Gonadal dysfunction in male patients with chronic renal failure undergoing hemodialysis

This study aims to determine the presence or absence of protein in urine in patients with chronic renal failure. From the results of the study it was found that patients with chronic kidney failure in Martha Friska Multatuli General Hospital Medan from the 80 most patients in positive +++. Many patients with chronic kidney failure are male patients (62.5%) compared to female patients (37.5%) and the results of the examination based on age increase with age, ie at the age of 45 years and above. This type of research is descriptive analytic. Data is taken by recording medical record data of patients with chronic kidney failure based on age, sex and year. The study was conducted from January 2015 to December 2016. The place for conducting the research was conducted at Martha Friska Multatuli General Hospital (RSU) Medan. The study sample was urine samples from all patients with chronic renal failure. It can be concluded that the picture of protein in urine in patients with chronic kidney failure increases every year.

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Comorbidity in Adult Patients Hospitalized with Type 2 Diabetes in Northeast China: An Analysis of Hospital Discharge Data from 2002 to 2013

BioMed Research International ◽

10.1155/2016/1671965 ◽

2016 ◽

Vol 2016 ◽

pp. 1-9 ◽

Cited By ~ 2

Author(s):

Hui Chen ◽

Yaoyun Zhang ◽

Di Wu ◽

Chunxiu Gong ◽

Qing Pan ◽

...

Keyword(s):

Type 2 Diabetes ◽

Renal Failure ◽

Essential Hypertension ◽

Chronic Renal Failure ◽

Hospital Discharge ◽

Northeast China ◽

Hospital Discharge Data ◽

Discharge Data ◽

Male Patients

This study aims to evaluate the comorbidity burden and patterns among adult patients hospitalized with a diagnosis of type 2 diabetes mellitus (T2DM) in Northeast China using hospital discharge data derived from the electronic medical record database between 2002 and 2013. 12.8% of 4,400,892 inpatients aged ≥18 had a diagnosis of T2DM. Sex differences in prevalence varied among those aged <50, 50–59, and ≥60. Twenty-seven diseases were determined as major comorbidities of T2DM. Essential hypertension was the most common comorbidity of T2DM (absolute cooccurrence risk, 58.4%), while T2DM was also the most popular comorbidity of essential hypertension. Peripheral and visceral atherosclerosis showed the strongest association (relative cooccurrence risk, RCoR 4.206). For five leading comorbidities among patients aged ≥40, male patients had a stronger association with disorders of lipid metabolism than female patients (RCoR 2.779 versus 2.099), and female patients had a stronger association with chronic renal failure than male patients (RCoR 2.461 versus 2.155). Leading comorbidities, except chronic renal failure, had declining associations with T2DM with increased age. Collectively, hospital discharge data can be used to estimate disease prevalence and identify comorbidities. The findings provided comprehensive information on comorbidity patterns, helping policy makers and programs in public health domains to estimate and evaluate the epidemic of chronic diseases.

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Plasma LRH levels in chronic renal failure before and during haemodialysis

Acta Endocrinologica ◽

10.1530/acta.0.1030145 ◽

1983 ◽

Vol 103 (2) ◽

pp. 145-150 ◽

Cited By ~ 5

Author(s):

Miyao Matsubara ◽

Koji Nakagawa ◽

Katsuya Nonomura ◽

Noriaki Hirota

Keyword(s):

Renal Failure ◽

Chronic Renal Failure ◽

Plasma Proteins ◽

Feedback Inhibition ◽

Displacement Curve ◽

Basal Plasma ◽

Male Patients ◽

High Concentrations ◽

Primary Gonadal Failure ◽

Gonadal Failure

Abstract. Endogenous immunoreactive luteinizing hormone – releasing hormone (LRH) in plasma was determined in 6 male and 7 female patients with chronic renal failure before and during haemodialysis. Basal plasma LRH levels ranged from 5.8 to 23.0 pg/ml and, in 11 out of 13 patients, were above the levels seen in healthy subjects (less than 7 pg/ml for men and less than 8 pg/ml for women). This immunoreactivity was eluted in identical fractions with synthetic LRH and plasma extracts from climacteric women on Sephadex G-25 chromatography, and the dilution gave a displacement curve parallel to the standard. Within 5 h of haemodialysis, these high LRH levels declined into the normal range. The concentraions of LH in plasma in these patients were also elevated, but those of testosterone in male patients were decreased. These results suggest 1) that elevated plasma LRH reflects decreased feedback inhibition by primary gonadal failure and might in turn be responsible at least in part for high concentrations of plasma LH in chronic renal failure, and 2) that plasma LRH is mainly not bound to plasma proteins.

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Recent Advances in Investigation, Prevention, and Management of Healthcare-Associated Infections (HAIs): Resistant Multidrug Strain Colonization and Its Risk Factors in an Intensive Care Unit of a University Hospital

BioMed Research International ◽

10.1155/2019/2510875 ◽

2019 ◽

Vol 2019 ◽

pp. 1-9 ◽

Cited By ~ 6

Author(s):

Dana Carmen Zaha ◽

Rita Kiss ◽

Csaba Hegedűs ◽

Rudolf Gesztelyi ◽

Mariann Bombicz ◽

...

Keyword(s):

Risk Factors ◽

Intensive Care Unit ◽

Renal Failure ◽

Intensive Care ◽

Chronic Renal Failure ◽

Bacterial Colonization ◽

Chronic Liver ◽

Isolation And Identification ◽

Icu Admission ◽

Male Patients

Active screening for resistant multidrug strain carriers remains an important component of infection control policy in any healthcare setting indifferent of financial and logistical costs. The objective of our study was to determine the spectrum of bacterial colonization individually among intensive care unit patients. A retrospective observational study was performed in the Intensive Care Unit of Emergency Clinical County Hospital of Oradea during 2017. Medical records of the patients were used for evaluation of source of ICU admission, previous antibiotic therapy, comorbidities, and length of hospital stay. Nasal and groin swabs for MRSA detection and rectal swabs for ESBL, VRE, and CRE detection were collected upon ICU admission of all patients in the first 24 hours and after 7 days. Swab samples were processed for isolation and identification of these resistant multidrug strains. Bacterial colonization on admission was detected in a quarter of patients included in the study. Carbapenemase-producing bacteria were the most common colonizers (21.16%). On admission, 12.06% of patients have been colonized by ESBL-producing members of the family Enterobacterales. Risk factors for colonization on admission to the ICU were chronic liver diseases and chronic renal failure for ESBL infection and chronic liver disease for CRE in male patients. Evaluation of Carmeli’s score for male patients showed association only with CRE colonization. Chronic renal failure was found as risk factor for ESBL colonization in female patients. The prevalence of MRSA was 5.23% and less than 1% for VRE. There was no association between any risk factors studied and the presence of S. aureus or VRE upon admission. The 7-day ICU stay also proved to be an increased risk for ESBL and CRE infection.

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The excretion of metabolites of testosterone and of estradiol in male patients with chronic renal failure

Steroids ◽

10.1016/0039-128x(75)90070-7 ◽

1975 ◽

Vol 26 (4) ◽

pp. 508-515 ◽

Cited By ~ 8

Author(s):

E. van Kammen ◽

J.H.H. Thijssen ◽

G.H. Donker ◽

F. Schwarz

Keyword(s):

Renal Failure ◽

Chronic Renal Failure ◽

Male Patients

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THE EFFECT OF MAINTENANCE HAEMODIALYSIS AND RENAL TRANSPLANTATION ON THE PLASMA TESTOSTERONE LEVELS OF MALE PATIENTS IN CHRONIC RENAL FAILURE

Acta Endocrinologica ◽

10.1530/acta.0.0800577 ◽

1975 ◽

Vol 80 (3) ◽

pp. 577-582 ◽

Cited By ~ 16

Author(s):

J. Alaghband Zadeh ◽

K. G. Koutsaimanis ◽

A. P. Roberts ◽

R. Curtis ◽

J. R. Daly

Keyword(s):

Renal Failure ◽

Circadian Rhythm ◽

Renal Transplantation ◽

Chronic Renal Failure ◽

Testosterone Level ◽

Plasma Testosterone ◽

Plasma Testosterone Level ◽

Testosterone Levels ◽

Maintenance Haemodialysis ◽

Male Patients

ABSTRACT Plasma testosterone levels were measured at the beginning of a 14 h period of haemodialysis, one hour later, midway through the period and at the end, in 18 male patients in chronic renal failure. The level fell from 8.70 ± 2.63 nmol/l at the start to 8.08 ± 3.33 nmol/l at the midpoint, and rose again to 10.12 ± 3.9 nmol/l at the end of a dialysis. All seven of the patients tested on a non-dialysis day showed similar levels at the same time. At the beginning of a 10 h dialysis period 19 other male patients showed a plasma testosterone level of 10.12 ± 3.99 nmol/l and, at the end, of 8.98 ± 4.54 nmol/l. Over the same period the plasma corticosteroids rose from 301 ± 101 nmol/l to 483 ± 199 nmol/l. Eight male patients who had had successful renal transplantation had plasma testosterone levels of 15.08 ± 7.49 nmol/l. It is concluded that the plasma testosterone is low in chronic renal failure, but the circadian rhythm is preserved. Treatment with maintenance haemodialysis does not itself affect the plasma testosterone level, or alter the circadian rhythm despite the procedure's being a stress. Successful renal transplantation restores the plasma testosterone to normal in most cases.

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Effect of Metformin and Glimepiride Treatment on Some Biochemical Parameters in Diabetic Male Patients with Chronic Renal Failure

Ibn AL- Haitham Journal For Pure and Applied Science ◽

10.30526/32.2.2137 ◽

2019 ◽

Vol 32 (2) ◽

pp. 38

Author(s):

Ali Mohammed Abbed

Keyword(s):

Renal Failure ◽

Chronic Renal Failure ◽

Total Protein ◽

Biochemical Parameters ◽

Serum Glucose ◽

Control Group ◽

Fasting Serum ◽

Serum Total Protein ◽

Fasting Serum Glucose ◽

Male Patients

The present study was included a measurements of fasting serum glucose, total protein, potassium, and calcium levels in the sera of 25 diabetic male patients suffer from chronic renal failure; their ages range were (32-75) and compared them with 25 healthy males as control group. The aim of this study was to study the effects of antidiabetic drugs on some biochemical parameters such as fasting serum glucose, serum total protein, serum potassium and calcium. The current results demonstrated a hyperkalemia in patients and this increasing of potassium is significantly (p = 0.03), but calcium level showed no significant variations ( p>0.05 ), and serum total protein was significantly decreased in patients as compared to the controls( p = 0.0002 ).

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