Fabrication and Characterization of Hydroxyapatite/Poly (L-Lactic Acid-Polycaprolactone Nanofibrous Composite Scaffolds

2013 ◽  
Vol 791-793 ◽  
pp. 137-140
Author(s):  
Gui Fang Wu ◽  
Jia Liu ◽  
Yi Wen Ma ◽  
Jian Jin Jiao ◽  
Xiu Feng Xiao
Keyword(s):  
Biological Activity ◽  
Lactic Acid ◽  
Ternary System ◽  
Composite Scaffold ◽  
Composite Scaffolds ◽  
Nanofiber Composite ◽  
Biologic Activity ◽  
Fabrication And Characterization

The multistage aperture nanofibrous composite scaffolds were fabricated by frozen extraction combined with particle leaching from a PLLA/PCL/HA/dioxane/ ethanol ternary system. and then the morphology and biological activity of composite scaffolds were analyzed. Results show that adding the porogen is advantageous to the formation of multistage aperture nanofiber composite scaffolds. And HA adds more conducive to the deposit of CHA on composite scaffolds, raises the biologic activity of the composite scaffold.

Fabrication and Characterization of Polyoxometalate based Nano-hybrids: Evaluation of their role in Biological Activity

2019 ◽  
Vol 35 (4) ◽  
pp. 475-484
Author(s):  
SHIVA ARUN ◽  
◽  
PRABHA BHARTIYA ◽  
AMREEN NAZ ◽  
SUDHEER RAI ◽  
...  
Keyword(s):  
Biological Activity ◽  
Fabrication And Characterization

scholarly journals Fabrication and Characterization of Ta–GelMA–BG Scaffolds by Chemical Crosslinking Processing for Promotion Osteointegration

2021 ◽  
Vol 8 ◽  
Author(s):  
Fujian Zhao ◽  
Xiongfa Ji ◽  
Yang Yan ◽  
Zhen Yang ◽  
Xiaofeng Chen ◽  
...  
Keyword(s):  
Early Stage ◽  
Bone Defects ◽  
Chemical Crosslinking ◽  
Composite Scaffolds ◽  
Load Bearing ◽  
3D Printed ◽  
Fabrication And Characterization ◽  
Cell Adhesion And Proliferation

The repair of bone defects in load-bearing positions still faces great challenges. Tantalum (Ta) has attempted to repair bone defects based on the excellent mechanical properties. However, the osseointegration of Ta needs to be improved due to the lack of osteoinduction. Herein, tantalum–gelatin–methacryloyl–bioactive glass (Ta–GelMA–BG) scaffolds were successfully fabricated by loading BG in 3D-printed Ta scaffolds through a chemical crosslinking method. The results showed that the composite scaffolds have the ability to promote cell adhesion and proliferation. The incorporation of BG resulted in a significant increase in apatite-forming and osteogenesis differentiation abilities. In vivo results indicated that the Ta–GelMA–BG scaffolds significantly enhanced the osteointegration at the early stage after implantation. Overall, the Ta–GelMA–BG scaffolds are a promising platform for the load bearing bone regeneration field.

scholarly journals Fabrication and characterization of poly(l-lactic acid) gels induced by fibrous complex crystallization with solvents

Polymer ◽  
2014 ◽  
Vol 55 (16) ◽  
pp. 4369-4378 ◽  
Author(s):  
Yasuhiro Matsuda ◽  
Akinobu Fukatsu ◽  
Yangyang Wang ◽  
Kazuaki Miyamoto ◽  
Jimmy W. Mays ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Fabrication And Characterization
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