scholarly journals Association of aortic and main left coronary aneurysms with severe aortic insufficiency in Takayasu’s arteritis

2011 ◽  
Vol 1 (2) ◽  
pp. 26
Author(s):  
Marcelo Ferraz de Freitas ◽  
Marcelo Valladão de Carvalho ◽  
Marcelo Derbli Schafranski
Keyword(s):  
Takayasu’S Arteritis ◽  
Coronary Aneurysm ◽  
Aortic Insufficiency ◽  
Unknown Etiology ◽  
Takayasu's Arteritis ◽  
Rare Finding ◽  
Granulomatous Vasculitis ◽  
Coronary Aneurysms ◽  
Uncommon Disease ◽  
Caucasian Female

Takayasu’s arteritis is a granulomatous vasculitis of unknown etiology that affects mainly the aorta and its branches. As a result of intimal fibroproliferation, segmental stenosis, occlusion, dilatation, and aneurysmal formation of the involved vessels may develop. It is an uncommon disease and usually affects young Asian female patients during the second and third decades of life. Coronary arteries are exceptionally affected and coronary aneurysm formation is a very rare finding. We describe a case of a previously healthy 26-year-old Caucasian female whose Takayasu’s arteritis presented as a previously undescribed association of aortic and main left coronary aneurysms with severe aortic insufficiency.

Takayasu’s arteritis

2010 ◽  
pp. 2968-2973
Author(s):  
Yasushi Kobayashi
Keyword(s):  
Takayasu’S Arteritis ◽  
Middle Eastern ◽  
Aortic Insufficiency ◽  
Acute Stage ◽  
Vascular Lesions ◽  
Anatomical Location ◽  
South American ◽  
Takayasu's Arteritis ◽  
Granulomatous Vasculitis ◽  
The Brain

Takayasu’s arteritis is a chronic granulomatous vasculitis of unknown cause characterized by stenosis, occlusion, and aneurysm of large elastic arteries, mainly the aorta and its branches. It mainly affects young women, predominantly in Asian, Middle Eastern, and South American countries. Clinical presentation—symptoms in the acute stage are nonspecific, such as general fatigue and fever, which can persist for months to years. Symptoms in the chronic stage depend on the anatomical location of the vascular lesions, with typical complaints relating to ischaemia of the brain, eyes, or arms. The commonest finding on physical examination is a weak or absent pulse in one or both brachial, radial, and/or ulnar arteries. Bruits can often be heard over affected arteries. Hypertension and aortic insufficiency are strongly associated with poor prognosis....

scholarly journals Pyoderma Gangrenosum and Erythema Nodosum Revealing Takayasu’s Arteritis

2016 ◽  
Vol 8 (3) ◽  
pp. 354-357 ◽  
Author(s):  
Jonas Loetscher ◽  
Susanna Fistarol ◽  
Ulrich A. Walker
Keyword(s):  
Pyoderma Gangrenosum ◽  
Erythema Nodosum ◽  
Takayasu’S Arteritis ◽  
Skin Lesions ◽  
Takayasu's Arteritis ◽  
Young Females ◽  
Worldwide Distribution ◽  
Asian Populations ◽  
Asian Patients ◽  
Caucasian Female

We report a Caucasian female who presented with simultaneous erythema nodosum and pyoderma gangrenosum due to underlying Takayasu’s arteritis. Takayasu’s arteritis is a chronic large vessel vasculitis of unknown cause. The disease has a worldwide distribution but is most commonly seen in Asian populations. There is a strong predilection for young females. The clinical presentation is variable, but mostly derives from stenosis or occlusion of affected arteries, resulting in claudication and ischemia. Skin manifestations are observed in up to 28% of patients with Takayasu’s arteritis, with erythema nodosum reported more frequently in Caucasians. Pyoderma gangrenosum is more common in Asian patients. This report demonstrates the importance to exclude Takayasu’s arteritis in patients with such skin lesions.

Ultrasound Assessment of Takayasu's Arteritis

2005 ◽  
Vol 29 (1) ◽  
pp. 33-38
Author(s):  
Y. M. Butcher ◽  
R. L. Hetherington ◽  
H. H. Gibbs
Keyword(s):  
Takayasu’S Arteritis ◽  
Duplex Ultrasound ◽  
Carotid Bifurcation ◽  
Duplex Scanning ◽  
Wall Thickening ◽  
Takayasu's Arteritis ◽  
Ultrasound Findings ◽  
Uncommon Disease ◽  
Vascular Laboratory ◽  
Ultrasound Assessment

Introduction Atherosclerosis is the most common abnormality seen in the vascular laboratory. Rarely, other arterial diseases, such as large vessel vasculitis, are seen. We describe our experience of Takayasu's arteritis (TA). Methods The clinical and duplex ultrasound findings of six patients with TA were analyzed. Common sites of involvement and the ultrasound appearances of TA were compared with typical findings of atherosclerosis. Results The mean age of the patients was 53 yr, and all were female. TA had been present for 11.8 yr (range, 1–27 yr). All six patients underwent upper extremity duplex scanning. In all cases, abnormalities were present in the proximal and mid common carotid arteries; however, the carotid bifurcation was normal in five of six cases. The proximal subclavian artery was abnormal in five of six cases. In addition, four patients had a severe stenosis in the distal axillary/proximal brachial artery. All of these abnormalities were situated distal to the origin of the subscapular artery. All patients underwent duplex scanning of the abdominal aorta. Severe stenotic disease was present in two patients, with one of these having had a previous aortic grafting procedure. Three additional patients had aortic wall thickening without stenosis. B-mode ultrasonography demonstrated homogenous, concentric, long arterial wall thickening in all areas of abnormality in all cases. Conclusions TA is an uncommon disease affecting the large branches of the aorta. The proximal and mid common carotid and the distal axillary arteries are commonly involved, and these sites are unusual in atherosclerosis. The detection of abnormalities on duplex scanning at these sites raises the diagnostic possibility of TA.

Ascending aortic aneurysm associated with aortic insufficiency due to Takayasu’s arteritis

1999 ◽  
Vol 68 (1) ◽  
pp. 248-250 ◽  
Author(s):  
Afksendiyos Kalangos ◽  
Ary Baldovinos ◽  
Maurice Beghetti ◽  
Dominique Vala ◽  
Bernard Faidutti
Keyword(s):  
Aortic Aneurysm ◽  
Takayasu’S Arteritis ◽  
Aortic Insufficiency ◽  
Takayasu's Arteritis ◽  
Ascending Aortic Aneurysm

scholarly journals Takayasu’s Arteritis

2017 ◽  
Vol 6 (1) ◽  
pp. 48-52
Author(s):  
Sujeeb Rajbhandari
Keyword(s):  
Weight Loss ◽  
Renal Failure ◽  
Acute Phase ◽  
Takayasu’S Arteritis ◽  
Arterial Occlusion ◽  
Limb Ischemia ◽  
Unknown Etiology ◽  
Takayasu's Arteritis

Takayasu’s arteritis is a disease of unknown etiology primarily affecting women aged less than 40 years. It is mainly seen in Asians and Africans. This condition is an aorto-arteritis and involves aorta and its major branches causing segmental narrowing or dilatation. Diminished or absent pulses and hypertension are common. Constitutional symptoms, including fever and weight loss, are often accompanied by elevation of acute phase markers. Diagnosis is made usually in quiescent or “cold phase” of the disease. Long-term complications are due mainly to arterial occlusion and related damage, including limb ischemia and renal failure.

Takayasu's arteritis with unstable angina and aortic insufficiency

1995 ◽  
Vol 130 (5) ◽  
pp. 1122-1124 ◽  
Author(s):  
Salvatore Trazzera ◽  
Joseph Colasacco ◽  
Lawrence Ong
Keyword(s):  
Unstable Angina ◽  
Takayasu’S Arteritis ◽  
Aortic Insufficiency ◽  
Takayasu's Arteritis

Comparison of Clinical Features at the Onset of Takayasu’s Arteritis According to Age and Sex

2019 ◽  
Vol 18 (1) ◽  
pp. 80-86
Author(s):  
Jin Wan ◽  
Shuying Qi ◽  
Hua Liao ◽  
Weiping Ci ◽  
Yanqiu Guo ◽  
...  
Keyword(s):  
Chest Pain ◽  
Takayasu’S Arteritis ◽  
Age At Onset ◽  
Clinical Manifestations ◽  
Aortic Insufficiency ◽  
Predisposing Factors ◽  
Takayasu's Arteritis ◽  
Aortic Lesion ◽  
Patient Groups ◽  
Male Patients

Background: Takayasu’s arteritis (TA) is a large-vessel vasculitis that predominantly affects the aorta, pulmonary artery, and its main branches. The cause of TA is still unclear. Objective: To identify the clinical characteristics of TA at onset in different patient groups. Methods: The clinical manifestations, laboratory, and angiographic findings of 53 patients with TA based on age at onset and sex were retrospectively analysed. Results: The ratio of the incidence of TA in males and females was 1:4. Chest pain, reduced glomerular filtration rate (GFR), and multivessel involvement were the most common symptoms at TA onset in male patients. 17% of patients had an onset age >40 years, and the percentage of TA patients >40 years old with chest pain was significantly higher [6 (66.7%) vs 13 (29.5%) and p=0.031] than that in TA patients <40 years old. However, their renal artery involvement [1 (11.1%) vs 21 (47.7%)), p=0.042], abdominal aorta lesion [0 (0.0%) vs 16 (38.1%), p=0.030], and multiple vessel involvement [2 (22.2%) vs. 32 (72.7%), p=0.004] were significantly less evident. Multivariate analysis showed that hypertension and thoracic aortic lesion were predisposing factors for TA diagnosis [odds ratio (OR)=3.918, 95% confidence interval (CI)=1.616-1566.185, p=0.026]. For patients with aortic insufficiency (OR=3.674, 95% CI=2.734-567.621, p=0.007) or aneurysm formation (OR=7.255, 95% CI=1.23-1628.614, p=0.044), ascending aortic lesion was an independent risk factor. Furthermore, patients >40 years with chest pain but no brachial pulse should be suspected to have TA. Conclusion: Hypertension and thoracic aortic lesion are predisposing factors for the diagnosis of TA. Male with TA was more prone to present with chest pain, multivessel involvement, and reduced GFR.

scholarly journals An Unusual Association: Takayasu’s Arteritis and Tubulointerstitial Nephritis and Uveitis Syndrome

2020 ◽  
Author(s):  
Abir Derbel ◽  
Mariam Ghribi ◽  
Sameh Marzouk ◽  
Zouhir Bahloul
Keyword(s):  
Tubulointerstitial Nephritis ◽  
Takayasu’S Arteritis ◽  
Takayasu's Arteritis ◽  
Tinu Syndrome ◽  
Granulomatous Vasculitis ◽  
Unusual Association ◽  
First Case ◽  
Immune Mediated

The coexistence of two immune-mediated diseases in the same patient is unusual. Takayasu’s arteritis (TA), which is a chronic granulomatous vasculitis, was discovered in a 47-year-old woman followed for tubulointerstitial nephritis and uveitis syndrome (TINU syndrome). We present the first case of this association.

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