scholarly journals Phylodynamic pattern of genetic clusters, paradigm shift on spatio-temporal distribution of clades, and impact of spike glycoprotein mutations of SARS-CoV-2 isolates from India

2021 ◽  
Vol 13 (4) ◽  
pp. 164
Author(s):  
SatishSrinivas Kitambi ◽  
Srinivasan Sivasubramanian ◽  
Vidya Gopalan ◽  
Kiruba Ramesh ◽  
Padmapriya Padmanabhan ◽  
...  
Keyword(s):  
Paradigm Shift ◽  
Temporal Distribution ◽  
Spike Glycoprotein ◽  
Genetic Clusters ◽  
Spatio Temporal

scholarly journals Phylodynamic Pattern of Genetic Clusters, Paradigm Shift on Spatio-temporal Distribution of Clades, and Impact of Spike Glycoprotein Mutations of SARS-CoV-2 Isolates from India

2021 ◽  
Author(s):  
Siva Subramanian ◽  
Satish Kitambi
Keyword(s):  
Paradigm Shift ◽  
Immune Escape ◽  
Temporal Distribution ◽  
High Morbidity ◽  
Functional Evaluation ◽  
S Protein ◽  
Mutation Score ◽  
Functional Consequences ◽  
Genetic Clusters ◽  
Spatio Temporal

Background: The COVID-19 pandemic is associated with high morbidity and mortality, with the emergence of numerous variants. The dynamics of SARS-CoV-2 with respect to clade distribution is uneven, unpredictable and fast changing. Aims: Retrieving the complete genomes of SARS-CoV-2 from India and subjecting them to analysis on phylogenetic clade diversity, Spike (S) protein mutations and their functional consequences such as immune escape features and impact on infectivity. Methods: Whole genome of SARS-CoV-2 isolates (n=4,326) deposited from India during the period from January 2020 to December 2020 is retrieved from GISAID and various analyses performed using in silico tools. Results: Notable clade dynamicity is observed indicating the emergence of diverse SARS-CoV-2 variants across the country. GR clade is predominant over the other clades and the distribution pattern of clades is uneven. D614G is the commonest and predominant mutation found among the S-protein followed by L54F. Mutation score prediction analyses reveal that there are several mutations in S-protein including the RBD and NTD regions that can influence the virulence of virus. Besides, mutations having immune escape features as well as impacting the immunogenicity and virulence through changes in the glycosylation patterns are identified. Conclusions: The study has revealed emergence of variants with shifting of clade dynamics within a year in India. It is shown uneven distribution of clades across the nation requiring timely deposition of SARS-CoV-2 sequences. Functional evaluation of mutations in S-protein reveals their significance in virulence, immune escape features and disease severity besides impacting therapeutics and prophylaxis.

Analysis of spatio-temporal distribution of mortality due to gastric and colon cancer in Hungary and in Japan between 1986–2002

2008 ◽  
Vol 46 (05) ◽  
Author(s):  
K Tamássy ◽  
A Páldy ◽  
G Nádor ◽  
A Laborczi ◽  
L Pásztor ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Temporal Distribution ◽  
Spatio Temporal

Monitoring the spatio-temporal distribution of fish in Pohang-Namgu marine ranching area using acoustic survey

2019 ◽  
Vol 12 (1) ◽  
pp. 8-13
Author(s):  
Min-Seok KIM ◽  
Jun-Woo HWANG ◽  
Eun-Bi MIN ◽  
Eun-A YOON ◽  
Doo-Jin HWANG
Keyword(s):  
Temporal Distribution ◽  
Acoustic Survey ◽  
Spatio Temporal ◽  
Distribution Of Fish

Monitoring the spatio-temporal distribution of fish in Dangjin-Nanji island marine ranching area using echosounding

2018 ◽  
Vol 11 (1) ◽  
pp. 7-15
Author(s):  
Beom-Jun CHO ◽  
Eun-Bi MIN ◽  
Eun-A YOON ◽  
Doo-Jin HWANG
Keyword(s):  
Temporal Distribution ◽  
Spatio Temporal ◽  
Distribution Of Fish ◽  
Nanji Island

Influence of Planting Density on Root Spatio-Temporal Distribution of Different Types of Maize under High-Yielding Cultivation Conditions

2013 ◽  
Vol 38 (7) ◽  
pp. 1286-1294 ◽  
Author(s):  
Zong-Xin LI ◽  
Yuan-Quan CHEN ◽  
Qing-Cheng WANG ◽  
Kai-Chang LIU ◽  
Wang-Sheng GAO ◽  
...  
Keyword(s):  
Temporal Distribution ◽  
Planting Density ◽  
Cultivation Conditions ◽  
Different Types ◽  
Spatio Temporal

Recent advances in spatio-temporal distribution of endogenous phytohormones

2019 ◽  
Vol 37 (8) ◽  
pp. 806
Author(s):  
Yuxuan LI ◽  
Chunfeng DUAN ◽  
Yafeng GUAN
Keyword(s):  
Temporal Distribution ◽  
Recent Advances ◽  
Endogenous Phytohormones ◽  
Spatio Temporal

SPATIO-TEMPORAL DISTRIBUTION OF URANIUM CONCENTRATION IN SHALLOW AQUIFERS OF ARAVALLI TERRANE (NORTH GUJARAT), INDIA

2019 ◽  
Author(s):  
Rudra Mohan Pradhan ◽  
◽  
Karrie A. Weber ◽  
Karrie A. Weber ◽  
Daniel Snow ◽  
...  
Keyword(s):  
Uranium Concentration ◽  
Temporal Distribution ◽  
Shallow Aquifers ◽  
Spatio Temporal ◽  
North Gujarat

scholarly journals Variation Characteristics and Transportation of Aerosol, NO2, SO2, and HCHO in Coastal Cities of Eastern China: Dalian, Qingdao, and Shanghai

2021 ◽  
Vol 13 (5) ◽  
pp. 892
Author(s):  
Xiaomei Li ◽  
Pinhua Xie ◽  
Ang Li ◽  
Jin Xu ◽  
Zhaokun Hu ◽  
...  
Keyword(s):  
Eastern China ◽  
Temporal Distribution ◽  
Correlation Coefficients ◽  
Optical Absorption Spectroscopy ◽  
Near Surface ◽  
Mixing Ratios ◽  
Variation Characteristics ◽  
Spatio Temporal ◽  
Gas Volume ◽  
Transport Flux

This paper studied the method for converting the aerosol extinction to the mass concentration of particulate matter (PM) and obtained the spatio-temporal distribution and transportation of aerosol, nitrogen dioxide (NO2), sulfur dioxide (SO2), and formaldehyde (HCHO) based on multi-axis differential optical absorption spectroscopy (MAX-DOAS) observations in Dalian (38.85°N, 121.36°E), Qingdao (36.35°N, 120.69°E), and Shanghai (31.60°N, 121.80°E) from 2019 to 2020. The PM2.5 measured by the in situ instrument and the PM2.5 simulated by the conversion formula showed a good correlation. The correlation coefficients R were 0.93 (Dalian), 0.90 (Qingdao), and 0.88 (Shanghai). A regular seasonality of the three trace gases is found, but not for aerosols. Considerable amplitudes in the weekly cycles were determined for NO2 and aerosols, but not for SO2 and HCHO. The aerosol profiles were nearly Gaussian, and the shapes of the trace gas profiles were nearly exponential, except for SO2 in Shanghai and HCHO in Qingdao. PM2.5 presented the largest transport flux, followed by NO2 and SO2. The main transport flux was the output flux from inland to sea in spring and winter. The MAX-DOAS and the Copernicus Atmosphere Monitoring Service (CAMS) models’ results were compared. The overestimation of NO2 and SO2 by CAMS is due to its overestimation of near-surface gas volume mixing ratios.

scholarly journals Integrated structured light architectures

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Randy Lemons ◽  
Wei Liu ◽  
Josef C. Frisch ◽  
Alan Fry ◽  
Joseph Robinson ◽  
...  
Keyword(s):  
Degrees Of Freedom ◽  
Temporal Distribution ◽  
Multiple Degrees Of Freedom ◽  
Beam Combination ◽  
Angular Momenta ◽  
Field Control ◽  
Topological States ◽  
Spatio Temporal ◽  
Temporal Field ◽  
Structural Versatility

AbstractThe structural versatility of light underpins an outstanding collection of optical phenomena where both geometrical and topological states of light can dictate how matter will respond or display. Light possesses multiple degrees of freedom such as amplitude, and linear, spin angular, and orbital angular momenta, but the ability to adaptively engineer the spatio-temporal distribution of all these characteristics is primarily curtailed by technologies used to impose any desired structure to light. We demonstrate a laser architecture based on coherent beam combination offering integrated spatio-temporal field control and programmability, thereby presenting unique opportunities for generating light by design to exploit its topology.

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