HIV-1 plasma RNA viral load and CD4 cell count in drug-naïve HIV-1 infected patients in Kaduna State, Nigeria

2021 ◽  
Vol 23 (1) ◽  
pp. 46
Author(s):  
MohammedIbrahim Tahir ◽  
MaryamAminu Aminu ◽  
AhmedBabangida Suleiman ◽  
AhmedSaraja Opaluwa ◽  
AbdurrahmanEl-Fulaty Ahmad ◽  
...  
Keyword(s):  
Viral Load ◽  
Cell Count ◽  
Cd4 Cell Count ◽  
Drug Naïve ◽  
Cd4 Cell ◽  
Plasma Rna ◽  
Hiv 1

scholarly journals Frequency of Cytomegalovirus Viral Load in Iranian Human Immunodeficiency Virus-1-Infected Patients with CD4+ Counts <100 Cells/mm3

Intervirology ◽  
2021 ◽  
pp. 1-5
Author(s):  
Mohammad Reza Jabbari ◽  
Hoorieh Soleimanjahi ◽  
Somayeh Shatizadeh Malekshahi ◽  
Mohammad Gholami ◽  
Leila Sadeghi ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Viral Load ◽  
Cell Count ◽  
Previous History ◽  
Cd4 Count ◽  
Cd4 Cell Count ◽  
Cell Counts ◽  
Immunodeficiency Virus ◽  
Cd4 Cell ◽  
Hiv 1

<b><i>Objectives:</i></b> The aim of present work was to assess cytomegalovirus (CMV) viremia in Iranian human immunodeficiency virus (HIV)-1-infected patients with a CD4+ count &#x3c;100 cells/mm<sup>3</sup> and to explore whether CMV DNA loads correlate with CD4+ cell counts or associated retinitis. <b><i>Methods:</i></b> This study was conducted at the AIDS research center in Iran on HIV-1-infected patients with CD4+ count &#x3c;100 cells/mm<sup>3</sup>, antiretroviral therapy-naive, aged ≥18 years with no previous history of CMV end-organ disease (CMV-EOD). <b><i>Results:</i></b> Thirty-nine of 82 patients (47.56%) had detectable CMV viral load ranging from 66 to 485,500 IU/mL. CMV viral load in patients with retinitis ranges from 352 to 2,720 IU/mL, and it was undetectable in 2 patients. No significant associations between CMV viremia and CD4+ cell count was found (<i>p</i> value = 0.31), whereas significant association of CMV viremia in HIV-infected patients with retinitis was found (<i>p</i> &#x3c; 0.02). <b><i>Conclusions:</i></b> We estimated the frequency of CMV viral load infection in Iranian HIV-1-infected patients with a CD4+ cell count &#x3c;100 mm<sup>3</sup>/mL in the largest national referral center for HIV-1 infection in Iran. Further research is required on the relevance of CMV viral load in diagnostic and prognostic value of CMV-EOD.

scholarly journals Impact on life expectancy of HIV-1 positive individuals of CD4+ cell count and viral load response to antiretroviral therapy

AIDS ◽  
2014 ◽  
Vol 28 (8) ◽  
pp. 1193-1202 ◽  
Author(s):  
Margaret T. May ◽  
Mark Gompels ◽  
Valerie Delpech ◽  
Kholoud Porter ◽  
Chloe Orkin ◽  
...  
Keyword(s):  
Viral Load ◽  
Antiretroviral Therapy ◽  
Life Expectancy ◽  
Cell Count ◽  
Cd4 Cell Count ◽  
Load Response ◽  
Cd4 Cell ◽  
Hiv 1 ◽  
Viral Load Response

The effect of baseline CD4 cell count and HIV-1 viral load on the efficacy and safety of nevirapine or efavirenz-based first-line HAART

AIDS ◽  
2005 ◽  
Vol 19 (5) ◽  
pp. 463-471 ◽  
Author(s):  
F van Leth ◽  
S Andrews ◽  
B Grinsztejn ◽  
E Wilkins ◽  
MK Lazanas ◽  
...  
Keyword(s):  
Viral Load ◽  
Cell Count ◽  
Efficacy And Safety ◽  
First Line ◽  
Cd4 Cell Count ◽  
Cd4 Cell ◽  
Hiv 1

scholarly journals Comparison of CD4 Cell Count, Viral Load, and Other Markers for the Prediction of Mortality among HIV‐1–Infected Kenyan Pregnant Women

2009 ◽  
Vol 199 (9) ◽  
pp. 1292-1300 ◽  
Author(s):  
Elizabeth R. Brown ◽  
Phelgona Otieno ◽  
Dorothy A. Mbori‐Ngacha ◽  
Carey Farquhar ◽  
Elizabeth M. Obimbo ◽  
...  
Keyword(s):  
Viral Load ◽  
Pregnant Women ◽  
Cell Count ◽  
Cd4 Cell Count ◽  
Prediction Of Mortality ◽  
Cd4 Cell ◽  
Hiv 1

Maternal viral load, CD4 cell count and vertical transmission of HIV-1

1998 ◽  
Vol 54 (2) ◽  
pp. 113-117 ◽  
Author(s):  
Siobhan O'Shea ◽  
Marie-Louise Newell ◽  
David T. Dunn ◽  
Marie-Cruz Garcia-Rodriguez ◽  
Isabel Bates ◽  
...  
Keyword(s):  
Viral Load ◽  
Cell Count ◽  
Vertical Transmission ◽  
Cd4 Cell Count ◽  
Maternal Viral Load ◽  
Vertical Transmission Of Hiv ◽  
Cd4 Cell ◽  
Hiv 1

Association of syncytium-inducing phenotype of HIV-1 with CD4 cell count, viral load and sociodemographic characteristics

AIDS ◽  
1998 ◽  
Vol 12 (11) ◽  
pp. 1341-1346 ◽  
Author(s):  
Hansjakob Furrer ◽  
Thomas Wendland ◽  
Christoph Minder ◽  
Anna Christen ◽  
Jan von Overbeck ◽  
...  
Keyword(s):  
Viral Load ◽  
Cell Count ◽  
Sociodemographic Characteristics ◽  
Cd4 Cell Count ◽  
Cd4 Cell ◽  
Hiv 1

scholarly journals Effectiveness of tipranavir versus darunavir as a salvage therapy in HIV-1 treatment-experienced patients

2016 ◽  
Vol 10 (09) ◽  
pp. 982-987 ◽  
Author(s):  
Juan Carlos Domínguez-Hermosillo ◽  
José Antonio Mata-Marin ◽  
Norma Estela Herrera-González ◽  
Marcelino Chávez-García ◽  
Gloria Huerta-García ◽  
...  
Keyword(s):  
Viral Load ◽  
Cell Count ◽  
Salvage Therapy ◽  
Medical Center ◽  
Resistance Mutation ◽  
Cd4 Cell Count ◽  
National Medical ◽  
Significant Difference ◽  
Cd4 Cell ◽  
Hiv 1

Introduction: Although both tipranavir (TPV) and darunavir (DRV) represent important options for the management of patients with multi-protease inhibitor (PI)-resistant human immunodeficiency virus (HIV), currently there are no studies comparing the effectiveness and safety of these two drugs in the Mexican population. The aim of this study was to compare the effectiveness of TPV versus DRV as a salvage therapy in HIV-1 treatment-experienced patients. Methodology: This was a comparative, prospective, cohort study. Patients with HIV and triple-class drug resistance evaluated at the Hospital de Infectología “La Raza”, National Medical Center, were included. All patients had the protease and retrotranscriptase genotype; resistance mutation interpretation was done using the Stanford database. Results: A total of 35 HIV-1 triple-class drug-resistant patients were analyzed. All of them received tenofovir and raltegravir, 22 received darunavir/ritonavir (DRV/r), and 13 received tipranavir/ritonavir (TPV/r) therapies. The median baseline RNA HIV-1 viral load and CD4+ cell count were 4.34 log (interquartile range [IQR], 4.15–4.72) and 267 cells/mm3 (IQR, 177–320) for the DRV/r group, and 4.14 log (IQR, 3.51–4.85) and 445 cells/mm3 (IQR, 252–558) for the TPV/r group. At week 24 of treatment, 91% of patients receiving DRV/r and 100% of patients receiving TPV/r had an RNA HIV-1 viral load < 50 copies/mL and a CD4+ cell count of 339 cells/mm3 (IQR, 252–447) and 556 cells/mm3 (IQR, 364–659), respectively. Conclusions: No significant difference was observed between DRV/r and TPV/r in terms of virological suppression in HIV-1 patients who were highly experienced in antiretroviral therapy.

Association of HLA profiles with early plasma viral load, CD4+ cell count and rate of progression to AIDS following acute HIV-1 infection

AIDS ◽  
1998 ◽  
Vol 12 (16) ◽  
pp. 2107-2113 ◽  
Author(s):  
Alfred J. Saah ◽  
Donald R. Hoover ◽  
Shigui Weng ◽  
Mary Carrington ◽  
John Mellors ◽  
...  
Keyword(s):  
Viral Load ◽  
Cell Count ◽  
Plasma Viral Load ◽  
Cd4 Cell Count ◽  
Rate Of Progression ◽  
Acute Hiv ◽  
Cd4 Cell ◽  
Hiv 1
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