Alginate-Coated Thiolated Chitosan Microspheres for an Oral Drug Delivery System In Vitro

2007 ◽  
pp. 433-436
Author(s):  
Hu Lin Jiang ◽  
Rohidas B. Arote ◽  
Ji Shan Quan ◽  
Mi Kyong Yoo ◽  
You Kyoung Kim ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
Thiolated Chitosan ◽  
Chitosan Microspheres ◽  
Oral Drug Delivery System

In vivo evaluation of an oral drug delivery system for peptides based on S-protected thiolated chitosan

2012 ◽  
Vol 160 (3) ◽  
pp. 477-485 ◽  
Author(s):  
Sarah Dünnhaupt ◽  
Jan Barthelmes ◽  
Javed Iqbal ◽  
Glen Perera ◽  
Clemens C. Thurner ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oral Drug Delivery ◽  
Oral Drug ◽  
In Vivo Evaluation ◽  
Thiolated Chitosan ◽  
Oral Drug Delivery System

scholarly journals Preparation and Evaluation of a Novel Oral Microemulsion Drug Delivery System for Enhancing the Bioavailability of Diltiazem

2021 ◽  
Vol 70 (2) ◽  
Author(s):  
Ranajit Nath ◽  
Ratul Bhowmik ◽  
Rajarshi Chakraborty ◽  
Sourav Datta ◽  
Apala Chakraborty
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Oral Drug Delivery ◽  
In Vitro Release ◽  
Immediate Release ◽  
Oral Drug ◽  
Accelerated Stability ◽  
Oral Drug Delivery System

Diltiazem, a calcium ion cellular influx inhibitor is known for its limited and variable bioavailability. This study is intended to explore the benefits of microemulsion formulation as an oral drug delivery system for immediate release to improve the bioavailability and efficacy of Diltiazem. Methods: Oil in water microemulsion was prepared using the simple water titration method. The optimized formulation was evaluated for physicochemical parameters like viscosity, pH, conductivity, and accelerated stability studies. In vitro release, diltiazem microemulsion was investigated.

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