scholarly journals Pulmonary recurrence from prostate cancer and biochemical remission after metastasis directed therapy. A case report

2018 ◽  
Vol 90 (1) ◽  
pp. 74 ◽  
Author(s):  
Riccardo Boschian ◽  
Michele Rizzo ◽  
Lorenzo Zandonà ◽  
Carlo Trombetta ◽  
Giovanni Liguori
Keyword(s):  
Prostate Cancer ◽  
Case Report ◽  
Clinical Practice ◽  
Radical Prostatectomy ◽  
Pulmonary Metastases ◽  
Left Lung ◽  
Lower Lobe ◽  
Subsequent Reduction ◽  
Biochemical Remission ◽  
The One

We report a case of a 69-years-old man who presented with a solitary 1 cm nodule in the lower lobe of the left lung almost 3 years after radical prostatectomy for pT3aN0M0, Gleason score 4+3 disease, without evidence of osseous or lymphatic spread. Surgical resection of the pulmonary lobe confirmed the metastatic nature of the lesion, with subsequent reduction of serum PSA to undetectable levels. After 2 years from the metastasis resection, serum PSA is still undetectable, without the necessity of additional treatments. Solitary pulmonary metastases from prostate cancer (Pca) are rare in clinical practice, with only 29 previous cases described besides the one that we present.

scholarly journals Isolated non-ascitic peritoneal carcinomatosis after robotic radical prostatectomy for prostate cancer: A case report

2020 ◽  
Vol 33 ◽  
pp. 101414
Author(s):  
Michael-Abdo-Jefferson Billy El khoury ◽  
Marie Van Eycken ◽  
Thierry Roumeguère ◽  
Simone Albisinni
Keyword(s):  
Prostate Cancer ◽  
Case Report ◽  
Radical Prostatectomy ◽  
Peritoneal Carcinomatosis ◽  
Robotic Radical Prostatectomy

scholarly journals The role of resection of pulmonary metastases from prostate cancer: a case report and literature review

2013 ◽  
Vol 5 (6) ◽  
pp. 104
Author(s):  
Christopher J.D. Wallis ◽  
John C. English ◽  
S. Larry Goldenberg
Keyword(s):  
Prostate Cancer ◽  
Pulmonary Metastases ◽  
Specific Antigen ◽  
Lower Lobe ◽  
Lung Nodules ◽  
Lower Lung ◽  
Long Term Prognosis ◽  
Solitary Metastases

We report a case of a 53-year-old man who presented with twonodules in the lower lobe and one nodule in the upper lobe of theright lung almost 7 years after radical prostatectomy for pT3aN0M0,Gleason 4+5 disease, without evidence of osseous or lymphaticspread. Surgical resection of the lower lung nodules confirmedmetastases, but prostate-specific antigen did not drop to undetectablelevels. Isolated pulmonary metastases from prostate cancerare rare with only 33 previously described cases in the Englishlanguageliterature, 18 of which were solitary metastases. Wereview the principles of management, including metastasectomyand long-term prognosis.

scholarly journals Assessment of a patient-reported outcome measure in men with prostate cancer who had radical surgery: a Rasch analysis

BMJ Open ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. e035436
Author(s):  
Eva Protopapa ◽  
Jan van der Meulen ◽  
Caroline M Moore ◽  
Sarah C Smith
Keyword(s):  
Prostate Cancer ◽  
Clinical Practice ◽  
Radical Prostatectomy ◽  
Sexual Function ◽  
Rasch Analysis ◽  
Outcome Measure ◽  
Patient Reported Outcome ◽  
Patient Reported Outcome Measure ◽  
Patient Reported ◽  
Need To Evaluate

ObjectivesTo evaluate the psychometric properties (and identify specific anomalies to be resolved) of urinary and sexual function scales of the Symptom Tracking and Reporting (STAR) instrument for use in clinical practice with individual men using Rasch analysis.DesignProspective cohort study.Setting9 UK surgery centres in secondary care.Participants403 men diagnosed with prostate cancer and completed at least one questionnaire immediately before and at 1 or 3 months after radical prostatectomy.Primary and secondary outcomesSTAR instrument before surgery and 1 and 3 months afterwards.ResultsNeither scale fitted the Rasch model (both scales p<0.001). Both urinary (seven items) and sexual function (six items) had disordered thresholds, suggesting response categories are not working as intended. Both scales (three urinary items; five sexual function items) showed problems with item fit (large fit residuals, significant χ2, an inspection of item characteristic curves). Both scales showed items that were unstable over time (differential item functioning (DIF) by time). Both scales (four pairs of items in each scale) showed local response dependency (residual correlations >0.2 above the average). Internal consistency was acceptable at the group level for both scales. Targeting was poor for both scales, indicating an inadequate match between the location of items and the distribution of the patients, suggesting that the underlying constructs that the scales purport to measure are not clear.ConclusionUsing Rasch analysis as a diagnostic tool, we identified that both the urinary and the sexual function scales have issues that need to be resolved before STAR can be used with confidence in clinical practice. The sexual function scale, in particular, is unlikely to provide precise estimates for the outcomes experienced by men after radical prostatectomy. These results demonstrate the need to evaluate the suitability of any patient-reported outcome measure before implementation in routine clinical practice, preferably using modern psychometric methods.

scholarly journals Sclerosing haemangioma of the lung: A case report

2012 ◽  
Vol 1 (1) ◽  
pp. 33-36
Author(s):  
R Thapa ◽  
M Lakhey ◽  
U Shrestha
Keyword(s):  
Case Report ◽  
Chest Pain ◽  
Ct Scan ◽  
Left Lung ◽  
Lower Lobe ◽  
X Ray ◽  
Medical College ◽  
Bronchoscopic Biopsy ◽  
Chest X Ray ◽  
Sclerosing Haemangioma

Sclerosing haemangioma is a rare neoplasm of the lung which behaves in a clinically benign fashion. Herein, a case of sclerosing haemangioma of the lung in a 52 years old woman is reported. She presented with symptoms of cough and chest pain. Chest X-ray and CT scan showed a well-defined lesion in lower lobe of left lung. Bronchoscopic biopsy findings were suggestive of a carcinoid tumor. Later the tumor was removed by lobectomy. The distinctive constellation of histologic findings revealed it to be a sclerosing haemangioma. DOI: http://dx.doi.org/10.3126/jkmc.v1i1.7254 Journal of Kathmandu Medical College, Vol. 1, No. 1, Issue 1, Jul.-Sep., 2012 pp.33-36

scholarly journals Metastatic Mucinous Adenocarcinoma of the Prostate with PSA Value of 8.6 ng/mL at 5-Year-Followup after Prostatectomy, Radiotherapy, and Androgen Deprivation

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Christos Kalaitzis ◽  
Michael Koukourakis ◽  
Stilianos Giannakopoulos ◽  
Alexandra Giatromanolaki ◽  
Efthimios Sivridis ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Case Report ◽  
Radical Prostatectomy ◽  
Rare Variant ◽  
Mucinous Adenocarcinoma ◽  
Clinical Course ◽  
Malignant Potential ◽  
Androgen Deprivation ◽  
Case Presentation ◽  
Adenocarcinoma Of The Prostate

Introduction. Mucinous adenocarcinoma of the prostate is a rare variant of prostate cancer. Its malignant potential and the clinical course of the affected patients remain, by and large, controversial. No data exist about the course of metastatic mucinous adenocarcinoma of the prostate.Case Presentation. This case report describes the excellent clinical course of a 68-year-old patient with metastatic mucinous adenocarcinoma of the prostate, treated by radical prostatectomy, irradiation, and androgen deprivation.Conclusion. In our case, mucinous adenocarcinoma of the prostate does not appear to behave differently than acinar prostate cancer. Its malignant potential is dependent on its Gleason score.

scholarly journals 68Gallium-prostate-specific membrane antigen ligand positron-emission tomography or computed tomography in biochemical failure after radical prostatectomy: A case report

2017 ◽  
Vol 1 ◽  
pp. 3
Author(s):  
Irene A. Chidothe ◽  
David B. Anderson
Keyword(s):  
Prostate Cancer ◽  
Computed Tomography ◽  
Positron Emission Tomography ◽  
Case Report ◽  
Radical Prostatectomy ◽  
Biochemical Failure ◽  
Emission Tomography ◽  
Prostate Specific Membrane Antigen ◽  
Positron Emission ◽  
Specific Membrane

Biochemical failure after radical treatment for prostate cancer occurs in up to 30% – 50% of cases. Localisation of clinical disease is challenging because clinical symptoms often manifest long after the initial rise in prostate-specific antigen. The detection rates of imaging modalities such as contrasted computed tomography (CT), bone scan, magnetic resonance imaging and choline positron-emission tomography (PET) or CT, are limited. Prostate-specific membrane antigen (PSMA) ligand PET or CT is a novel imaging modality under investigation for various diagnostic and therapeutic indications in the management of prostate cancer. We present a case report illustrating how <sup><span style="font-size: small;">68</span></sup>Gallium-PSMA ligand PET or CT was used to guide management in a patient presenting with biochemical failure after radical prostatectomy.

Prostate cancer testicular metastasis: Are they underestimated? Case report and analysis of the literature

2021 ◽  
pp. 039156032110091
Author(s):  
Salvatore Smelzo ◽  
Guglielmo Mantica ◽  
Roberta Lucianò ◽  
Nazario Pio Tenace ◽  
Davide De Marchi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Case Report ◽  
Radical Prostatectomy ◽  
Rare Case ◽  
Perioperative Complications ◽  
Case Description ◽  
Accurate Evaluation ◽  
Testicular Metastasis ◽  
Pathological Analysis ◽  
Retropubic Radical Prostatectomy

Introduction: We aim to present a rare case of a patient who developed a late testicular metastasis of PCa after radical prostatectomy. Case description: A 78 years old man presenting for left testicular swelling slowly increasing of size over the last 2 months. He underwent a retropubic radical prostatectomy and extended bilateral lymphadenectomy in 2007 for prostatic adenocarcinoma. At the time of the presentation the last PSA was 0.91 ng/mL. The patient underwent a standard left orchifunicolectomy in April 2019 without intra- or perioperative complications. The pathological analysis showed a testicular metastasis of acinar adenocarcinoma. Conclusions: In conclusion, testicular metastasis from PCa are uncommon conditions. PSA evaluation and physical examination of all sites of metastasis and accurate evaluation of all signs/symptoms during the clinical visit remains crucial to the diagnosis of recurrence.

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