scholarly journals Chemokines Determine Local Lymphoneogenesis and a Reduction of Circulating CXCR4+ T and CCR7 B and T Lymphocytes in Thyroid Autoimmune Diseases

2003 ◽  
Vol 170 (12) ◽  
pp. 6320-6328 ◽  
Author(s):  
Maria-Pilar Armengol ◽  
Cristina B. Cardoso-Schmidt ◽  
Marco Fernández ◽  
Xavier Ferrer ◽  
Ricardo Pujol-Borrell ◽  
...  
2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Emad M. El-Shebiny ◽  
Enas S. Zahran ◽  
Sabry A. Shoeib ◽  
Eman S. Habib

Abstract Background Autoimmunity is used to cause by impairment of adaptive immunity alone, whereas autoinflammatory was originally defined as a consequence of unregulated innate immunity. So, the pathogenetic mechanisms of autoimmune diseases were well-thought-out to be mediated by B and T lymphocytes. Whereas, autoinflammatory diseases were defined as unprovoked times of inflammation with the absence of a high titre of autoantibodies. Main body of the abstract Autoimmune and autoinflammatory diseases were split into two groups, but considering the similarities, it can be considered as only one group of diseases with a large immune pathological and clinical spectrum which involves at one end pure autoimmune diseases and the other pure autoinflammatory diseases. Conclusions We can safely conclude that there is bridging between autoinflammatory and autoimmune diseases.


2019 ◽  
Vol 15 (3) ◽  
pp. 174-183
Author(s):  
Pooja Hurkat ◽  
Sourabh Jain ◽  
Richa Jain ◽  
Aakanchha Jain

Background:: The immune system is designed with great care to distinguish self from non-self, as exhibited by immune responses to different pathogens. Furthermore, the immune system has the capacity to distinguish between self from altered self in case of autoimmune diseases like cancer. Developing tumors bypass the immune system mechanism which restrains selfreactive responses. Immunotherapy is a coherent means since the immune system can eliminate a number of antigens derived from the genetic constitution of B and T lymphocytes. Our understanding of the immune system has developed a great deal. Conclusion:: This review is focused not only on the mechanism by which the immune system protects us but also on the ways in which it can inflict the body and how to modulate it with therapy. Thus, understanding the interaction of a tumor with the immune system provides insights into mechanisms that can be utilized to elicit anti-tumor immune responses. Here, we have recapitulated the function of the tumor microenvironment and immune checkpoints.


The Lancet ◽  
1975 ◽  
Vol 306 (7931) ◽  
pp. 414-415
Author(s):  
Somnate Boonpucknavig ◽  
Auranut Vuttivirojana ◽  
Wipaporn Ruangjirachuporn ◽  
Junya Siripont

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii511-iii511
Author(s):  
Jose Tarcisio Giffoni de Carvalho ◽  
Marion Schneider ◽  
Lilian Cuppari ◽  
Caren Cristina Grabulosa ◽  
Silvia Regina Manfredi ◽  
...  

2019 ◽  
Vol 209 ◽  
pp. 36-44 ◽  
Author(s):  
Atri Ghods ◽  
Abbas Ghaderi ◽  
Mahmoud Shariat ◽  
Abdol-Rasoul Talei ◽  
Fereshteh Mehdipour

2011 ◽  
Vol 1217 (1) ◽  
pp. 18-31 ◽  
Author(s):  
Lynn M. Heltemes-Harris ◽  
Mark J. L. Willette ◽  
Kieng B. Vang ◽  
Michael A. Farrar

Hereditas ◽  
2004 ◽  
Vol 119 (2) ◽  
pp. 99-103 ◽  
Author(s):  
Benkt Högstedt ◽  
Anita Karlsson ◽  
Ingrid Bratt ◽  
Anders Holmén

2003 ◽  
Vol 48 (6) ◽  
pp. 1612-1621 ◽  
Author(s):  
Fr�d�ric Lajaunias ◽  
Akinori Ida ◽  
Shuichi Kikuchi ◽  
Liliane Fossati-Jimack ◽  
Eduardo Martinez-Soria ◽  
...  

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