Characterization of TAPE-Gelatin as a Potential Bioadhesive

Bioadhesives have much potential in the medical field as an alternative to sutures in internal surgery. They are easier to use and have better long-term results. Improvement of a new class of adhesives, tannic acid-polyethylene glycol (TAPE), was done by mixing it with gelatin, since it was found that TAPE alone could not be applied to certain internal applications like in inguinal hernia. It failed to close a fresh inguinal hernia sac. Characterization tests were done on the new material, TAPE-gelatin, which proved to have a tissue adhesion strength of 0.41 MPa which is 5 times greater than fibrin glue, good blood biocompatibility with blood clotting index of 97.46%, burst pressure strength that can withstand 1000 mL that is 10 times more than the volume in the peritoneal cavity, and cheaper, with a production cost of Php28.50, than commercially available bioadhesives, which can reach up to Php2,000 – Php30,000 per application. With its desirable properties, cheaper production cost, and large potential for scalability, TAPE-gelatin as a new candidate for medical adhesive was established.

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Characterization of morphology and function of the ‘neo-atria’ after a modified Mustard operation

Global Cardiology Science and Practice ◽

10.21542/gcsp.2021.21 ◽

2021 ◽

Vol 2021 (3) ◽

Author(s):

Mohamed Nagy ◽

Hatem Hosny ◽

Amr El Sawy ◽

Ahmed Mahgoub ◽

Magdi H Yacoub

Keyword(s):

Contractile Function ◽

Postoperative Recovery ◽

Long Term Results ◽

3D Segmentation ◽

Mustard Operation ◽

The Right ◽

And Function ◽

Atrial Systole

Background: There is a pressing need to improve early and long-term results of the Mustard operation. A modification of the operation was introduced at the Aswan Heart Centre for this purpose which relies on creating new functional atria rather than the two rigid channels in the classical Mustard operation.Objectives: To evaluate the morphology and function of the neo-atria, shortly after modified mustard operation for a ‘neglected’ patient with TGA, VSD and severe pulmonary hypertension.Methods: A 6-year-old with neglected TGA, VSD and pulmonary hypertension presented with severe cyanosis, clubbing and haemoconcentration (Hb 22 g/dL), underwent the modified Aswan-Mustard operation (MAM) with rapid smooth postoperative recovery. Repeated 2D echograms and multi-slice CT scans, followed by 3D segmentation, were performed after the operation. The size, shape, and morphology of the neo-atria were measured and measurements of the patterns of instantaneous filling and emptying of the right and left ventricles were quantified.Results: The neo-systemic venous atrium consisted of three components with a combined volume of 78 mL/m2, all of which contributed to the reservoir, conduit, and importantly contractile function of the neo-atrium. The pulmonary venous atrium consisted of two components with a combined volume of 66 mL/m2. These measurements were made at atrial end diastole. The volumes of the systemic venous and the pulmonary venous diminished to 51 and 54 mL/m2, respectively, at the end atrial systole - indicating relatively preserved contractile functions.

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677 LONG-TERM RESULTS OF THE PROCESSUS VAGINALIS TRANSECTION METHOD TO PREVENT POSTRADICAL PROSTATECTOMY INGUINAL HERNIA

The Journal of Urology ◽

10.1016/j.juro.2013.02.232 ◽

2013 ◽

Vol 189 (4S) ◽

Author(s):

Yasuhisa Fujii ◽

Shinya Yamamoto ◽

Junji Yonese ◽

Hitoshi Masuda ◽

Shinji Urakami ◽

...

Keyword(s):

Inguinal Hernia ◽

Long Term Results ◽

Processus Vaginalis

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THE LONG‐TERM RESULTS OF TANNER'S “SLIDE” OPERATION FOR INGUINAL HERNIA

The Medical Journal of Australia ◽

10.5694/j.1326-5377.1966.tb72402.x ◽

1966 ◽

Vol 1 (10) ◽

pp. 392-395 ◽

Cited By ~ 2

Author(s):

J. R. Magarey

Keyword(s):

Inguinal Hernia ◽

Long Term Results

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A study of short and long term complications of prolene hernia system

International Surgery Journal ◽

10.18203/2349-2902.isj20170999 ◽

2017 ◽

Vol 4 (4) ◽

pp. 1167

Author(s):

Narayan Hebsur ◽

Ravi Shankar J. C.

Keyword(s):

Inguinal Hernia ◽

Statistical Tests ◽

Long Term Results ◽

Chronic Groin Pain ◽

Medical Sciences ◽

Post Operative Period ◽

Prolene Hernia System ◽

Period 2 ◽

Pain Symptoms

Background: Prolene hernia system was introduced in 1999, and was thought to be a revolutionary type of mesh in preventing recurrence. But studies regarding long term results and complications were sparse. Our study is one such type which sheds light into the complications of prolene hernia system and its significance in Indian scenario.Methods: 30 patients with inguinal hernia in Karnataka institute of medical sciences, Hubli, were included in the study. All of them were operated with prolene hernia system. Patients were assessed in the post-operative period and during follow-up for any complications. Appropriate statistical tests were applied.Results: 1 (3.3%) patient each had seroma and superficial surgical site infection in the post-operative period. 2 (6.7%) patients had chronic groin pain symptoms and none of them had recurrence till date.Conclusions: Based on the observations, we conclude that PHS is an effective method for open inguinal hernia repair with minimal complications. It has comparable results with lichenstein repair and other types of repairs available.

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Mid- to long-term results of SuPerLap single-port treatment in inguinal hernia

Cirugía Pediátrica ◽

10.54847/cp.2022.01.13 ◽

2022 ◽

Vol 35 (1) ◽

pp. 14-17

Author(s):

R.A. Hernández-Rodríguez ◽

M.J. Rosell Echevarría ◽

F.D. Ravelo Díaz ◽

V. Villamil ◽

E.L. Pérez Etchepare Figueroa

Keyword(s):

Inguinal Hernia ◽

Single Port ◽

Long Term Results

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Two-center Analysis of Long-term Outcomes after High Ligation Inguinal Hernia Repair in Adolescents

The American Surgeon ◽

10.1177/000313481508101229 ◽

2015 ◽

Vol 81 (12) ◽

pp. 1260-1262 ◽

Cited By ~ 4

Author(s):

Alessandra C. Gasior ◽

E. Marty Knott ◽

Arielle Ranters ◽

Shawn D. Peter ◽

Todd A. Ponsky

Keyword(s):

Inguinal Hernia ◽

Hernia Repair ◽

Recurrent Hernia ◽

High Ligation ◽

Long Term Outcomes ◽

Recurrence Rates ◽

Hernia Sac ◽

Telephone Surveys ◽

Low Incidence

High ligation of the inguinal hernia sac is standard practice for many pediatric surgeons in post-pubertal adolescents. Most adult surgeons do not use this technique to repair indirect inguinal hernias because of concerns for higher recurrence rates compared with mesh repairs. Therefore, we examined long-term outcomes of adolescent high ligation hernia repair performed by pediatric surgeons. Telephone surveys were conducted on children over 12 years old at the time of repair, and patients and/or their parents were contacted 18 months postrepair. Patients were identified from two institutions between 1998 and 2010. The incidences of reoperation, recurrence, presence of bulge, chronic pain, or numbness were determined. A total of 210 patients (40.7% response rate) were available for phone interviews at 18.6 to 159.5 months postrepair. Mean age was 14.6 ± 1.8 (range: 12.0–19.0 years). Fourteen patients had pain (6.7%) and five had numbness (2.4%). There were four (1.9%) patients with a second operation, two of which confirmed a recurrent hernia. Three patients expressed concern about possible recurrence. Two report a bulge, but have not been evaluated. Pediatric hernia repair with high sac ligation appears effective in patients anatomically similar to adults with low recurrence rate and low incidence of chronic symptoms. These data suggest that prospective trials on the adequacy of high ligation in adults are warranted.

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