Admission blood glucose level as a potential indicator for short-term mortality and morbidity after myocardial infarction

Background: The present study was design to assess the level of altered lipid profile, lipoprotein sub fractions, oxidative stress and antioxidants in coronary artery disease with type-2 diabetes mellitus’s patients and non diabetic patients. Methods: This case–control study included 300 subjects; out of which, 100 subjects were with normal blood glucose level and with normal ECG (Normal, N), 100 subjects were with normal blood glucose level and AMI (non-diabetic and AMI, N-AMI) and 100 subjects were with diabetes and AMI (Diabetic and AMI, D-AMI) Results: D-AMI individuals had high level of total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL), and low level of high density lipoprotein (HDL) in comparison to N-AMI individuals. The cardiac markers such as Troponin I, creatine phosphokinase (CPK), creatine kinase-MB (CK-MB), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), and C-reactive protein (CRP) levels were significantly increased in patients suffering from myocardial infarction with diabetes mellitus (DM) compared to patients of myocardial infarction without DM. The antioxidant superoxide dismutase (SOD) and glutathione (GSH) were lower in D-AMI patients than in N-AMI. However, levels of malondialdehyde (MDA) and catalase (CAT) were higher in D-AMI than in N-AMI controls. Conclusion: Our study suggested that patients with D-AMI have elevated cardiac markers and reduced antioxidants levels as compared to N-AMI patient. Keywords: Diabetes Mellitus, Acute Myocardial Infarction, Creatine Phosphokinase, Glutathione

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Acute myocardial infarction. Prognostic value of white blood cell count and blood glucose level

JAMA ◽

10.1001/jama.233.3.266 ◽

1975 ◽

Vol 233 (3) ◽

pp. 266-267 ◽

Cited By ~ 1

Author(s):

B. Modan

Keyword(s):

Myocardial Infarction ◽

Acute Myocardial Infarction ◽

Blood Glucose ◽

Blood Cell ◽

Blood Glucose Level ◽

Cell Count ◽

Glucose Level ◽

White Blood Cell Count ◽

Prognostic Value ◽

Blood Cell Count

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The Effect of Intense, Short-Term Topical Dexamethasone Disodium Phosphate Eyedrops on Blood Glucose Level in Diabetic Patients

Ophthalmologica ◽

10.1159/000107505 ◽

2007 ◽

Vol 221 (6) ◽

pp. 426-429 ◽

Cited By ~ 2

Author(s):

George D. Kymionis ◽

Theoni Panagiotoglou ◽

Miltiadis K. Tsilimbaris

Keyword(s):

Blood Glucose ◽

Blood Glucose Level ◽

Glucose Level ◽

Diabetic Patients ◽

Short Term ◽

Disodium Phosphate

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The Relationship between Elevated Pre-procedural Random Blood Glucose Level and Periprocedural Myocardial Injury in Patients Undergoing Elective Percutaneous Coronary Intervention

QJM ◽

10.1093/qjmed/hcab090.030 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Nehal Badr Elnahhas ◽

Khaled El-Menyawi ◽

Ahmad Elsayed Mostafa ◽

Mostafa El Nozahi

Keyword(s):

Myocardial Infarction ◽

Blood Glucose ◽

Blood Glucose Level ◽

Glucose Level ◽

Myocardial Injury ◽

Coronary Intervention ◽

P Value ◽

Elective Percutaneous Coronary Intervention ◽

Percutaneous Coronary ◽

The Relationship

Abstract Background Regardless of the diabetic status of patients with coronary artery disease, both hyperglycemia and hypoglycemia are adversely associated with cardiovascular events. Numerous studies have concluded that hyperglycemia is common in diabetic and non-diabetic patients with STelevation myocardial infarction (STEMI) and is associated with a higher risk of death and in-hospital complications. Aim and Objectives The aim of this study is to assess the relationship between elevated preprocedural random blood glucose level and peri-procedural myocardial injury in patients undergoing elective percutaneous coronary intervention. Patients and Methods This Cohort study included 110 patients who presented with chronic coronary syndrome to the cardiology department of Ain Shams university hospitals and underwent elective PCI. They were divided into 2 equal groups, 55 as hyperglycemic group and 55 as euglycemic group. Blood glucose level was measured immediately before the procedure. Blood samples for cardiac troponin (I) were obtained before the procedure and 12 hours after the procedure. Results There was statistically significant difference between the two groups regarding incidence of both myocardial infarction and myocardial injury, both being higher among the hyperglycemic group (P-value: 0.022) &(P-value: 0.001) respectively. All five patients who had myocardial infarction belonged to the hyperglycemic group. 23 patients with myocardial injury belonged to the hyperglycemic group while only 7 patients with myocardial injury belonged to the euglycemic group. Conclusion We conclude that abnormally high pre-procedural plasma glucose levels in patients undergoing coronary angioplasty are associated with an increased incidence of peri-procedural myocardial injury and infarction in patients undergoing elective PCI.

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