Fabrication and characterization of nano composite scaffold of poly(l-lactic acid)/hydroxyapatite

The multistage aperture nanofibrous composite scaffolds were fabricated by frozen extraction combined with particle leaching from a PLLA/PCL/HA/dioxane/ ethanol ternary system. and then the morphology and biological activity of composite scaffolds were analyzed. Results show that adding the porogen is advantageous to the formation of multistage aperture nanofiber composite scaffolds. And HA adds more conducive to the deposit of CHA on composite scaffolds, raises the biologic activity of the composite scaffold.

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Fabrication and characterization of nano-composite scaffold of PLLA/silane modified hydroxyapatite

Medical Engineering & Physics ◽

10.1016/j.medengphy.2010.02.002 ◽

2010 ◽

Vol 32 (4) ◽

pp. 391-397 ◽

Cited By ~ 48

Author(s):

Xuejun Wang ◽

Guojun Song ◽

Tao Lou

Keyword(s):

Composite Scaffold ◽

Nano Composite ◽

Fabrication And Characterization

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Fabrication and Characterization of Genistein Encapsulated Poly (D, L) Lactic acid Nanoparticles for Pharmaceutical Application

Current Nanoscience ◽

10.2174/1573413711309020021 ◽

2013 ◽

Vol 9 (2) ◽

pp. 293-302 ◽

Cited By ~ 2

Author(s):

Ravikumara N.R ◽

Waree Tiyaboonchai ◽

Basavaraj Madhusudhan

Keyword(s):

Lactic Acid ◽

Pharmaceutical Application ◽

Fabrication And Characterization

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Characterization of Antimicrobial Poly (Lactic Acid)/Nano-Composite Films with Silver and Zinc Oxide Nanoparticles

Materials ◽

10.3390/ma10060659 ◽

2017 ◽

Vol 10 (6) ◽

pp. 659 ◽

Cited By ~ 43

Author(s):

Zhuangzhuang Chu ◽

Tianrui Zhao ◽

Lin Li ◽

Jian Fan ◽

Yuyue Qin

Keyword(s):

Zinc Oxide ◽

Lactic Acid ◽

Zinc Oxide Nanoparticles ◽

Composite Films ◽

Poly Lactic Acid ◽

Oxide Nanoparticles ◽

Nano Composite

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Preparation of Nano-Fibrous Poly(L-lactic acid) Scaffold with Hierarchical Pores

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.418-420.303 ◽

2011 ◽

Vol 418-420 ◽

pp. 303-306

Author(s):

Xue Jun Wang ◽

Tao Lou ◽

Guo Jun Song

Keyword(s):

Tissue Engineering ◽

Lactic Acid ◽

Pore Size ◽

Composite Scaffold ◽

Compressive Modulus ◽

High Porosity ◽

Nano Composite ◽

Hierarchical Pores ◽

Fiber Size ◽

Hierarchical Pore

In this study, a nano-fibrous PLLA scaffold with hierarchical pore was sucessfully fabricated using combined TIPS and particle leaching method.The scaffold had a nano-fibrous PLLA matrix (fiber size 100-800 nm), an interconnective hierarchical pores (1.0- 425 μm), high porosity (>96%). The compressive modulus of scaffold with different pore size was between 0.16 MPa to 0.2 Mpa and it decreased with the increased salt size embedded in. The new nano composite scaffold is potentially a very promising scaffold for tissue engineering.

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