scholarly journals Novel method of plugging the hole: Anatomical and functional outcomes of human amniotic membrane-assisted macular hole surgery

2020 ◽  
Vol 32 (4) ◽  
pp. 361
Author(s):  
Ramesh Venkatesh ◽  
NareshKumar Yadav ◽  
Sherina Thomas ◽  
Arpitha Pereira ◽  
KBhujang Shetty
Keyword(s):  
Macular Hole ◽  
Amniotic Membrane ◽  
Functional Outcomes ◽  
Human Amniotic Membrane ◽  
Macular Hole Surgery ◽  
Novel Method

Human amniotic membrane plug technique for macular hole surgery: A case report

2020 ◽  
Vol 43 (4) ◽  
pp. e151-e152 ◽  
Author(s):  
C. Florent ◽  
L. Coupier ◽  
P.-Y. Mérité ◽  
F. Meyer ◽  
S. Guigou
Keyword(s):  
Case Report ◽  
Macular Hole ◽  
Amniotic Membrane ◽  
Human Amniotic Membrane ◽  
Macular Hole Surgery

scholarly journals Comparison between Cryopreserved and Dehydrated Human Amniotic Membrane Graft in Treating Challenging Cases with Macular Hole and Macular Hole Retinal Detachment

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Yu-Hsuan Huang ◽  
Der-Chong Tsai ◽  
Lei-Chi Wang ◽  
Shih-Jen Chen
Keyword(s):  
Retinal Detachment ◽  
Macular Hole ◽  
Amniotic Membrane ◽  
Functional Outcomes ◽  
Case Series ◽  
Human Amniotic Membrane ◽  
Closure Rate ◽  
Macular Hole Retinal Detachment ◽  
Prior Surgery ◽  
Feasible Alternative

Purpose. To evaluate the surgical outcomes of cryopreserved and dehydrated human amniotic membrane (hAM) graft transplantation for macular hole (MH) and macular hole retinal detachment (MHRD) repair. Materials and Methods. This retrospective, interventional case series was conducted in two hospitals. Two types of hAM grafts, namely, the dehydrated form (AmnioGen, HCT Regenerative, Taiwan) and the cryopreserved form (AmnioGraft, Bio-Tissue, Miami, FL), were consecutively used in MH surgeries. Anatomical and functional outcomes between the 2 types of hAM grafts were compared. Results. Seventeen patients (mean age: 62.1 ± 10.0 years, 9 (52.9%) males) were enrolled. Of them, 11 patients had persistent MH, 3 had MH without prior surgery, and 3 had MHRD. A cryopreserved hAM graft was used in 10 patients, and a dehydrated hAM graft was used in 8 patients. One patient used a cryopreserved hAM in the first MH surgery and a dehydrated hAM in the second surgery for extramacular hole with retinal detachment. After a 6-month follow-up, 13 (76.5%) patients had sealed MHs. The average visual acuity (VA) of cases with sealed MHs improved from 1.38 ± 0.62 to 1.12 ± 0.47 logMAR (p=0.03). In the other 4 cases with persistent MH, 3 had graft dislocation and 1 had a reopened MH with graft contraction. There were no significant differences in closure rate (80.00% vs. 71.43%, p=0.68) or VA improvement (0.19 ± 0.37 logMAR vs. 0.15 ± 0.41 logMAR, p=0.85) between the 2 kinds of hAM graft. Conclusion. This preliminary case series showed that both cryopreserved hAM and dehydrated hAM are feasible alternative grafts for either persistent or recurrent MH. Both approaches have similar anatomical and functional outcomes.

Human amniotic membrane for failed macular hole. A case of initial unsuccessful outcome that resolved after amniotic membrane exchange

2021 ◽  
pp. 112067212110589
Author(s):  
Tomaso Caporossi ◽  
Lorenzo Governatori ◽  
Tommaso Verdina ◽  
Stanislao Rizzo
Keyword(s):  
Visual Acuity ◽  
Macular Hole ◽  
Amniotic Membrane ◽  
Sulfur Hexafluoride ◽  
Silicone Oil ◽  
Human Amniotic Membrane ◽  
Second Surgery ◽  
Myopic Macular Hole ◽  
Oil Injection ◽  
Membrane Patch

Introduction We described a case of initial unsuccessful outcome of failed macular hole treated with amniotic membrane, that resolved after amniotic membrane exchange and silicone oil injection. Case Description a woman affected by a high myopic macular hole that had failed to close after multiple surgeries, had been treated using an amniotic membrane graft and 20% sulfur hexafluoride but, after the gas reabsorption, the macular hole was still open, and the amniotic membrane. A second surgery with a second amniotic membrane patch and silicone oil was carried out. Two weeks after the procedure the macular hole closed, and the final visual acuity improved from 20/400 to 20/100. Conclusions In this case, a second surgery, using a new amniotic membrane graft and a longer-lasting endotamponade, closed the hole and improved the visual acuity.

EARLY POSTOPERATIVE MACULAR MORPHOLOGY AND FUNCTIONAL OUTCOMES AFTER SUCCESSFUL MACULAR HOLE SURGERY

Retina ◽  
2007 ◽  
Vol 27 (2) ◽  
pp. 165-168 ◽  
Author(s):  
GEN MIURA ◽  
SATOSHI MIZUNOYA ◽  
MIYUKI ARAI ◽  
MASANORI HAYASHI ◽  
SHUICHI YAMAMOTO
Keyword(s):  
Macular Hole ◽  
Functional Outcomes ◽  
Macular Hole Surgery

Parafoveal atrophy after human amniotic membrane graft for macular hole in patients with high myopia

2020 ◽  
pp. bjophthalmol-2019-315603
Author(s):  
Der-Chong Tsai ◽  
Yu-Hsuan Huang ◽  
Shih-Jen Chen
Keyword(s):  
Macular Hole ◽  
Amniotic Membrane ◽  
Axial Length ◽  
High Myopia ◽  
Rare Complication ◽  
Case Series ◽  
Visual Outcome ◽  
Human Amniotic Membrane ◽  
Significant Difference

PurposeTo report the surgical outcome and postoperative hypopigmented change around fovea among patients with high myopia who received human amniotic membrane (hAM) graft transplantation for macular hole (MH).MethodThis retrospective, interventional case series included 10 eyes of 10 consecutive patients (5 (50%) male) with high myopia (axial length over 26.5 mm) who received hAM graft to treat persisted or chronic MH with or without retinal detachment in two hospitals. Postoperative parafoveal atrophy was identified with colour fundus picture and structure optical coherent tomography. Baseline characteristics and short-term visual outcome were analysed.ResultsThe preoperative mean (±SD) axial length and MH diameter were 29.9 (±1.8) mm and 881.8 (±438.5) μm, respectively. After hAM transplantation, seven (70%) eyes had complete MH closure and the mean best-corrected visual acuity (BCVA) improved from 1.26 (±0.48) logarithm of minimal angle of resolution (logMAR) before operation to 1.11 (±0.44) logMAR on the last visit (p=0.074). Patchy atrophy-like depigmentation developed around the MH lesion in four (40.0%) eyes as early as in the first month after surgery. None of them had visual worsening. In terms of demographics, axial length, MH size, ocular history, preoperative BCVA and postoperative BCVA, there was no significant difference between those with and without the parafoveal atrophy. No graft rejection and inflammation happened during the follow-up.ConclusionParafovea atrophy, a rare complication in the conventional MH surgery, was observed in 40% of eyes with highly myopic MH after hAM graft transplantation. The pathogenesis and long-term consequence need further investigations.

A Human Amniotic Membrane Plug to Promote Retinal Breaks Repair and Recurrent Macular Hole Closure

Retina ◽  
2019 ◽  
Vol 39 ◽  
pp. S95-S103 ◽  
Author(s):  
Stanislao Rizzo ◽  
Tomaso Caporossi ◽  
Ruggero Tartaro ◽  
Lucia Finocchio ◽  
Fabrizio Franco ◽  
...  
Keyword(s):  
Macular Hole ◽  
Amniotic Membrane ◽  
Human Amniotic Membrane ◽  
Retinal Breaks ◽  
Hole Closure
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