New Opportunities and New Challenges

2018 ◽  
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Keyword(s):  
New Challenges

New challenges to image processing posed by cryo-Electron microscopy of single particles

1991 ◽  
Vol 49 ◽  
pp. 422-423
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Joachim Frank
Keyword(s):  
Electron Microscopy ◽  
Phase Contrast ◽  
Particle Orientation ◽  
Single Particles ◽  
Contrast Transfer Function ◽  
Virtual Absence ◽  
Cryo Electron Microscopy ◽  
Spatial Frequencies ◽  
New Challenges ◽  
Particle Images

Compared with images of negatively stained single particle specimens, those obtained by cryo-electron microscopy have the following new features: (a) higher “signal” variability due to a higher variability of particle orientation; (b) reduced signal/noise ratio (S/N); (c) virtual absence of low-spatial-frequency information related to elastic scattering, due to the properties of the phase contrast transfer function (PCTF); and (d) reduced resolution due to the efforts of the microscopist to boost the PCTF at low spatial frequencies, in his attempt to obtain recognizable particle images.

The new challenges for the regulatory authorities

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Vol 38 (11) ◽  
pp. S127-S128
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M Marty
Keyword(s):  
Regulatory Authorities ◽  
New Challenges

Patient Safety Law Presents New Challenges

2005 ◽  
Vol 38 (17) ◽  
pp. 80
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NELLIE BRISTOL
Keyword(s):  
Patient Safety ◽  
New Challenges

New Challenges Created by Success in Peace Psychology

2012 ◽  
Author(s):  
Maggie Campbell ◽  
Katherine Lacasse ◽  
Lucas Mazur ◽  
Rashmi Nair
Keyword(s):  
New Challenges ◽  
Peace Psychology

Floods and hydroinformatics: new challenges

2007 ◽  
pp. 33-36
Author(s):  
David Fortune
Keyword(s):  
New Challenges
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