scholarly journals Primary culture of human primary liver cancer tissues treated with or without transcatheter arterial embolization and establishment of a cell line

1989 ◽  
Vol 101 (1-2) ◽  
pp. 131-139
Author(s):  
Yasunori KUSAKA ◽  
Takayoshi TOKIWA ◽  
Jiro SATO ◽  
Hiroshi TSUGE ◽  
Keisuke HAMASAKI ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Primary Culture ◽  
Cell Line ◽  
Transcatheter Arterial Embolization ◽  
Primary Liver Cancer ◽  
Arterial Embolization ◽  
A Cell ◽  
Cancer Tissues

scholarly journals The Heterogeneity of Liver Cancer Metabolism

2021 ◽  
pp. 127-136
Author(s):  
Javier Salazar ◽  
Anne Le
Keyword(s):  
Risk Factors ◽  
Hepatocellular Carcinoma ◽  
Liver Cancer ◽  
Cancer Metabolism ◽  
Primary Liver Cancer ◽  
Cancer Death ◽  
The World ◽  
Advanced Stages ◽  
New Biomarkers ◽  
Cancer Tissues

AbstractPrimary liver cancer is the fourth leading cause of cancer death around the world. Histologically, it can be divided into two major groups, hepatocellular carcinoma (75% of all liver cancer) and intrahepatic cholangiocarcinoma (15% of all liver cancer) [1, 2]. Primary liver cancer usually happens in liver disease or cirrhosis patients [1], and the risk factors for developing HCC depend on the etiology [3] and the country of provenance [1]. There is an urgent need for an accurate diagnostic test given the high proportion of false positives and false negatives for alpha-fetoprotein (AFP), a common HCC biomarker [4]. Due to often being diagnosed in advanced stages, HCCrelated deaths per year have doubled since 1999 [3]. With the use of metabolomics technologies [5], the aberrant metabolism characteristics of cancer tissues can be discovered and exploited for the new biomarkers and new therapies to treat HCC [6, 7].

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