Spectrophotometric Method for the Assay of Chlorhexiidine Acetate

High Sensitivity ◽

Standard Addition ◽

Addition Method ◽

Ultraviolet Spectrophotometry ◽

Good Linear ◽

Sensitivity And Selectivity

To establish the determination of the content of chlorhexiidine acetate by ultraviolet spectrophotometry .The spectra (range: λ=200~320 nm) were processed. The linear ranges of chlorhexidine acetate was at 2~ 20 μg mL-1 .the chlorhexiidine acetate showed good linear correlation.The ultraviolet spectrophotometry data of the samples were also used to evaluate the samples quantitative composition.It was shown that recovery of the method by standard addition method was respectively valued 99.55% for chlorhexiidine acetate .The method was simple,reliable,accurate,reproducible with high sensitivity and selectivity.

Spectrophotometric Method for the Assay of Aspirin

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.602-605.2097 ◽

2014 ◽

Vol 602-605 ◽

pp. 2097-2100

Author(s):

Yan Hong Lei

Keyword(s):

High Sensitivity ◽

Standard Addition ◽

Addition Method ◽

Ultraviolet Spectrophotometry ◽

Selective Method ◽

Good Linear ◽

Sensitivity And Selectivity

A selective method was developed for the determination of aspirin by Spectrophotometric method .The spectra (range: λ=200~320 nm) were processed. The linear ranges of aspirin was at 50.28 ~ 125.7μg • mL-1 .the aspirin showed good linear correlation.The ultraviolet spectrophotometry data of the samples were also used to evaluate the samples’ quantitative composition.It was shown that recovery of the method by standard addition method was respectively valued 102.06% for aspirin .The method was simple,reliable,accurate,reproducible with high sensitivity and selectivity.

Spectrophotometric Method for the Assay of Norfloxacin Lactate

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.989-994.993 ◽

2014 ◽

Vol 989-994 ◽

pp. 993-996

Author(s):

Yan Hong Lei

Keyword(s):

High Sensitivity ◽

Standard Addition ◽

Addition Method ◽

Selective Method

A selective method was developed for the determination of norfloxacin lactate by Spectrophotometric method. The method was simple with high sensitivity and selectivity.It was shown that recovery of the method by standard addition method was respectively valued 102.05% for norfloxacin lactate

Spectrophotometric Method in the Determination of Aminophylline Content

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.602-605.2395 ◽

2014 ◽

Vol 602-605 ◽

pp. 2395-2398

Author(s):

Yan Hong Lei

Keyword(s):

High Sensitivity ◽

Standard Addition ◽

Addition Method ◽

Selective Method

A selective method was developed for the determination of aminophylline by Spectrophotometric method. The method was simple with high sensitivity and selectivity.It was shown that recovery of the method by standard addition method was respectively valued 99.21% for aminophylline.

Simultaneous spectrophotometric determination of phenolic antioxidant (BHA and BHT) concentrations in pharmaceutical preparations and chewing gums using the H-point standard addition method

Macedonian Journal of Chemistry and Chemical Engineering ◽

10.20450/mjcce.2017.1330 ◽

2017 ◽

Vol 36 (2) ◽

pp. 211

Author(s):

Mahmure Özgür ◽

Zeynep Kalaycioğlu ◽

Öznur Dülger

Keyword(s):

Limit Of Detection ◽

Pharmaceutical Preparations ◽

Standard Addition ◽

Butylated Hydroxytoluene ◽

Addition Method ◽

Chewing Gums ◽

Relative Standard

A simple, rapid, and sensitive spectrophotometric method was developed for the simultaneous determination of butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) concentration in pharmaceutical preparations and chewing gums, without prior separation steps, using the H-point standard addition method (HPSAM).The concentration of one antioxidant was calculated by overlapping spectra at two appropriately selected wavelengths at which the interferent, other antioxidant, should has the same absorbance value. Absorbances at two pairs of wavelengths, 265 and 288 nm (with BHA as analyte) or 288 and 293 nm (with BHT as analyte) were monitored, while adding standard solutions of BHA or BHT, respectively. Calibration graphs were determined at 4–20 μgml–1(r = 0.9981) for BHA and 20–100 μgml–1(r = 0.9940) for BHT in binary mixtures. The proposed method was tested and validated using various parameters according to ICH guidelines. The limit of detection (LOD) and limit of quantification (LOQ) were found to be 0.48 and 1.51 μgml–1for BHA and 0.72 and 2.41 μgml–1for BHT, respectively. The percentage recovery ranges were 100.44–102.50 % for BHA and 96.45–100.04 % for BHT, with relative standard deviations (RSD) less than 1.48 % indicating reasonable repeatability of the method. The intra-day and inter-day precision tests showed reliable RSD values (< 2 %). The results obtained using HPSAM were statistically compared with results obtained using the derivative spectrophotometric method that was previously reported by us, showing high similarity between results.

Determination of Vitamin and Aminophylline by a Method of PLS

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.881-883.493 ◽

2014 ◽

Vol 881-883 ◽

pp. 493-496

Author(s):

Yan Hong Lei

Keyword(s):

Vitamin C ◽

Least Squares ◽

Simultaneous Determination ◽

Partial Least Squares ◽

Standard Addition ◽

Addition Method ◽

Pls Method

This paper described a spectrophotometric method for simultaneous determination of two drugs,Vitamin C, aminophylline with the aid of partial least squares. The proposed method was successfully applied to overcome the overlapping of their absorption curves in the UV spectral region.The result was shown that the predictive errors obtained by the PLS method was 9.25%. Recovery of the method by standard addition method was respectively valued 92.43% (for vitamin C) and 102.53% (for aminophylline).