of ulcer was 6.4mm ranging from 5.5mm ± 1.8mm. Fifty six (88%) patient showed improvement while eight (12%) patients ended up in melting of cornea which was managed with tectonic corneal graft. In three (5%) patients penetrating Keratoplasty was done. Conjunctival congestion and ocular pain improved significantly one week after third dose but final visual acuity was not significantly improved due to scarring. Conclusion:  The intrastromal corneal voriconazole is an effective treatment for fungal keratitis in term of healing corneal ulcer, control of infection and saving of eye from corneal perforation and permanent blindness. Key Words:  Voriconazole, Fungal keratitis, Penetrating Keratoplasty.

scholarly journals Multilayer Collagen Sheet Graft for Corneal Perforation with a Corneal Ulcer

2020 ◽  
Vol 61 (12) ◽  
pp. 1527-1531
Author(s):  
Sung Joon Kim ◽  
Sang Cheol Yang ◽  
Yeon Ji Jo ◽  
Jong Soo Lee
Keyword(s):  
Corneal Ulcer ◽  
Corneal Perforation ◽  
Sheet Graft

Repeated Melting of Corneal Grafts in a Patient with Rheumatoid Arthritis and Sjögren's Syndrome

1992 ◽  
Vol 2 (1) ◽  
pp. 36-38 ◽  
Author(s):  
G. Petroutsos ◽  
A. Drosos ◽  
K. Psilas
Keyword(s):  
Rheumatoid Arthritis ◽  
Sjögren’S Syndrome ◽  
Corneal Ulcer ◽  
Sjögren's Syndrome ◽  
Sjogren’S Syndrome ◽  
Sjogren's Syndrome ◽  
Severe Rheumatoid Arthritis ◽  
Corneal Melting ◽  
Sjögren‘S Syndrome

We present a case of corneal melting in a patient with severe rheumatoid arthritis and Sjögren's syndrome. The melting appeared in the area of a bacterial corneal ulcer that healed after treatment with antibiotics. No signs of scleritis were present. Repeated melting of two corneal grafts was seen after surgery.

scholarly journals CASE REPORT AWARENESS TO PROLAPSE OF THE EYE IN BABY

2020 ◽  
Vol 4 (1) ◽  
pp. 1
Author(s):  
Athi Purnasari ◽  
Ratna Doemilah ◽  
Ismi Zuhria
Keyword(s):  
Case Report ◽  
Chronic Inflammation ◽  
Rare Case ◽  
Corneal Ulcer ◽  
Ultrasound Examination ◽  
Ocular Tissue ◽  
Fat Graft ◽  
Corneal Perforation ◽  
Causative Factors

Corneal perforation may be associated with prolapse of ocular tissue. We present a rare case reportan11 months-old female presented prolapsed of right eye. She was earlier diagnosedwithright corneal ulcer anddescemetocele. Physicalexamination revealed perforatedcornea.On ultrasound examination showedvitreous hazzinessand membranous opacity assumed due to inflammation. Based on examinationswe suspectedmalignancy process and performed enucleation withautogenous Dermis Fat Graft (DFG) which harvested onthigh region.Histopathology examination revealed chronic inflammation process.Hence, determining the causative factors of the prolapsed eye is the key for better management and prognosis.

scholarly journals Case of Corneal Perforation as a Complication after Uneventful CXL without Infection

2013 ◽  
Vol 2 (3) ◽  
pp. 139-142
Author(s):  
Goktug Demirci ◽  
Akif Ozdamar
Keyword(s):  
Standard Treatment ◽  
Cell Damage ◽  
Surface Damage ◽  
Adverse Outcomes ◽  
Corneal Perforation ◽  
Endothelial Cell Damage ◽  
Treatment Procedure ◽  
Corneal Collagen Crosslinking ◽  
Corneal Melting ◽  
Corneal Collagen

ABSTRACT Purpose To demonstrate that UVA/riboflavin crosslinking (CXL) can cause corneal melting in some unpredictable cases. Materials and methods We will present a case report of 25-year-old male patient referred for emergency keratoplasty which is due to corneal melting and perforation developed after uneventful CXL procedure for the treatment of keratoconus. Results We performed uncomplicated penetrating keratoplasty of the left eye in our hospital. Conclusion CXL is gradually becoming the standard treatment procedure for progressive keratoconus and the only major safety concerns associated with CXL are ocular surface damage and endothelial cell damage. This case has shown, however, that even if CXL seems to have been successful, there is still a risk of adverse outcomes. Our report suggests that further research is necessary regarding the safety of corneal collagen crosslinking in corneas with keratoconus. How to cite this article Demirci G, Ozdamar A. Case of Corneal Perforation as a Complication after Uneventful CXL without Infection. J Kerat Ect Cor Dis 2013;2(3):139-142.

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