Study of Affinity Interaction of Paeonol and BSA by Vacancy Affinity Capillary Electrophoresis

2013 ◽  
Vol 781-784 ◽  
pp. 1209-1214
Author(s):  
Hai Xing Liu ◽  
Xin Yan Mi ◽  
Jun Wu ◽  
Ai Min Yu ◽  
Li Fei Bai

In this paper, paeonol was studied systemtically. At first, the affinity interaction of paeonol with bovine serum albumin (BSA) was investigated through capillary electrophoresis approach. The association constant of paeonol and BSA was obtained by the vacancy affinity capillary electrophoresis method (VACE). The second, the contents of paeonol were determinede in liuweidihuang pill. In this paper, the new studied method and basic data were offered for further investigating the pharmacology and drug efficacy of paeonol. Meanwhile, the method described would be particularly useful in the quality control of traditional Chinese medicines-liuweidihuang pill.

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