Investigation of Ag Oxidation and Ion Adsorption on Small Intestinal Submucosa in Simulated Body Fluid through Simultaneous Electrochemical and SPR Measurements

2015 ◽  
Vol 1119 ◽  
pp. 438-443
Author(s):  
Claudiu Constantin Manole ◽  
Ioana Demetrescu
Keyword(s):  
Simulated Body Fluid ◽  
Body Fluid ◽  
Electrochemical Techniques ◽  
Antibacterial Properties ◽  
Small Intestinal Submucosa ◽  
Human Blood Plasma ◽  
Ion Adsorption ◽  
Electrochemical Approach ◽  
Small Intestinal ◽  
Intestinal Submucosa

Small Intestinal Submucosa (SIS) is a material used from ancient times in foods, and more recently as a biomaterial. To ensure antibacterial properties, the presence of ionic Ag+is benefic and brings a minimum of toxicity to the SIS. In this paper, the electrochemical oxidation of Ag is considered to obtain the ionic Ag+. The simultaneous use of Surface Plasmon Resonance (SPR) and Electrochemical techniques opens an insight on Ag oxidation. The study is undertaken in a Simulated Body Fluid (SBF) with ions concentration that closely resembles the concentrations of the human blood plasma for a simulation of the Ag+ions behavior in physiological conditions. The simultaneous SPR and Electrochemical approach highlighted aspects of the ion adsorption into the SIS membrane.

44: Laparoscopic Augmentation Cystoplasty: A Comparison between Native Ileum Versus Small Intestinal Submucosa in the Porcine Model

2004 ◽  
Vol 171 (4S) ◽  
pp. 12-12
Author(s):  
David A. Anderson ◽  
David S. Wang ◽  
Peter C. Fretz ◽  
Thai T. Nguyen ◽  
Howard N. Winfield
Keyword(s):  
Porcine Model ◽  
Small Intestinal Submucosa ◽  
Augmentation Cystoplasty ◽  
Small Intestinal ◽  
Intestinal Submucosa

Immunomodulatory response of layered small intestinal submucosa in a rat bladder regeneration model

2018 ◽  
Vol 107 (6) ◽  
pp. 1960-1969 ◽  
Author(s):  
Ding Xia ◽  
Qing Yang ◽  
Kar‐Ming Fung ◽  
Rheal A. Towner ◽  
Nataliya Smith ◽  
...  
Keyword(s):  
Small Intestinal Submucosa ◽  
Rat Bladder ◽  
Bladder Regeneration ◽  
Small Intestinal ◽  
Intestinal Submucosa

Small intestinal submucosa xenograft to manage lower urinary tract prostheses perforation: a new path?

2021 ◽  
Author(s):  
Florence Cour ◽  
Pierre Munier ◽  
Kevin Kaulanjan ◽  
Adrien Vidart ◽  
Pierre-Olivier Bosset ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Small Intestinal Submucosa ◽  
Small Intestinal ◽  
Intestinal Submucosa ◽  
Lower Urinary

scholarly journals The use of small intestinal submucosa graft for hypospadias repair: Pilot study

2013 ◽  
Vol 11 (4) ◽  
pp. 415-420 ◽  
Author(s):  
Hazem Orabi ◽  
Ahmed S. Safwat ◽  
Ahmed Shahat ◽  
Hisham M. Hammouda
Keyword(s):  
Pilot Study ◽  
Small Intestinal Submucosa ◽  
Hypospadias Repair ◽  
Small Intestinal ◽  
Intestinal Submucosa

Safety and efficacy of the porcine small intestinal submucosa dural substitute: results of a prospective multicenter study and literature review

2007 ◽  
Vol 106 (6) ◽  
pp. 1028-1033 ◽  
Author(s):  
Ghassan K. Bejjani ◽  
Joseph Zabramski ◽  
_ _
Keyword(s):  
Wound Infection ◽  
Small Intestinal Submucosa ◽  
Csf Leak ◽  
Dural Repair ◽  
Dural Substitute ◽  
Csf Leakage ◽  
Porcine Small Intestinal Submucosa ◽  
Small Intestinal ◽  
Intestinal Submucosa

Object Dural substitutes are often needed after neurosurgical procedures to expand or replace dura mater resected during surgery. A new dural repair material derived from porcine small intestinal submucosa (SIS) was evaluated in a prospective multicenter clinical study. Methods Between 2000 and 2003, 59 patients at five different institutions underwent dural reconstruction with the SIS dural substitute, with a minimum follow up of 6 months. The primary goals of the study were to assess the efficacy and safety of the SIS dural substitute according to the rate of cerebrospinal fluid (CSF) leakage, infection, and meningitis. Chiari malformation Type I decompression (32 patients) and tumor resection (18 patients) were the most common procedures performed, with 81% of SIS grafts implanted in the posterior fossa or spine. There was one case of a CSF leak (1.7%), two cases of wound infection (3.4%), and no cases of bacterial meningitis (0%) in the 58 patients available for follow up. In both cases of wound infection, the SIS graft acted as a barrier to infection and was not removed. Intraoperatively, a watertight seal was achieved in all 59 cases. On follow-up imaging available in 27 patients there was no evidence of any adverse reaction to the graft or of cerebral inflammation. Conclusions The SIS dural substitute demonstrated substantial efficacy in these patients after a mean follow up of 7.3 ± 2.2 months. Rates of infection, CSF leakage, and meningitis were comparable to those reported for other dural substitute materials. A lack of adverse reactions to the graft, favorable safety profile, and clinical efficacy all point to the utility of this material as an alternative for dural repair.

Biocompatibility of Small-Intestinal Submucosa in Urinary Tract as Augmentation Cystoplasty Graft and Injectable Suspension

1994 ◽  
Vol 8 (2) ◽  
pp. 125-130 ◽  
Author(s):  
PETER M. KNAPP ◽  
JAMES E. LINGEMAN ◽  
YORAM I. SIEGEL ◽  
STEPHEN F. BADYLAK ◽  
ROBERT J. DEMETER
Keyword(s):  
Urinary Tract ◽  
Small Intestinal Submucosa ◽  
Augmentation Cystoplasty ◽  
Small Intestinal ◽  
Intestinal Submucosa
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