scholarly journals Retrospective study on prognostic importance of serum procalcitonin and amino - terminal pro - brain natriuretic peptide levels as compared to Acute Physiology and Chronic Health Evaluation IV Score on Intensive Care Unit admission, in a mixed Intensive Care Unit population

2016 ◽  
Vol 19 (2) ◽  
pp. 256 ◽  
Author(s):  
Chitra Mehta ◽  
Babita Dara ◽  
Yatin Mehta ◽  
AliM Tariq ◽  
GeorgeV Joby ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Retrospective Study ◽  
Intensive Care Unit Admission ◽  
Brain Natriuretic Peptide ◽  
Health Evaluation ◽  
Intensive Care Unit Population ◽  
Amino Terminal ◽  
Mixed Intensive Care Unit ◽  
Prognostic Importance

PROGNOSTIC IMPORTANCE OF INCREASED PLASMA AMINO-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE LEVELS IN A LARGE NONCARDIAC, GENERAL INTENSIVE CARE UNIT POPULATION

Shock ◽  
2009 ◽  
Vol 31 (4) ◽  
pp. 342-347 ◽  
Author(s):  
Anastasia Kotanidou ◽  
Petros Karsaliakos ◽  
Marinella Tzanela ◽  
Irini Mavrou ◽  
Petros Kopterides ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
General Intensive Care Unit ◽  
Intensive Care Unit Population ◽  
Amino Terminal ◽  
Prognostic Importance

scholarly journals Blood Glucose Control in the Trauma Patient

2009 ◽  
Vol 3 (6) ◽  
pp. 1373-1376 ◽  
Author(s):  
James Eakins
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Trauma Patient ◽  
Glucose Control ◽  
Blood Glucose Control ◽  
Intensive Care Unit Population ◽  
Trauma Population ◽  
Mixed Intensive Care Unit ◽  
Response To Stress ◽  
Improved Outcome

Hyperglycemia can be a significant problem in the trauma population and has been shown to be associated with increased morbidity and mortality. Hyperglycemia in the trauma patient, as in other critically ill patients, is caused by a hypermetabolic response to stress and seems to be an entity of its own rather than simply a marker. Although several early studies in a mixed intensive care unit population indicated that insulin protocols aimed at strict glucose control improved outcome, later studies did not support this and, in fact, encountered increased complications due to hypoglycemia. More recent studies in the trauma population, while supporting the correlation between hyperglycemia and increased mortality, seemed to indicate that protocols aimed at moderate glucose control improved outcome while limiting the incidence of hypoglycemic complications.

scholarly journals Increased rates of intensive care unit admission in patients with Mycoplasma pneumoniae : a retrospective study

2016 ◽  
Vol 22 (8) ◽  
pp. 711-714 ◽  
Author(s):  
T. Khoury ◽  
S. Sviri ◽  
A.A. Rmeileh ◽  
A. Nubani ◽  
A. Abutbul ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Retrospective Study ◽  
Intensive Care Unit Admission ◽  
Mycoplasma Pneumoniae

scholarly journals Letter to Editor: Clinical characteristics and prognostic factors for intensive care unit admission of patients with COVID-19: retrospective study using machine learning and natural language processing. (Preprint)

2021 ◽  
Author(s):  
Francisco Martos Pérez ◽  
Ricardo Gomez Huelgas ◽  
María Dolores Martín Escalante ◽  
José Manuel Casas Rojo
Keyword(s):  
Artificial Intelligence ◽  
Machine Learning ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Prognostic Factors ◽  
Retrospective Study ◽  
Intensive Care Unit Admission ◽  
Language Processing ◽  
Clinical Characteristics ◽  
Microbiological Diagnosis

UNSTRUCTURED Letter to Editor. Comment to “Clinical characteristics and prognostic factors for intensive care unit admission of patients with COVID-19: retrospective study using machine learning and natural language processing” publicado por Izquierdo et al en Journal of Medical Internet Research Dear Sir, The article by Izquierdo et al published in the recent issue of Journal of Medical Internet Research (1) employed a combination of conventional and machine-learning tools to describe the clinical characteristics of patients with COVID-19 and the factors that predict intensive care unit (ICU) admission. We would like to make some comments about its design. The authors should have provided the proportion of patients with positive microbiological diagnosis. If the artificial intelligence software’s capacity for retrieving this information is limited in some way, this should be explained. The classification bias introduced by the lack of microbiological confirmation may have been significant, since the study includes patients from 1 January 2020. Although some undiagnosed cases have likely been present prior to the first declared case (1st march 2020)(2) in Castilla-La Mancha, it is improbable that there were many of them. ICU admissions are related to many factors not addressed in the study. The decision not to admit a patient to the ICU because of short life expectancy, low quality of life, or high burden of comorbidities may have had a great impact during the first wave of the COVID-19 pandemic, when a scarcity of ICU beds was manifested in some regions of Spain. The 6,1% ICU admission rate reported by the authors was 36% lower than the 8,3% reported in a national survey of 15111 patients from 150 hospitals in Spain(3). We could hypothesize that the patients included in the study had a milder disease. However, given the absence of microbiological diagnosis in an unknown percentage of patients, inclusion of a significant proportion of patients without a real COVID-19 diagnosis cannot be ruled out. These doubts could have been resolved if a microbiological diagnosis had been a requisite for inclusion. The mortality rate, the most robust and relevant endpoint, should also been reported and the factors related to it analysed. Artificial intelligence is having an increasing impact on the rate of health care information processing. However, minimization of selection and classification biases should be guaranteed in the design of investigations. In this case, this could have been achieved by including only microbiologically confirmed cases and prolonging the period of inclusion, since most of the COVID-19 cases emerged after the end date of the study inclusion period. These changes in the design would have allowed for a better evaluation of the performance of artificial intelligence techniques, making the results obtained in the sample closer to those of real population.   Bibliography 1. Izquierdo JL, Ancochea J; Savana COVID-19 Research Group, Soriano JB. Clinical Characteristics and Prognostic Factors for Intensive Care Unit Admission of Patients With COVID-19: Retrospective Study Using Machine Learning and Natural Language Processing. J Med Internet Res. 2020;22(10):e21801. Published 2020 Oct 28. doi:10.2196/21801. PMID: 33090964 2. Europa Press (2020, march 1st). Un varón de 62 años ingresado en Guadalajara, primer caso positivo por coronavirus en C-LM. Retrieved 2020, January 8th. https://www.europapress.es/castilla-lamancha/noticia-varon-62-anos-ingresado-guadalajara-primer-caso-positivo-coronavirus-lm-20200301103741.html 3. Casas-Rojo JM, Antón-Santos JM, Millán-Núñez-Cortés J, et al. Clinical characteristics of patients hospitalized with COVID-19 in Spain: Results from the SEMI-COVID-19 Registry. Características clínicas de los pacientes hospitalizados con COVID-19 en España: resultados del Registro SEMI-COVID-19. Rev Clin Esp. 2020;220(8):480-494. doi:10.1016/j.rce.2020.07.003. PMID: 32762922

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