MRI-GUIDED NAVIGATION AND POSITIONING SOLUTION FOR REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION

2013 ◽  
Vol 25 (01) ◽  
pp. 1350012 ◽  
Author(s):  
Shangping Liu ◽  
Lin Shi ◽  
Defeng Wang ◽  
Ji Chen ◽  
Zhimin Jiang ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Spatial Relationship ◽  
Brain Anatomy ◽  
3D Navigation ◽  
Healthy Human ◽  
Skull Model ◽  
Spatial Registration ◽  
Mri Guided

A MRI-guided navigation solution for repetitive transcranial magnetic stimulation (rTMS)was designed in this study which integrates optical positioning system to perform positioning and tracking of the magnetic stimulation coil in real-time. The system includes the following procedures: segmentation and 3D reconstruction of brain anatomy from T1-weighted (T1W) MRI, coil calibration and localization, spatial registration between the subject's head and the MRI data and 2D/3D navigation. The 2D/3D navigation provides the spatial relationship between actual sites of the coils and the cortical surface quantitively and allows visualization of the location and orientation of the coil over the brain/head. Verified through the experiments using a phantom human skull model and the head MRI data from a healthy human subject, the proposed navigation system was demonstrated to be flexible, safe, accurate and time efficient.

scholarly journals Repetitive transcranial magnetic stimulation increases phase-amplitude coupling

2017 ◽  
Author(s):  
Chie Nakatani ◽  
Caitlin Mullin ◽  
Johan Wagemans ◽  
Cees van Leeuwen
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Neuronal Firing ◽  
Neural Mass Model ◽  
Mass Model ◽  
Healthy Human ◽  
Lateral Occipital Complex ◽  
Sham Condition ◽  
Phase Amplitude

AbstractA prominent feature of brain activity with relevance to cognitive processes is Phase-Amplitude Coupling (PAC) between slow and fast oscillatory signals. A newly developed neural mass model of cross-frequency coupling [1] predicts, counter-intuitively, that PAC shows sustained increases after repetitive Transcranial Magnetic Stimulation (rTMS). This is because rTMS leads to simultaneous neuronal firing in distinct regions, thereby enhancing the connectivity that, according to the model, is needed for PAC to be increased. We tested this prediction in healthy human volunteers. Two seconds of 10Hz rTMS were applied to the intraparietal sulcus, temporal-parietal junction, and lateral occipital complex. PAC in the subsequent electro-encephalogram was analyzed for two band pairs, theta-gamma and alpha-gamma, and compared to a sham condition. For all stimulation loci, PAC was higher in both band pairs after rTMS than in the sham condition. These results were found to be conform the model prediction. The perspective for using rTMS to modulate cross-band coupling is discussed.

The effects of repetitive transcranial magnetic stimulation on cortical inhibition in healthy human subjects

2006 ◽  
Vol 174 (3) ◽  
pp. 403-412 ◽  
Author(s):  
Zafiris J. Daskalakis ◽  
Bertram Möller ◽  
Bruce K. Christensen ◽  
Paul B. Fitzgerald ◽  
Carolyn Gunraj ◽  
...  
Keyword(s):  
Transcranial Magnetic Stimulation ◽  
Magnetic Stimulation ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Human Subjects ◽  
Cortical Inhibition ◽  
Healthy Human ◽  
Healthy Human Subjects
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