scholarly journals Penile metastasis of urothelial carcinoma diagnosed by fine-needle aspiration

CytoJournal ◽  
2009 ◽  
Vol 6 ◽  
pp. 10 ◽  
Author(s):  
Gilda da Cunha Santos ◽  
Marcia Lanzoni de Alvarenga ◽  
Vinicius Freitas Borlot ◽  
Michel Antonio Kiyota Moutinho ◽  
Marcello Fabiano de Franco

Penile neoplasms are rare and can be primary or represent metastasis or local recurrence. The most common primary cancer of the penis is squamous cell carcinoma, accounting for 95% of all cancers. In spite of the rich vascularity of the organ, penile metastases are uncommon. Cutaneous metastasis of urothelial carcinoma (UC) is extremely rare and generally accepted as the late manifestation of a systemic spread. By 1998, approximately 500 cases of penile metastasis had been reported worldwide. However, only few case reports and series of fine-needle aspiration cytology (FNAC) of penile tumors have been documented. We report a case of penile metastasis from UC diagnosed by FNAC and describe the cytomorphological findings with an emphasis on cercariform cells. Although not commonly used, FNA of penile nodules can be effective in diagnosing recurrence or metastasis and avoiding surgical procedures, thus being an excellent initial procedure in the diagnostic approach.

2011 ◽  
Vol 40 (2) ◽  
pp. 173-178 ◽  
Author(s):  
R. L. Cantley ◽  
U. Kapur ◽  
L. Truong ◽  
D. Cimbaluk ◽  
G. A. Barkan ◽  
...  

2018 ◽  
Vol 12 (1) ◽  
Author(s):  
Diogo Turiani Hourneaux De Moura ◽  
Martin Coronel ◽  
Igor Braga Ribeiro ◽  
Galileu Ferreira Ayala Farias ◽  
Maria Auxiliadora Choez ◽  
...  

2018 ◽  
Vol 7 (1) ◽  
pp. 218-221
Author(s):  
Rusella Mirza ◽  
Steven Ellsworth ◽  
Judy King ◽  
Guillermo Sangster ◽  
Mingxia Shi

2014 ◽  
Vol 59 (1) ◽  
pp. 113-117 ◽  
Author(s):  
Oleksandr Yergiyev ◽  
Alok Mohanty ◽  
Sheilah Curran-Melendez ◽  
Carmen R. Latona ◽  
Rama Bhagavatula ◽  
...  

Background: Kaposi sarcoma (KS) is a vascular neoplasm associated with human herpesvirus 8 (HHV-8). Skin and mucous membranes are the most common sites, but other organs may be involved. Skeletal KS is rare and occurs either by direct spread of mucocutaneous lesions or through dissemination. Patients present with bone pain and lytic lesions for which they may undergo fine-needle aspiration (FNA). While there are about 70 published case reports of skeletal KS, there is limited literature specifically describing its cytomorphology. Our literature search yielded only a single prior reported case of FNA biopsy of skeletal KS in a Nigerian AIDS patient. Case: We present a case of disseminated KS of the axial skeleton in a 45-year-old African-American man with AIDS which was diagnosed on FNA cytologic examination. The patient presented with multiple lytic lesions in the axial skeleton. The aspirate, core-needle biopsy and touch imprint cytology of a bone lesion demonstrated clusters of spindle and epithelioid cells in radial and streaming arrangement with indistinct intercytoplasmic borders, elongated nuclei, fine chromatin and inconspicuous nucleoli. Immunohistochemical studies revealed positivity for HHV-8 and vascular markers. The cytomorphologic and ancillary features of the case are presented and discussed.


2021 ◽  
Vol 156 (Supplement_1) ◽  
pp. S38-S38
Author(s):  
J Hwang ◽  
S McDowell ◽  
B Cole ◽  
A R Huber ◽  
C Reyes

Abstract Introduction/Objective Glomus bodies reside in the stratum reticularis of the dermis as well as in visceral organs. Their functions involve temperature and blood pressure regulation. The incidence of glomus tumors is approximately 1.5%, occur more frequently in women, and generally manifest during the third to fifth decade of life. A majority of glomus tumors are diagnosed by biopsy and excision. At least 19 case reports exist in the literature where glomus tumors are diagnosed by fine-needle aspiration (FNA). We add to this growing literature by discussing a case report involving the cytologic findings of an FNA-diagnosed glomus tumor. Methods/Case Report A 66-year-old female presented with left second toe pain for 41 years but worsening in the past several months. Physical exam revealed 5/5 muscle strength in her toes without loss of sensation. There was no edema, erythema, nor ecchymosis. Pain was notably out of proportion when palpating her second nailbed. Magnetic resonance imaging (MRI) with contrast was performed revealing a 1.1 x 1.0 x 0.9 cm circumscribed, ovoid mass involving the dorsal aspect of the second toe distal phalanx along its dorsal margin (Figure 1). The patient underwent fine needle aspiration and biopsy. Cytologic findings included clusters of uniform cells with round to oval nuclei and scant cytoplasm. There was spindling of cells noted in some of the clusters. Cells were surrounded by thick wisps of magenta colored myxoid material reminiscent of a pleomorphic adenoma (Figure 2). Biopsy showed uniform cells surrounding capillaries. Immunohistochemistry performed on the biopsy showed that lesional cells were positive for alpha-smooth muscle actin (SMA). A diagnosis of glomus tumor was made. Amputation was performed with clear margins. Results (if a Case Study enter NA) NA Conclusion Glomus tumor is a rare tumor that is usually diagnosed on biopsy; however, it has distinct cytologic features that can aid in its diagnosis on fine needle aspirations.


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