Can ovarian stromal blood flow predict the response to stimulation in polycystic ovary syndrome patients undergoing infertility treatment

2021 ◽  
Vol 8 (2) ◽  
pp. 152
Author(s):  
Ruchika Sood ◽  
Bharti Jain ◽  
Maansi Jain
2020 ◽  
Author(s):  
Ada Admin ◽  
Solvejg L. Hansen ◽  
Kirstine N. Bojsen-Møller ◽  
Anne-Marie Lundsgaard ◽  
Frederikke L. Hendrich ◽  
...  

Women with polycystic ovary syndrome (PCOS) have been shown to be less insulin sensitive compared with control women, independent of BMI. Training is associated with molecular adaptations in skeletal muscle improving glucose uptake and metabolism in both healthy and type 2 diabetic individuals. In the present study, lean, hyperandrogenic women with PCOS (n=9) and healthy controls (CON, n=9) completed 14 weeks of controlled and supervised exercise training. In CON, the training intervention increased whole body insulin action by 26% and insulin-stimulated leg glucose uptake by 53%, together with increased insulin-stimulated leg blood flow and a more oxidative muscle fiber type distribution. In PCOS, no such changes were found, despite similar training intensity and improvements in maximal oxygen uptake. In skeletal muscle of CON, but not PCOS, training increased GLUT4 and HKII mRNA and protein expressions. These data suggest that the impaired increase in whole body insulin action in women with PCOS with training is caused by an impaired ability to upregulate key glucose handling proteins for insulin-stimulated glucose uptake in skeletal muscle, and insulin-stimulated leg blood flow. Still, other important benefits of exercise training appeared in women with PCOS, including an improvement of the hyperandrogenic state.


2015 ◽  
Vol 18 (6) ◽  
pp. 300-303 ◽  
Author(s):  
Rasekhjahromi Athar ◽  
Maalhagh Mehrnoosh ◽  
Hosseinpoor Masoumeh ◽  
Farhang Hooshmand ◽  
Alavi Fatemeh

2019 ◽  
Vol 32 (4) ◽  
pp. 1371
Author(s):  
HusseinM A Esmaeel ◽  
MehanyM Abd EL-Sattar ◽  
OsamaA EL-Kelany ◽  
Alaa EL-DinF EL-Halaby

1999 ◽  
Vol 78 (3) ◽  
pp. 212-216
Author(s):  
Margareta Fridström ◽  
Peter Sjöblom ◽  
Maria Granberg ◽  
Torbjörn Hillensjö

2001 ◽  
Vol 15 (2) ◽  
pp. 142-149 ◽  
Author(s):  
G. Loverro ◽  
M. Vicino ◽  
F. Lorusso ◽  
A. Vimercati ◽  
P. Greco ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document