Objective: Objective: To evaluate the applications of dexmedetomidine given composite dezocine spinal anesthesia in patients undergoing total hip replacement surgery. Methods: 120 cases ASA â… ~ â…¡ grade elective surgery THA patients were divided into group A (n=40), group B (n=40), C group (n=40) from June 2015 to June 2016.Group A were routined with endotracheal intubation operationï¼›Group B were gap into the line L 2-3 spinal anesthesia, anesthesia after a fixed pumping 0.2 mg dezocine a mixture of 3 ml ï¼› Group C were threatmented with dextrose infusion 3μg Mi Ding mixture 3.5 ml. The levels of mean arterialpressure (MAP ), heart rate (HR), oxygen saturation (SPO 2 ), end-tidal carbon dioxide (PETCO 2 ) and other hemodynamic parameters and plasma epinephrine (E), norepinephrine (NE), malondialdehyde (MDA) of three groups before and after 10 min of anesthesia 5min(T 0 ), of anesthesia (T 1 ), at the start of surgery (T 2 ), 1 Xiaoshi (T 3 ) after completion of anesthesia, the end of the surgery (T 4 ).The anesthetic complications occur of three groups were compared. Results: The levels of MAP, HR, SPO 2 , PETCO 2 , E, NE, MDA in T 1 ~ T 4 time were increased than T 0 stage (P<0.05).The levels of MAP, HR, SPO 2 , PETCO 2 , E, NE, MDA in T 1 ~ T 4 time of Groups A were increased than Groups B，Group C (P<0.05).The levels of MAP, HR, SPO 2 , PETCO 2 , E, NE, MDA in T 1 ~ T 4 time of Groups A and Groups B were compared. The cognitive disorders, nausea, vomiting, restlessness, chills, a high incidence of respiratory depression of Group A were higher than Group B, Group C (P<0.05),will high incidence of respiratory depression of Group B were higher than Groups C (P<0.05). Conclusion: dexmedetomidine given composite dezocine spinal anesthesia can effectively stabilize hemodynamics THA patients and reduce patient stress and blood vessels, its low incidence of postoperative complications, worthy of promotion application.
The Applications of Dexmedetomidine Given Composite Dezocine Spinal Anesthesia in Patients Undergoing Total Hip Replacement Surgery