A Case Report of Transfusion Associated Acute Graft - Versus - Host Disease

1992 ◽  
Vol 25 (5) ◽  
pp. 1023
Author(s):  
Jae Hwan Kim ◽  
Hyung Mi Kim ◽  
Mi Kyoung Lee ◽  
Young Chul Park ◽  
Suk Min Yoon ◽  
...  
Keyword(s):  
Case Report ◽  
Graft Versus Host Disease ◽  
Host Disease ◽  
Graft Versus Host ◽  
Acute Graft

Photopheresis of a less than 10-kg child with acute graft versus host disease accompanied with hyperbilirubinemia: A case report

2018 ◽  
Vol 57 (3) ◽  
pp. 428-430 ◽  
Author(s):  
Ashraf Malek Mohammadi ◽  
Amir Hossein Norooznezhad ◽  
Jerard Seghatchian ◽  
Mohsen Nikbakht ◽  
Farhad Heshmati ◽  
...  
Keyword(s):  
Case Report ◽  
Graft Versus Host Disease ◽  
Host Disease ◽  
Graft Versus Host ◽  
Acute Graft

Acute Graft-Versus-Host-Disease in Kidney Transplantation: Case Report and Review of Literature

2009 ◽  
Vol 41 (9) ◽  
pp. 3949-3952 ◽  
Author(s):  
T. Kato ◽  
K. Yazawa ◽  
K. Madono ◽  
J. Saito ◽  
M. Hosomi ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Case Report ◽  
Graft Versus Host Disease ◽  
Review Of Literature ◽  
Host Disease ◽  
Graft Versus Host ◽  
Acute Graft

scholarly journals Acute graft-versus-host disease after human heart-lung transplantation: A case report

1997 ◽  
Vol 114 (2) ◽  
pp. 285-287 ◽  
Author(s):  
R. Pfitzmann ◽  
M. Hummel ◽  
O. Grauhan ◽  
P. Waurick ◽  
R. Ewert ◽  
...  
Keyword(s):  
Case Report ◽  
Lung Transplantation ◽  
Graft Versus Host Disease ◽  
Human Heart ◽  
Host Disease ◽  
Graft Versus Host ◽  
Acute Graft

Biosimilar infliximab administration for the management of acute graft-versus-host disease

2020 ◽  
Vol 26 (8) ◽  
pp. 2047-2051
Author(s):  
Eris Tollkuci ◽  
Paul Fitzpatrick ◽  
Amanda N Seddon ◽  
Rebecca Myers ◽  
Sunita Nathan ◽  
...  
Keyword(s):  
Case Report ◽  
Graft Versus Host Disease ◽  
Treatment Options ◽  
Cell Transplant ◽  
Hematopoietic Stem ◽  
Host Disease ◽  
Graft Versus Host ◽  
First Case ◽  
Steroid Refractory ◽  
Acute Graft

Introduction Acute graft-versus-host disease (aGVHD) is a significant immune-mediated complication of allogeneic hematopoietic stem cell transplant (HSCT). Despite prophylactic immunosuppression, the incidence of grades II–IV aGVHD post-HSCT varies from 20 to 80%. Tumor necrosis factor (TNF) is an important cytokine involved in the pathogenesis of GVHD, and medications such as infliximab (Remicade®) have been utilized as second-line treatment options in patients with steroid-refractory GHVD. Infliximab-dyyb (Inflectra®) and infliximab-qbtx (Ixifi®) are biosimilars approved by the FDA for a variety of autoimmune disorders. This is the first case report documenting the utility of infliximab-dyyb and -qbtx for the management of steroid-refractory aGVHD. Case report We report the post-transplant course of three patients treated with infliximab biosimilars as a part of therapy for management of steroid-refractory aGVHD. Management and outcome Steroid-refractory aGVHD is associated with poor prognosis and its management, as highlighted in our three patient cases, and can be very diverse often requiring different therapeutic modalities which overlap in administration. Discussion In these patients with steroid-refractory aGVHD, we were able to show that infliximab biosimilars could be used in lieu of the reference infliximab product. Although we had important limitations, this case report supports the use of anti-TNF agents in highly mortal steroid-refractory acute GI GVHD and that replacement of infliximab with its biosimilars is feasible.

scholarly journals Placenta-Derived Decidua Stromal Cells for Steroid Refractory Acute Graft-Versus-Host Disease – a Case Report from Two Patients

2021 ◽  
Vol 27 (3) ◽  
pp. S258-S259
Author(s):  
Yngvar Floisand ◽  
Hanne Scholz ◽  
Jochen Buchner ◽  
Geir Erland Tjønnfjord ◽  
Tobias Gedde-Dahl ◽  
...  
Keyword(s):  
Case Report ◽  
Graft Versus Host Disease ◽  
Stromal Cells ◽  
Host Disease ◽  
Graft Versus Host ◽  
Steroid Refractory ◽  
Acute Graft
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