Foldscope: Diagnostic accuracy and feasibility of its use in national malaria control program

2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Sagar Khadanga ◽  
Sweta Gupta ◽  
BijinaJohn Mathews ◽  
SaiNikhila Ghantaa ◽  
KrishnaChaitanya Amerneni ◽  
...  
PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e69865 ◽  
Author(s):  
Valéry Ridde ◽  
Thomas Druetz ◽  
Serge Poppy ◽  
Seni Kouanda ◽  
Slim Haddad

2021 ◽  
Author(s):  
Kelry Mazurega Oliveira Dinelly ◽  
Sheila Vitor-Silva ◽  
Jose Diego Brito-Sousa ◽  
Vanderson Souza Sampaio ◽  
Milena Gabriela Oliveira Silva ◽  
...  

Abstract BackgroundRelapses in vivax malaria have posed great challenges to malaria control, accounting for a great proportion of reported cases. Knowing the real effectiveness of 7 day primaquine (PQ) scheme is crucial to understand not only the cost-effectiveness of implementing new anti-hypnozoite drugs but how health education strategies can guarantee better compliance and be reinforced. This study aimed the evaluation of the daily supervised treatment effect with chloroquine and PQ (in consented patients) versus prescription without supervision (non-consented patients), and the outcome was the passive detection of new positive thick blood smears until 180 days, based on the official data records from the National Malaria Control Program. The recurrences seen in the real life were therefore used as a surrogate for true relapses. Patients under supervised treatment had a lower risk of recurrence until day 180 when compared to the unsupervised treatment (17.9% vs 36.1%; p=0.027). The lack of consent in the non-supervised group (which followed standard of care in the real life) enabled proper comparison, as consent itself could lead to better compliance in this group. Future studies should scale such analysis to different settings in the Brazilian Amazon.


1995 ◽  
Vol 10 (3) ◽  
pp. 154-160 ◽  
Author(s):  
Rocio Sáenz ◽  
Richard A. Bissell ◽  
Francisco Paniagua

AbstractIntroduction:In recent years, controversy has surrounded the issue of whether infectious disease should be considered a serious potential consequence of natural disasters. This article contributes to this debate with evidence of a significant outbreak of malaria in Costa Rica's Atlantic region after the 1991 earthquake and subsequent floods.Methods:This study is an epidemiologic investigation of the incidence of malaria for the periods of 22 months before the April 1991 Limon earthquake and for 13 months afterward. Data were obtained from the Costa Rican Ministry of Health's malaria control program.Results:Some of the cantons in the region experienced increases in the incidence of malaria as high as 1,600% and 4,700% above the average monthly rate for the pre-earthquake period (p ≤0.01). Causal mechanisms are postulated as relating to changes in human behavior (increased exposure to mosquitoes while sleeping outside, and a temporary pause in malaria control activities), changes in the habitat that were beneficial to mosquito breeding (landslide deforestation, river damming, and rerouting), and the floods of August 1991.Conclusions:It is recommended that there be enhanced awareness of the potential consequences of disaster-wrought environmental changes.Date of Event: 22 April 1991; Type: Earthquake, 7.4 Richter scale; Location: Costa Rica; Number of deaths and casualties: 54 deaths and 505 moderate to severe injuries.


2020 ◽  
Author(s):  
Tete Sitou Amouh ◽  
Saidou Malam Ekoye ◽  
Césaire Damien Ahanhanzo ◽  
Tinga Robert Guiguemdé ◽  
Issiaka Sombié

Abstract In Sahel countries in West Africa malaria remains a public health scourge. To strengthen the fight against malaria, weaknesses, and solutions must be identified before programs implementation. This study reports experiences gained from collaborations between decision-makers and researchers. This project was undertaken in the framework of the regional World Bank funded project titled: Malaria and Neglected Tropical Diseases in the Sahel (SM/NTD). The objectives of this World Bank program are to identifying bottlenecks in program implementation as well as the related research questions they enticed. National malaria control program managers and prioritization workshops were used as working method to identify research questions. These identified priority research questions were implemented in selected countries. The results of this study showed that priority issues were related to prevention, governance, drugs, monitoring, and evaluation of programs. The first five priority questions were related to (1) factors of compliance with drug doses for the second and third days during the seasonal chemoprevention (SMC) campaigns, (2) the contribution of community-based distributors to the management of severe cases of malaria in under 5 years-old children, (3) the SMC efficacy, (4) artemisinin-based combination therapy (ACTs) tolerance and efficacy according to existing guidelines, and (5) the quality of malaria control at all levels of the health system. In conclusion, this work showed the effectiveness of collaboration between implementers, programs managers, and researchers in identifying research questions. Furthermore, the results of this study will contribute to improve the implementation of malaria control programs across African countries.


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