The Computer-Assisted Design Method of Staggered-Tooth Milling Cutter for Manufacturing of the Complex Helical Surfaces

2014 ◽  
Vol 1036 ◽  
pp. 388-393
Author(s):  
Gheorghe Pleşu

The complex helical surfaces specific for the rotors of the helical compressors and of the screw pumps imply the production of a series of tools providing a high productivity. The staggered-tooth milling cutter achieve these conditions but their design gives rise to difficult problems. In order to optimize their parameters and to facilitate their design, a package of programs has been created to select the constructive parameters of the tool, to calculate the profiles of the plates, the angles of the surface of section, the dimensions of the elements of attachment. In order to include all these elements in an efficient system of design, a series of regular calculations were applied for various parameters that were then included through the CAD software for design and documentation AutoCAD; at the same time, several applications of verification, construction and simulation of the functioning of the tool and of the cutting process were designed. The method applied in this case reduced to a considerable extent the time of design and it also improved the constructive solutions of the staggered-tooth milling cutter.

2013 ◽  
Vol 804 ◽  
pp. 167-173
Author(s):  
Huan Wen Ding ◽  
Guang Wen Yu ◽  
Qiang Tu ◽  
Jian Jian Shen ◽  
Ying Jun Wang

To establish a new three-dimensional (3D) digital design method for osteotomy and assess its application value in the surgical treatment of hemivertebrae. Preoperative 3D digital designs for osteotomy of the hemivertebrae were performed, which included computer simulation of the osteotomy and the internal fixation process, and computer-assisted design (CAD) of the templates for osteotomy of the hemivertebrae, pedicle screw positioning, and internal fixation rods. Template-guided osteotomy of the hemivertebrae plus pedicle screw and rod internal fixation were accurately implemented. The preoperative use of this new computer-aided 3D digitized and paperless surgical design can improve the safety, accuracy, and operative time for osteotomy in the treatment of hemivertebrae.


2013 ◽  
Vol 380-384 ◽  
pp. 1760-1764
Author(s):  
Huan Wen Ding ◽  
Guang Wen Yu ◽  
Qiang Tu ◽  
Jian Jian Shen ◽  
Ying Jun Wang

To establish a new three-dimensional (3D) digital design method for osteotomy and assess its application value in the surgical treatment of hemivertebrae. Preoperative 3D digital designs for osteotomy of the hemivertebrae were performed, which included computer simulation of the osteotomy and the internal fixation process, and computer-assisted design (CAD) of the templates for osteotomy of the hemivertebrae, pedicle screw positioning, and internal fixation rods. Template-guided osteotomy of the hemivertebrae plus pedicle screw and rod internal fixation were accurately implemented. The preoperative use of this new computer-aided 3D digitized and paperless surgical design can improve the safety, accuracy, and operative time for osteotomy in the treatment of hemivertebrae.


2020 ◽  
Vol 27 (1) ◽  
pp. 32-41 ◽  
Author(s):  
Subhash C. Basak ◽  
Apurba K. Bhattacharjee

Background: In view of many current mosquito-borne diseases there is a need for the design of novel repellents. Objective: The objective of this article is to review the results of the researches carried out by the authors in the computer-assisted design of novel mosquito repellents. Methods: Two methods in the computational design of repellents have been discussed: a) Quantitative Structure Activity Relationship (QSAR) studies from a set of repellents structurally related to DEET using computed mathematical descriptors, and b) Pharmacophore based modeling for design and discovery of novel repellent compounds including virtual screening of compound databases and synthesis of novel analogues. Results: Effective QSARs could be developed using mathematical structural descriptors. The pharmacophore based method is an effective tool for the discovery of new repellent molecules. Conclusion: Results reviewed in this article show that both QSAR and pharmacophore based methods can be used to design novel repellent molecules.


Author(s):  
C.H.A.U.V.E.L.-P.I.C.A.R.D. Julie ◽  
B.E.U.R.I.A.T. Pierre-Aurélien ◽  
D.A.U.R.A.D.E. Mathieu ◽  
S.Z.A.T.H.M.A.R.I. Alexandru ◽  
M.O.T.T.O.L.E.S.E. Carmine ◽  
...  

2013 ◽  
Vol 40 (12) ◽  
pp. 959-965 ◽  
Author(s):  
Estella G. da Mota ◽  
Daniel G. Silva ◽  
Maria C. Guimarães ◽  
Elaine F.F. da Cunha ◽  
Matheus P. Freitas

2011 ◽  
Vol 18 (1) ◽  
pp. 103-114 ◽  
Author(s):  
Hatem Hejaz ◽  
Rafik Karaman ◽  
Mustafa Khamis

Vaccine ◽  
2005 ◽  
Vol 23 (17-18) ◽  
pp. 2136-2148 ◽  
Author(s):  
A DEGROOT ◽  
L MARCON ◽  
E BISHOP ◽  
D RIVERA ◽  
M KUTZLER ◽  
...  

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