Loss of IFN-γ Enables the Expansion of Autoreactive CD4+ T Cells to Induce Experimental Autoimmune Encephalomyelitis by a Nonencephalitogenic Myelin Variant Antigen

Joseph J. Sabatino; John Shires; John D. Altman; Mandy L. Ford; Brian D. Evavold

doi:10.4049/jimmunol.180.7.4451

Loss of IFN-γ Enables the Expansion of Autoreactive CD4+ T Cells to Induce Experimental Autoimmune Encephalomyelitis by a Nonencephalitogenic Myelin Variant Antigen

The Journal of Immunology ◽

10.4049/jimmunol.180.7.4451 ◽

2008 ◽

Vol 180 (7) ◽

pp. 4451-4457 ◽

Cited By ~ 33

Author(s):

Joseph J. Sabatino ◽

John Shires ◽

John D. Altman ◽

Mandy L. Ford ◽

Brian D. Evavold

Keyword(s):

T Cells ◽

Experimental Autoimmune Encephalomyelitis ◽

Cd4 T Cells ◽

Autoimmune Encephalomyelitis ◽

Ifn Γ ◽

Variant Antigen ◽

Experimental Autoimmune

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The Disease-Ameliorating Function of Autoregulatory CD8 T Cells Is Mediated by Targeting of Encephalitogenic CD4 T Cells in Experimental Autoimmune Encephalomyelitis

The Journal of Immunology ◽

10.4049/jimmunol.1300452 ◽

2013 ◽

Vol 191 (1) ◽

pp. 117-126 ◽

Cited By ~ 33

Author(s):

Sterling B. Ortega ◽

Venkatesh P. Kashi ◽

Andrew F. Tyler ◽

Khrishen Cunnusamy ◽

Jason P. Mendoza ◽

...

Keyword(s):

T Cells ◽

Experimental Autoimmune Encephalomyelitis ◽

Cd8 T Cells ◽

Cd4 T Cells ◽

Autoimmune Encephalomyelitis ◽

Experimental Autoimmune

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Cathepsin L regulates pathogenic CD4 T cells in experimental autoimmune encephalomyelitis

International Immunopharmacology ◽

10.1016/j.intimp.2021.107425 ◽

2021 ◽

Vol 93 ◽

pp. 107425

Author(s):

Miho Shibamura-Fujiogi ◽

Koichi Yuki ◽

Lifei Hou

Keyword(s):

T Cells ◽

Experimental Autoimmune Encephalomyelitis ◽

Cd4 T Cells ◽

Cathepsin L ◽

Autoimmune Encephalomyelitis ◽

Experimental Autoimmune

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HLA-DQ6 (DQB1*0601)-Restricted T Cells Protect against Experimental Autoimmune Encephalomyelitis in HLA-DR3.DQ6 Double-Transgenic Mice by Generating Anti-Inflammatory IFN-γ

The Journal of Immunology ◽

10.4049/jimmunol.180.11.7747 ◽

2008 ◽

Vol 180 (11) ◽

pp. 7747-7756 ◽

Cited By ~ 19

Author(s):

Ashutosh Mangalam ◽

David Luckey ◽

Eati Basal ◽

Marshall Behrens ◽

Moses Rodriguez ◽

...

Keyword(s):

T Cells ◽

Experimental Autoimmune Encephalomyelitis ◽

Transgenic Mice ◽

Autoimmune Encephalomyelitis ◽

Ifn Γ ◽

Double Transgenic Mice ◽

Anti Inflammatory ◽

Hla Dr3 ◽

Experimental Autoimmune

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Transplanting of Mesenchymal Stem Cells May Affect Proliferation and Function of CD4+T Cells in Experimental Autoimmune Encephalomyelitis

Experimental and Clinical Transplantation ◽

10.6002/ect.2011.0197 ◽

2012 ◽

Vol 10 (5) ◽

pp. 492-500 ◽

Cited By ~ 8

Author(s):

Jingsong Zhu ◽

Junfeng Zhang ◽

Qianru Li ◽

Ying Du ◽

Baoping Qiao ◽

...

Keyword(s):

Stem Cells ◽

T Cells ◽

Mesenchymal Stem Cells ◽

Experimental Autoimmune Encephalomyelitis ◽

Cd4 T Cells ◽

Autoimmune Encephalomyelitis ◽

And Function ◽

Experimental Autoimmune

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Autoreactive Tbet-Positive CD4 T Cells Develop Independent of Classic Th1 Cytokine Signaling during Experimental Autoimmune Encephalomyelitis

The Journal of Immunology ◽

10.4049/jimmunol.1100031 ◽

2011 ◽

Vol 187 (10) ◽

pp. 4998-5006 ◽

Cited By ~ 17

Author(s):

Wen-I Yeh ◽

Ian L. McWilliams ◽

Laurie E. Harrington

Keyword(s):

T Cells ◽

Experimental Autoimmune Encephalomyelitis ◽

Cd4 T Cells ◽

Cytokine Signaling ◽

Autoimmune Encephalomyelitis ◽

Th1 Cytokine ◽

Experimental Autoimmune

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Th40 cells (CD4+CD40+ Tcells) drive a more severe form of Experimental Autoimmune Encephalomyelitis than conventional CD4 T cells

PLoS ONE ◽

10.1371/journal.pone.0172037 ◽

2017 ◽

Vol 12 (2) ◽

pp. e0172037 ◽

Cited By ~ 9

Author(s):

Gisela M. Vaitaitis ◽

Martin G. Yussman ◽

Dan M. Waid ◽

David H. Wagner

Keyword(s):

T Cells ◽

Experimental Autoimmune Encephalomyelitis ◽

Cd4 T Cells ◽

Severe Form ◽

Autoimmune Encephalomyelitis ◽

Experimental Autoimmune

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Decreased severity of experimental autoimmune encephalomyelitis during resveratrol administration is associated with increased IL-17+IL-10+ T cells, CD4− IFN-γ+ cells, and decreased macrophage IL-6 expression

International Immunopharmacology ◽

10.1016/j.intimp.2008.10.015 ◽

2009 ◽

Vol 9 (1) ◽

pp. 134-143 ◽

Cited By ~ 60

Author(s):

Toby J. Imler ◽

Thomas M. Petro

Keyword(s):

T Cells ◽

Experimental Autoimmune Encephalomyelitis ◽

Autoimmune Encephalomyelitis ◽

Ifn Γ ◽

Experimental Autoimmune

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IL-15-dependent CD8+CD122+T cells ameliorate experimental autoimmune encephalomyelitis by modulating IL-17 production by CD4+T cells

European Journal of Immunology ◽

10.1002/eji.201444675 ◽

2014 ◽

Vol 44 (11) ◽

pp. 3330-3341 ◽

Cited By ~ 26

Author(s):

Ping Yu ◽

Richard N. Bamford ◽

Thomas A. Waldmann

Keyword(s):

T Cells ◽

Experimental Autoimmune Encephalomyelitis ◽

Cd4 T Cells ◽

Autoimmune Encephalomyelitis ◽

Experimental Autoimmune

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Requirement of CD30 expression on CD4 T cells in the pathogenesis of experimental autoimmune encephalomyelitis

Journal of Neuroimmunology ◽

10.1016/j.jneuroim.2015.12.005 ◽

2016 ◽

Vol 291 ◽

pp. 39-45 ◽

Cited By ~ 3

Author(s):

Koji Shinoda ◽

Xun Sun ◽

Akiko Oyamada ◽

Hisakata Yamada ◽

Jun-ichi Kira ◽

...

Keyword(s):

T Cells ◽

Experimental Autoimmune Encephalomyelitis ◽

Cd4 T Cells ◽

Autoimmune Encephalomyelitis ◽

Experimental Autoimmune

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Analysis of Autoreactive CD4 T Cells in Experimental Autoimmune Encephalomyelitis after Primary and Secondary Challenge Using MHC Class II Tetramers

The Journal of Immunology ◽

10.4049/jimmunol.172.5.2878 ◽

2004 ◽

Vol 172 (5) ◽

pp. 2878-2884 ◽

Cited By ~ 35

Author(s):

Felix Bischof ◽

Matthias Hofmann ◽

Ton N. M. Schumacher ◽

Florry A. Vyth-Dreese ◽

Robert Weissert ◽

...

Keyword(s):

T Cells ◽

Experimental Autoimmune Encephalomyelitis ◽

Mhc Class Ii ◽

Cd4 T Cells ◽

Class Ii ◽

Autoimmune Encephalomyelitis ◽

Secondary Challenge ◽

Experimental Autoimmune

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