scholarly journals Correlation of serum antithyroid microsomal antibody and autologous serum skin test in patients with chronic idiopathic urticaria

2015 ◽  
Vol 6 (4) ◽  
pp. 248 ◽  
Author(s):  
SnehalBalvant Lunge ◽  
Sushil Pande ◽  
Milind Borkar
2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Hayder R. Al-Hamamy ◽  
Ammar F. Hameed ◽  
Asaad S. Abdulhadi

Background. Chronic urticaria is defined as urticaria persisting daily for more than six weeks. A significant number of patients had autoimmune basis where autologous serum skin test is widely used for detection of chronic autoimmune urticaria. Objectives. To estimate the frequency of autoimmune urticarial in Iraqi patients utilizing the autologous serum skin test and to evaluate its results with the variable clinical features of chronic idiopathic urticaria. Methods. In this prospective study, 54 patients with chronic idiopathic urticaria were investigated with autologous serum skin test where its results were examined with the different clinical parameters of chronic autoimmune urticaria. Results. Twenty two patients (40.7%) out of 54 patients with chronic idiopathic urticarial had positive autologous serum skin test. Statistical analysis of the clinical variables did not show a significant difference between patients with positive and negative autologous serum skin test except for the distribution of wheals on the face and extremities which was significantly associated with positive autologous serum skin test results (P value 0.004). Conclusion. Autologous serum skin test is a simple, office-based test for detecting chronic autoimmune urticaria patients who have no distinctive clinical features differentiating them from chronic idiopathic urticaria patients.


2011 ◽  
Vol 7 (Suppl 2) ◽  
pp. A10 ◽  
Author(s):  
Soheyla Alyasin ◽  
Ali Asghar Karimi ◽  
Ali Amiri ◽  
Mohammad Javad Ehsaei ◽  
Fariborz Ghaffarpasand

2010 ◽  
Vol 71 ◽  
pp. S107
Author(s):  
Zamir Calamita ◽  
Marcelo O. Ruiz ◽  
Marcia Gamberini ◽  
Dione G. Arevalo ◽  
Wilson Baleotti ◽  
...  

Author(s):  
Rashmi Jindal ◽  
Samarjit Roy ◽  
Prateek Nagrani

Background: Chronic idiopathic urticaria is a subset of urticaria where no known trigger is identifiable. Almost half of these patients have an autoimmune basis of their disease. Autologous serum skin test (ASST) is an easy to perform test to identify this subgroup. However, frequency and association of positive ASST with other markers of autoimmunity remains to be studied. The present study was aimed to find out the same.Methods: Chronic idiopathic urticaria patients were divided into two groups on the basis of ASST. These were further compared for their clinical characteristics including age, gender, duration of disease and urticaria activity score. Also investigation profile including serum IgE levels, anti TPO antibodies, antiTSH and antinuclear antibodies were compared.Results: There were no statistical differences in the age, gender, duration of disease and urticaria activity score in the ASST positive and negative patients. Serum IgE levels though lower in ASST positive group were not statistically different. Frequencies of AntiTPo antibodies, antiTSH and antinuclear antibodies were also comparable in the two groups.Conclusions: ASST positive and negative groups can’t be distinguished clinically. Also autoimmunity was found to be associated with both ASST positive and negative groups.


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