Invasive solid papillary carcinoma: Report of the  first case presenting as an occult breast carcinoma in a male

Abstract We report the case of a 78-year-old man who developed a breast mass 12 months after hormonal therapy for palliation of prostatic adenocarcinoma. On histologic and immunohistochemical examination, the breast tumor revealed a unique collision tumor composed of metastatic prostatic adenocarcinoma and solid papillary breast carcinoma.

Download Full-text

Invasive solid papillary carcinoma with invasive lobular and invasive breast carcinoma, no special type: a rare association

BMJ Case Reports ◽

10.1136/bcr-2021-243628 ◽

2021 ◽

Vol 14 (5) ◽

pp. e243628

Author(s):

Rashim Sharma ◽

Balamurugan Thirunavukkarasu ◽

Poonam Elhence ◽

Jeewan Ram Vishnoi

Keyword(s):

Breast Carcinoma ◽

Papillary Carcinoma ◽

Type A ◽

Invasive Breast Carcinoma ◽

Rare Association ◽

Solid Papillary Carcinoma

Download Full-text

Imaging and Histopathology Correlation of Solid Papillary Carcinoma of the Breast : A Review of Four Cases

IIUM Medical Journal Malaysia ◽

10.31436/imjm.v14i1.463 ◽

2020 ◽

Vol 14 (1) ◽

Author(s):

Sharifah MIA ◽

Azwini M ◽

Nordashima AS

Keyword(s):

Breast Carcinoma ◽

Papillary Carcinoma ◽

Core Biopsy ◽

Doppler Signal ◽

Excision Biopsy ◽

Histological Findings ◽

Carcinoma Of The Breast ◽

Rare Type ◽

Solid Papillary Carcinoma

Solid papillary breast carcinoma is a rare type of breast carcinoma. We present four cases which highlight the radiological and histological findings of solid papillary carcinoma. Mammogram supplemented with ultrasound played an important role in detecting solid papillary carcinomas which usually presents as intraductal lesions or intracystic mass with Doppler signal. Excision biopsy is a better option than core biopsy as the latter modality may not be representative and the diagnosis of solid papillary breast carcinoma may be missed.

Download Full-text

A case report of unique breast carcinoma in elderly female. Solid papillary carcinoma with signet ring cells and neuroendocrine differentiation.

The Journal of the Japanese Society of Clinical Cytology ◽

10.5795/jjscc.37.181 ◽

1998 ◽

Vol 37 (2) ◽

pp. 181-185

Author(s):

Yukari NAITO ◽

Emiko NAKAMURA ◽

Kyoichi MIYAGAWA ◽

Toshio SHIMIZU ◽

Kenji KAWAGUCHI ◽

...

Keyword(s):

Case Report ◽

Breast Carcinoma ◽

Papillary Carcinoma ◽

Neuroendocrine Differentiation ◽

Signet Ring Cells ◽

Elderly Female ◽

Solid Papillary Carcinoma ◽

Signet Ring

Download Full-text

Primary occult breast carcinoma: A clinicopathological challenge

10.26226/morressier.596cd2b6d462b80292387111 ◽

2017 ◽

Author(s):

Carlos Andrés Montenegro Sáchica

Keyword(s):

Breast Carcinoma ◽

Occult Breast Carcinoma

Download Full-text

Invasive solid papillary carcinoma with neuroendocrine differentiation of the breast: a case report and literature review

Surgical Case Reports ◽

10.1186/s40792-020-00905-x ◽

2020 ◽

Vol 6 (1) ◽

Author(s):

Xue Lin ◽

Yoshiaki Matsumoto ◽

Tomomi Nakakimura ◽

Kazuo Ono ◽

Shigeaki Umeoka ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

Papillary Carcinoma ◽

Neuroendocrine Differentiation ◽

Solid Papillary Carcinoma

Download Full-text

Synchronous intrathyroidal parathyroid carcinoma and thyroid carcinoma: case report and review of the literature

BMC Endocrine Disorders ◽

10.1186/s12902-021-00724-7 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Nadia De Falco ◽

Giuseppe Santangelo ◽

Fabrizio Chirico ◽

Angelo Cangiano ◽

Maria Giulia Sommella ◽

...

Keyword(s):

Literature Review ◽

Thyroid Carcinoma ◽

Papillary Carcinoma ◽

Parathyroid Carcinoma ◽

Malignant Tumors ◽

Gamma Probe ◽

Differentiated Thyroid Carcinoma ◽

Thyroid Carcinomas ◽

First Case ◽

Well Differentiated

Abstract Background Parathyroid carcinoma is a rare endocrine malignancy, rarer when synchronous with a non medullary well differentiated thyroid carcinoma. Parathyroid carcinoma accounts of 0.005% of all malignant tumors and it is responsible for less than 1% of primary hyperparathyroidism. The intrathyroidal localization of a parathyroid gland is not frequent with a reported prevalence of 0.2%. Carcinoma of parathyroids with intrathyroidal localization represents an even rarer finding, reported in only 16 cases described in literature. The rare constellation of synchronous parathyroid and thyroid carcinomas has prompted us to report our experience and perform literature review. Case presentation We herein report a case of a 63-years-old man with multinodular goiter and biochemical diagnosis of hyperparathyroidism. Total thyroidectomy with radio-guide technique using gamma probe after intraoperative sesta-MIBI administration and intraoperative PTH level was performed. The high radiation levels in the posterior thyroid lobe discovered an intrathyroidal parathyroid. Microscopic examination revealed a parathyroid main cell carcinoma at the posterior thyroidal left basal lobe, a classic papillary carcinoma at the same lobe and follicular variant of papillary carcinoma at the thyroidal right lobe. To the best of our knowledge, this is the first case documenting a synchronous multicentric non medullary thyroid carcinomas and intrathyroidal parathyroid carcinoma. Conclusions Our experience was reported and literature review underlining challenging difficulties in diagnostic workup and surgical management was carried out.

Download Full-text

Use of immunohistochemical analysis of CK5/6, CK14, and CK34betaE12 in the differential diagnosis of solid papillary carcinoma in situ from intraductal papilloma with usual ductal hyperplasia of the breast

SAGE Open Medicine ◽

10.1177/2050312118811542 ◽

2018 ◽

Vol 6 ◽

pp. 205031211881154 ◽

Cited By ~ 3

Author(s):

Ichiro Maeda ◽

Shinya Tajima ◽

Yoshihide Kanemaki ◽

Koichiro Tsugawa ◽

Masayuki Takagi

Keyword(s):

Differential Diagnosis ◽

Papillary Carcinoma ◽

Carcinoma In Situ ◽

Immunohistochemical Staining ◽

Immunohistochemical Analysis ◽

Intraductal Papilloma ◽

Solid Papillary Carcinoma ◽

Usual Ductal Hyperplasia ◽

Ductal Hyperplasia

Objectives: The aim of this study was to use immunohistochemistry to differentiate solid papillary carcinoma in situ from intraductal papilloma with usual ductal hyperplasia (IPUDH). Three types of high-molecular-weight cytokeratins (CKs) – CK5/6, CK14, and CK34betaE12 – were targeted. Methods: We studied 17 patients with solid papillary carcinoma in situ and 18 patients with IPUDH diagnosed by at least two pathologists. Immunohistochemical analyses used antibodies to CK5/6, CK14, and CK34betaE12 to make the differential diagnosis of solid papillary carcinoma in situ versus IPUDH. Immunohistochemical staining was scored as 0–5 using Allred score. Results: Immunohistochemistry with CK5/6 and CK14 antibodies produced scores of 0–3 in all patients with solid papillary carcinoma in situ and 2–5 in all patients with IPUDH. Immunohistochemical staining with CK34betaE12 antibody produced scores of 1–3 in all patients with solid papillary carcinoma and 3–5 in all patients with IPUDH. In tissues from patients with IPUDH, significantly more cells were stained with CK34betaE12 than CK5/6 ( p < 0.05) or CK14 ( p < 0.05). Conclusion: The immunoreactivity of CK5/6, CK14, and CK34betaE12 antibodies was useful to differentiate solid papillary carcinoma in situ from IPUDH. CK34betaE12 is especially useful for distinguishing solid papillary carcinoma from IPUDH.

Download Full-text