Anterior bladder wall thickness, post-void urine residue, and bladder emptying efficiency as indicators of bladder dysfunction in Nigerian men with benign prostatic hyperplasia

2020 ◽  
Vol 23 (9) ◽  
pp. 1215
Author(s):  
BU Eze ◽  
TU Mbaeri ◽  
JC Orakwe
2013 ◽  
Vol 7 (5-6) ◽  
pp. 317 ◽  
Author(s):  
Kamyar Eghbali ◽  
Mohammad Reza Shayegan ◽  
Sina Kianoush

Introduction: According to previous studies, aging, gender, bladder volume and pathological states, such as bladder outflow obstruction, affect bladder wall thickness (BWT). The aim of this study was to evaluate the correlation between BWT and the International Prostatic Symptom Score (IPSS) in patients with benign prostatic hyperplasia (BPH) before and after tamsulosin treatment.Methods: In this study, 60 BPH patients were included. After obtaining informed consent, data were gathered using questionnaires to determine IPSS. After that, prostate-specific antigen was measured and a clinical examination, including a digital rectal examination, was performed for all patients. BWT was determined by transabdominal ultrasound. Finally, all patients were treated with tamsulosin (0.4 mg/day) for 2 months. After completing treatment, the IPSS and BWT were measured again and compared with the initial findings.Results: In total, 44 patients completed treatment. Patients aged 61.7 ± 9.2 years old. The mean ± standard deviation of IPSS and BWT were 14.6 ± 5.0 and 5.36 ± 1.28 mm before treatment, while they significantly (p < 0.0001) decreased to 8.2 ± 4.7 and 4.69 ± 1.23 mm, respectively, after treatment. Chi-square test showed that the decrease in BWT was significantly correlated with the improvement in IPSS (p = 0.002; r = 0.449).Conclusion: After treatment with tamsulosin, patients experienced a reduction in their BWT which was significantly correlated with improvement in their IPSS. We conclude that transabdominal evaluation of BWT could be included in the follow-up assessment in BPH.


2020 ◽  
Vol 27 (12) ◽  
pp. 2553-2557
Author(s):  
Moin Anwar ◽  
Muhammad Saifullah ◽  
Muhammad Tahir Bashir Malik ◽  
Muhammad Irfan Munir ◽  
Muhammad Akmal ◽  
...  

Objectives: Our objective was determination of the correlation between mean bladder wall thickness and mean IPSS in BPH diagnosed patients. Study Design: Cross sectional study. Setting: Department of Urology & Renal Transplantation, Punjab Medical College / Allied Hospital, Faisalabad. Period: Six months from 01-04-2016 to 30-09-2016. Material & Methods: Total 70 patients were enrolled for study from outpatient department of Urology, AHF. IPSS was calculated and recorded. Transabdominal ultrasound KUB was done to measure bladder wall thickness. Urine complete examination and culture was done to rule out UTI. Existence of bladder tumor was ruled out by previous history and ultrasonography. The data was collected on a Proforma by myself. Results: Out of 70 enrolled cases, 47.14% (n=33) were aged 50-60 years whereas 52.86% (n=37) were 61-70 years of age. Mean age was calculated as 61.27+5.31 years. Mean Bladder Wall thickness was 3.64+0.72 and IPSS was calculated to be 12.84+2.79 (r0.9056). Correlation between mean bladder wall thickness and mean IPSS in patients having benign prostatic hyperplasia was calculated as significant. Conclusion: In patients suffering from BOO due to BPH, we have found a very strong positive correlation between mean IPSS and mean BWT. However, bigger studies using standardized techniques are required to establish this fact.


2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Xuke Han ◽  
Yang Gao ◽  
Xuan Yin ◽  
Shengju Wang ◽  
Xiaoran Zhang ◽  
...  

Previous studies observed have reported that electroacupuncture (EA) is effective in relieving diabetic bladder dysfunction (DBD); however, little is known about the mechanism. Therefore, we explored the effects and mechanisms of EA on DBD in streptozotocin–high-fat diet- (STZ–HFD-) induced diabetic rats. The Sprague-Dawley male rats were divided randomly into four groups: normal group, diabetes mellitus group (DM group), DM with EA treatment group (EA group), and DM with sham EA treatment group (sham EA group). After 8 weeks of EA treatment, the body weight, serum glucose, bladder weight, and cystometrogram were evaluated. The bladder wall thickness was examined by abdominal ultrasound imaging. After the transabdominal ultrasound measurements, hematoxylin-eosin (HE) staining was used to observe the bladder mucosa layer. The bladder detrusor smooth muscle cells (SMCs) and fibroblasts were observed under transmission electron microscopy (TEM). The phospho-myosin light chain (p-MLC), phospho-myosin light chain kinase (p-MLCK), and phospho-myosin phosphatase target subunit 1 (p-MYPT1) levels in the bladder were examined using Western blot. The bladder weight, serum glucose, bladder wall thickness, volume threshold for micturition, and postvoid residual (PVR) volume in the diabetic rats were significantly higher than those in the control animals. EA treatment significantly reduced the bladder weight, bladder wall thickness, volume threshold for micturition, and PVR volume in diabetic rats. EA caused a significant increase in the MLC dephosphorylation and MLCK phosphorylation levels in the group compared to the sham EA and model groups. EA reduced the infiltration of inflammatory cells in the bladder mucosa layer of diabetic rats. In addition, EA repaired the damaged bladder detrusor muscle of diabetic rats by reducing mitochondrial damage of the SMCs and fibroblasts. Therefore, EA could reduce the bladder hypertrophy to ameliorate DBD by reversing the impairment in the mucosa layer and detrusor SMCs, which might be mainly mediated by the regulation of p-MLC and p-MLCK levels.


1998 ◽  
Vol 159 (3) ◽  
pp. 761-765 ◽  
Author(s):  
CARLO MANIERI ◽  
SIMON ST. C. CARTER ◽  
GIANFRANCO ROMANO ◽  
ALBERTO TRUCCHI ◽  
MARCO VALENTI ◽  
...  

Author(s):  
J. Sparago ◽  
N. Rademacher ◽  
S. Dehghanpir ◽  
J. Post ◽  
C. C. Liu ◽  
...  

2021 ◽  
pp. 5-9
Author(s):  
Prasenjit Bhowmik ◽  
Soumendranath Mandal ◽  
Gaurav Sharma ◽  
Bandhan Bahal ◽  
Prashant Gupta ◽  
...  

Objectives: To dene the diagnostic accuracy of intravesical protrusion of prostate (IPP), bladder wall thickness (BWT) and prostate volume (PV) in diagnosis of bladder outlet obstruction (BOO) and prediction of future acute urinary retention (AUR). A prospective Materials and methods: study of 127 patients, presenting with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (BPH) were enrolled with 50 patients among them manifesting AUR. 35 normal persons were selected as control group. After inclusion, all patients underwent transabdominal ultrasound and pressure ow urodynamic study (UDS). UDS parameter, BOO index (BOOI) were used as a reference standard for stratifying the patients into two groups, BOO and non-BOO. The sono-morphological parameters, IPP, BWT and PV were used to compare between these two groups with calculating the diagnostic accuracy for each individual index. IPP, BWT Results: and PV had statistically signicant difference between group 1 (BOOI < 40) and 2 ( BOOI > 40) with strong correlation with BOOI. The Pearson's correlation coefcient (r) for IPP, BWT and PV were 0.762, 0.702 and 0.660 respectively. The AUC for IPP, BWT and PV were 0.824, 0.786 and 0.650 with highest accuracy for IPP (79.2%) at cutoff value of 7 mm. Using the same threshold value, IPP had higher statistical difference than BWT in predicting AUR with similar diagnostic accuracy of IPP and BWT together. IPP and BWT in conjunction with PV in place Conclusions: of UDS had good clinical utility in diagnosis of BOO due to BPH and future AUR prediction.


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